Journal
FRONTIERS IN GENETICS
Volume 13, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fgene.2022.893358
Keywords
gene Expression; pan-cancer; GSE data; prognostic analysis; TCGA; immune infiltration
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Funding
- National Natural Science Foundation of China [62002189, 62002187, 62102200]
- Natural Science Foundation of Shandong Province, China [ZR2020QF038, ZR2021MH104, ZR2020MH208]
- Young Taishan Scholars Program, Shandong, China [tsqn201909178]
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This paper focuses on studying the differential mechanism of gene expression of UBE2C in various tumors and its correlation with prognosis, clinical features, immunity, methylation, and other characteristics, based on public databases.
Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression, and may be involved in cancer progression. In this paper, on the basis of public databases, we study the expression differential mechanism of gene expression of UBE2C in various tumors and the performance of prognosis, clinical features, immunity, methylation, etc.
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