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Arshia Alimohammadi et al.
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James E. Siegler et al.
Summary: This narrative review summarizes the changing paradigms and latest data regarding the complex relationship between COVID-19 and cerebrovascular disease. Despite the association between COVID-19 and thrombotic complications, global declines in ischemic stroke and other cerebrovascular diseases have been observed, which may be attributed to patient avoidance of healthcare institutions and declines in other transmissible infectious illnesses.
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James E. Siegler et al.
Summary: COVID-19 is associated with a small but significant risk of cerebrovascular events, particularly ischemic stroke. The mortality rate is high for COVID-19-associated cerebrovascular complications, highlighting the importance of aggressive monitoring and early intervention.
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Tommaso Baldini et al.
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Maria E. Ramos-Araque et al.
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Mohamad Abdalkader et al.
Summary: COVID-19 infection can predispose patients to both arterial and venous thromboembolic events, including CVST. Reviewing the clinical and radiological presentation of CVST in COVID-19 positive patients revealed that patients often presented with symptoms like headache, fever, and gastrointestinal symptoms. Clinicians should be vigilant about the risk of acute CVST in patients positive for COVID-19.
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Ameena Rana et al.
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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
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Sherry H. -Y. Chou et al.
Summary: This study included patients with clinically diagnosed or laboratory-confirmed COVID-19 at 28 centers across 13 countries and 4 continents from March 1 to September 30, 2020. Neurological manifestations were prevalent among hospitalized patients with COVID-19 and were associated with higher in-hospital mortality. Patients with preexisting neurological disorders were at increased risk of developing neurological signs and/or syndromes in COVID-19.
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Vincent Raymaekers et al.
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ACTA NEUROLOGICA BELGICA
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Medicine, General & Internal
Mayte Sanchez van Kammen et al.
Summary: Cases of cerebral venous sinus thrombosis with thrombocytopenia have been reported following vaccination with AstraZeneca/Oxford and Janssen/Johnson & Johnson COVID-19 vaccines. A potential immune-mediated response involving platelet factor 4/heparin antibodies has been suggested as the underlying mechanism. This study found that baseline thrombocytopenia, heparin-induced thrombocytopenia, and platelet factor 4/heparin antibodies were uncommon in patients diagnosed with cerebral venous sinus thrombosis before the COVID-19 pandemic.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
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Maxime Taquet et al.
Summary: This study found that the incidence of cerebral venous thrombosis and portal vein thrombosis after a COVID-19 diagnosis was significantly higher than in cohorts of individuals who received mRNA vaccines or had influenza.
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Stefania Nannoni et al.
Summary: Acute cerebrovascular diseases occur in 1.4% of COVID-19 patients, with acute ischemic stroke being the most common manifestation. Patients with COVID-19 are more likely to have pre-existing vascular risk factors and higher mortality rates compared to those without cerebrovascular diseases.
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Moritz Seiffert et al.
CLINICAL RESEARCH IN CARDIOLOGY
(2020)
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Felix Nwajei et al.
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(2020)