4.6 Article

Case Report: Balo's Concentric Sclerosis-Like Lesion in a Patient With Relapsing-Remitting Multiple Sclerosis Treated With Dimethyl Fumarate

Journal

FRONTIERS IN NEUROLOGY
Volume 13, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fneur.2022.891113

Keywords

multiple sclerosis; dimethyl fumarate; Balo concentric sclerosis; MRI; Balo disease

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Balo's concentric sclerosis (BCS) is a rare demyelinating disorder with a debated connection to classic multiple sclerosis. Our report presents a case of a patient who developed a symptomatic Balo-like lesion following years of treatment for relapsing-remitting multiple sclerosis with dimethyl fumarate.
Balo's concentric sclerosis (BCS) is a rare demyelinating disorder characterized by acute or subacute neurological symptoms associated with characteristic lesions of concentric onion skin appearance on MRI images and in pathology. The connection between BCS and classic MS is still a subject of debates. Our report presents a case of a patient who developed a symptomatic Balo-like lesion following several years of classical relapsing-remitting multiple sclerosis treated with dimethyl fumarate.

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