4.7 Article Data Paper

Motor evoked potentials for multiple sclerosis, a multiyear follow-up dataset

Journal

SCIENTIFIC DATA
Volume 9, Issue 1, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41597-022-01335-0

Keywords

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Funding

  1. Research Foundation - Flanders (FWO)
  2. Flemish Government - department EWI
  3. Flemish Government
  4. Research Foundation-Flanders (FWO) [I002819N]
  5. Hermesfonds for ELIXIR Belgium [AH.2017.051, IO 17001306]

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Multiple sclerosis is a chronic disease affecting millions of people worldwide. Evoked potential measurements can be used to monitor the condition and provide decision support. The shared dataset includes thousands of clinical visits, providing metadata and data for exploring MS research and patient care.
Multiple sclerosis (MS) is a chronic disease affecting millions of people worldwide. Through the demyelinating and axonal pathology of MS, the signal conduction in the central nervous system is affected. Evoked potential measurements allow clinicians to monitor this process and can be used for decision support. We share a dataset that contains motor evoked potential (MEP) measurements, in which the brain is stimulated and the resulting signal is measured in the hands and feet. This results in time series of 100 milliseconds long. Typically, both hands and feet are measured in one hospital visit. The dataset contains 5586 visits of 963 patients, performed in day-to-day clinical care over a period of 6 years. The dataset consists of approximately 100,000 MEP. Clinical metadata such as the expanded disability status scale, sex, and age is also available. This dataset can be used to explore the role of evoked potentials in MS research and patient care. It may also be used as a benchmark for time series analysis and predictive modelling.

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