4.6 Article

Diagnostic Yield and Complication Rate of Stereotactic Biopsies in Precision Medicine of Gliomas

Related references

Note: Only part of the references are listed.
Review Clinical Neurology

Complications after frame-based stereotactic brain biopsy: a systematic review

Maximilien Riche et al.

Summary: Stereotactic frame-based brain biopsy is a commonly used procedure for obtaining brain tissue, with complications being rare but potentially serious. Most complications present as neurological impairment, seizures, and bleeding.

NEUROSURGICAL REVIEW (2021)

Article Oncology

The TeloDIAG: how telomeric parameters can help in glioma rapid diagnosis and liquid biopsy approaches

P. Billard et al.

Summary: A new algorithm based on the C-circle assay was developed to identify telomere maintenance mechanisms in gliomas, leading to the proposal of a new classification tool, TeloDIAG, which defined five subtypes with potential implications for prognosis and treatment. This tool showed a high level of concordance with the World Health Organization classification and provided valuable insights into the molecular characteristics of gliomas, potentially influencing treatment decisions.

ANNALS OF ONCOLOGY (2021)

Article Oncology

EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood

Michael Weller et al.

Summary: The European Association of Neuro-Oncology (EANO) has released guidelines for the diagnosis, treatment, and follow-up of adult patients with diffuse gliomas, incorporating major changes in diagnostic algorithms based on the 2016 update of the WHO Classification of Tumors of the Central Nervous System, as well as evidence from recent large clinical trials.

NATURE REVIEWS CLINICAL ONCOLOGY (2021)

Article Oncology

Blood-Based Detection of BRAF V600E in Gliomas and Brain Tumor Metastasis

Keiko M. Kang et al.

Summary: The study developed a novel plasma-based ddPCR assay for detecting BRAF V600E mutations in patients with brain tumors and metastasis, demonstrating its potential as a diagnostic adjunct and monitoring tool for BRAF mutant gliomas and brain metastasis.

CANCERS (2021)

Article Genetics & Heredity

Intra-patient stability of tumor mutational burden from tissue biopsies at different time points in advanced cancers

Timothy V. Pham et al.

Summary: The study found that there was no significant difference in TMB between different tumor biopsies from the same patient, but TMB may increase in patients receiving ICI treatment. In general, tissue TMB remains stable over time, with specific therapies such as immunotherapy potentially leading to an increase in TMB.

GENOME MEDICINE (2021)

Review Oncology

Evidence-based recommendations on categories for extent of resection in diffuse glioma

Philipp Karschnia et al.

Summary: Surgical resection is the standard treatment for diffuse glioma, and the extent of tumor resection is associated with prognosis. Expert recommendations on different categories for extent of resection were developed based on evidence to standardize terminology. These categories may serve as a stratification factor for future clinical trials.

EUROPEAN JOURNAL OF CANCER (2021)

Article Oncology

PCV chemotherapy alone for WHO grade 2 oligodendroglioma: prolonged disease control with low risk of malignant progression

Jonathan Weller et al.

Summary: Chemotherapy with PCV alone is an effective treatment for WHO grade 2 oligodendroglioma, showing long progression-free survival and low rate of histological progression. In comparison to other treatment modalities such as TMZ or wait-and-scan, PCV demonstrated superior outcomes in terms of PFS and histological progression rate.

JOURNAL OF NEURO-ONCOLOGY (2021)

Article Oncology

Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas

Yao Yu et al.

Summary: The study found that hypermutation induced by temozolomide greatly increased the risk of high-grade disease recurrence in low-grade IDH-mutant glioma patients previously treated with TMZ, and was associated with shorter survival after transformation. Tumors with hypermutation were more likely to develop discontiguous foci of disease in the brain and spine.

NEURO-ONCOLOGY (2021)

Article Oncology

Interstitial Photodynamic Therapy Using 5-ALA for Malignant Glioma Recurrences

Stefanie Lietke et al.

Summary: Malignant glioma, especially in recurrent situations, has a poor prognosis. Interstitial photodynamic therapy (iPDT) using 5-aminolevulinic acid-induced protoporphyrin IX as a cytotoxic photosensitizer shows promising results in treating recurrent malignant gliomas. Heterogeneous treatment response was observed without significant association with patient characteristics, treatment-related factors, or molecular markers. Further prospective evaluation is needed to identify mechanisms and prognostic factors of favorable treatment response.

CANCERS (2021)

Article Medicine, General & Internal

Low Detection Rate of H3K27M Mutations in Cerebrospinal Fluid Obtained from Lumbar Puncture in Newly Diagnosed Diffuse Midline Gliomas

Jotaro On et al.

Summary: Recent studies have shown the feasibility of detecting H3K27M mutations in diffuse midline glioma patients' cerebrospinal fluid. However, liquid biopsy only achieved a definitive detection of the mutation in a small percentage of patients. Younger age and higher concentration of CSF protein tended to be associated with cases where a definitive assessment was possible.

