Journal
FRONTIERS IN CHEMISTRY
Volume 10, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fchem.2022.867318
Keywords
matrine; extraction; synthesis; derivatization; molecular mechanism; pharmacological effects
Categories
Funding
- National Natural Science Foundation of China [U1932130]
- Key Program of Shaanxi Provincial Science and Technology Department [2021SF-303]
- Key Program of Shaanxi Provincial Education Department [20JS138]
- Program of Shaanxi Administration of Traditional Chinese Medicine [2019-ZZ-ZY009]
- Key Program of Weiyang District Bureau of Science, Technology and Industry Information Technology [201928]
Ask authors/readers for more resources
Matrine, an alkaloid extracted from traditional Chinese herbs, combines the advantages of traditional herbs and chemotherapy drugs, showing distinct benefits in preventing and improving chronic diseases. Recent research has focused on its anti-atherosclerosis, anti-tumor, and anti-inflammatory properties, providing new insights for drug development in related fields.
Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora flavescentis, Sophora alopecuroides, Sophora root, etc. It has the dual advantages of traditional Chinese herbs and chemotherapy drugs. It exhibits distinct benefits in preventing and improving chronic diseases such as cardiovascular disease and tumors. The review introduced recent research progresses on extraction, synthesis and derivatization of Matrine. The summary focused on the latest research advances of Matrine on anti-atherosclerosis, anti-hypertension, anti-ischemia reperfusion injury, anti-arrhythmia, anti-diabetic cardiovascular complications, anti-tumor, anti-inflammatory, anti-bacterium, anti-virus, which would provide new core structures and new insights for new drug development in related fields.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
