Journal
FOOD BIOSCIENCE
Volume 47, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.fbio.2022.101659
Keywords
Mussel polysaccharide; Structural characterization; Antioxidant activity
Categories
Funding
- National Key Research and Development Program of China [2020YFD0900902]
- General scientific research project of Zhejiang Provincial Department of Education [Y202043175]
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A new water-soluble polysaccharide was extracted and purified from mussels, and its structure and cellular antioxidant levels were studied. The polysaccharide was mainly composed of glucose and showed characteristic polysaccharide bands. Moreover, it was found that the polysaccharide could protect cells from oxidative stress by increasing antioxidant enzyme activities and reducing oxidative damage markers.
In this study, a new type of water-soluble polysaccharide was extracted and purified from mussels, and its structure and cellular antioxidant levels were studied. Mussel polysaccharide (MP 4.25 x 10(3) Da) is composed mainly of glucose, with a small amount of galactosamine hydrochloride, glucosamine hydrochloride, and galactose. MP shows characteristic polysaccharide bands in Fourier transform NMR and infrared spectroscopy. The main chain connection mode of MP is the glycosidic bond of -> 4)-alpha-D-Glcp-(1 -> , and the end group alpha-D-Glcp(1 -> and alpha-D-Glcp-(1 -> 6)-alpha-D-Glcp-(1 -> pass -> 4,6)-alpha-D-Glcp-(1 -> . The O-6 bond is connected to the main chain. Moreover, MP could protect RAW264.7 cells against H2O2-induced oxidative stress by increasing catalase (CAT), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) activities and reducing the content of malondialdehyde (MDA). This is expected to make MP an important member of the antioxidant family.
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