Journal
FRONTIERS IN PSYCHIATRY
Volume 13, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fpsyt.2022.763380
Keywords
cultural psychiatry; computational psychiatry; computational phenotyping; major depressive disorder (MDD); evolutionary psychiatry
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Funding
- Australian Laureate Fellowship Project [FL170100160]
- Social Sciences and Humanities Research Council Doctoral Fellowship [752-2019-0065]
- Wellcome Trust [088130/Z/09/Z]
- Canada First Research Excellence Fund (CFREF), Healthy Brains for Healthy Lives
- Canadian Framework for Brain Health
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The paper proposes an integrative perspective on evolutionary, cultural and computational approaches to psychiatry, highlighting the importance of systemic thinking. By integrating these three approaches, it can better guide research and practice in psychiatry.
This paper proposes an integrative perspective on evolutionary, cultural and computational approaches to psychiatry. These three approaches attempt to frame mental disorders as multiscale entities and offer modes of explanations and modeling strategies that can inform clinical practice. Although each of these perspectives involves systemic thinking, each is limited in its ability to address the complex developmental trajectories and larger social systemic interactions that lead to mental disorders. Inspired by computational modeling in theoretical biology, this paper aims to integrate the modes of explanation offered by evolutionary, cultural and computational psychiatry in a multilevel systemic perspective. We apply the resulting Evolutionary, Cultural and Computational (ECC) model to Major Depressive Disorder (MDD) to illustrate how this integrative approach can guide research and practice in psychiatry.
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