DIAGNOSTICS (2021)

Article Medicine, Research & Experimental

Fragmentation patterns and personalized sequencing of cell-free DNA in urine and plasma of glioma patients

Florent Mouliere et al.

Summary: The study focused on detecting glioma-derived cell-free DNA (cfDNA) in body fluids and found that tumor-derived DNA could be identified in the majority of CSF, plasma, and urine samples with different tumor fractions. They also discovered a significant difference in cfDNA fragment sizes between glioma patients and individuals with non-malignant brain disorders or healthy individuals, which could potentially aid in non-invasive cancer detection using machine learning models.

EMBO MOLECULAR MEDICINE (2021)

Review Oncology

Clinical outcomes as a function of the number of samples taken during stereotactic needle biopsies: a meta-analysis

Sanjay Dhawan et al.

Summary: The study found a non-linear association between the number of biopsy samples taken during stereotactic needle biopsy and morbidity risk. However, there was no association between the number of samples taken and diagnostic yield or mortality.

JOURNAL OF NEURO-ONCOLOGY (2021)

Review Oncology

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary

David N. Louis et al.

Summary: The fifth edition of the WHO Classification of Tumors of the Central Nervous System integrates molecular diagnostics into CNS tumor classification, introduces different approaches to tumor nomenclature and grading, and emphasizes the importance of integrated diagnoses and layered reports.

NEURO-ONCOLOGY (2021)

Article Oncology

Liquid Biopsy in Glioblastoma Management: From Current Research to Future Perspectives

Lidia Gatto et al.

Summary: Glioblastoma is the most common primary tumor of the central nervous system, characterized by challenges and limitations. Liquid biopsy offers an attractive minimally invasive solution to support glioblastoma management at different stages.

ONCOLOGIST (2021)

Article Oncology

Circulating Biomarkers in Glioblastoma Ready for Prime Time?

Dimitrios Mathios et al.

Summary: Liquid biopsy approaches have been utilized in oncology for detection of circulating biomarkers, but there has been little progress in implementing these approaches for detection of brain tumors. The clinical implementation of circulating biomarkers for brain tumors remains a challenge despite recent methodological improvements.

CANCER JOURNAL (2021)

Article Radiology, Nuclear Medicine & Medical Imaging

TSPO PET, tumour grading and molecular genetics in histologically verified glioma: a correlative 18F-GE-180 PET study

M. Unterrainer et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2020)

Review Oncology

Molecular imaging and advanced MRI findings following immunotherapy in patients with brain tumors

Norbert Galldiks et al.

EXPERT REVIEW OF ANTICANCER THERAPY (2020)

Article Multidisciplinary Sciences

Mechanisms and therapeutic implications of hypermutation in gliomas

Mehdi Touat et al.

NATURE (2020)

Article Multidisciplinary Sciences

The integrated genomic and epigenomic landscape of brainstem glioma

Lee H. Chen et al.

NATURE COMMUNICATIONS (2020)

Review Biotechnology & Applied Microbiology

The surgical perspective in precision treatment of diffuse gliomas

Niklas Thon et al.

ONCOTARGETS AND THERAPY (2019)

Article Oncology

Defining EGFR amplification status for clinical trial inclusion

Pim J. French et al.

NEURO-ONCOLOGY (2019)

Article Clinical Neurology

Increasing the diagnostic yield of stereotactic brain biopsy using intraoperative histological smear

Bertrand Mathon et al.

CLINICAL NEUROLOGY AND NEUROSURGERY (2019)

Article Radiology, Nuclear Medicine & Medical Imaging

Joint EANM/EANO/RANO practice guidelines/SNMMI procedure standards for imaging of gliomas using PET with radiolabelled amino acids and [18F]FDG: version 1.0

Ian Law et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2019)

Article Clinical Neurology

Resection of gliomas deemed inoperable by neurosurgeons based on preoperative imaging studies

Derek G. Southwell et al.

JOURNAL OF NEUROSURGERY (2018)

Article Multidisciplinary Sciences

DNA methylation-based classification of central nervous system tumours

David Capper et al.

NATURE (2018)

Article Multidisciplinary Sciences

The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma

Bill H. Diplas et al.

NATURE COMMUNICATIONS (2018)

Review Oncology

Response Assessment in Neuro-Oncology Clinical Trials

Patrick Y. Wen et al.

JOURNAL OF CLINICAL ONCOLOGY (2017)

Article Multidisciplinary Sciences

Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma

Brett E. Johnson et al.

SCIENCE (2014)

Article Clinical Neurology

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma

Marc Remke et al.

ACTA NEUROPATHOLOGICA (2013)

Article Biochemistry & Molecular Biology

The Somatic Genomic Landscape of Glioblastoma

Cameron W. Brennan et al.

Article Medicine, General & Internal

Comparison of a Strategy Favoring Early Surgical Resection vs a Strategy Favoring Watchful Waiting in Low-Grade Gliomas

Asgeir S. Jakola et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)

Article Clinical Neurology

Frameless robotically targeted stereotactic brain biopsy: feasibility, diagnostic yield, and safety

Kimon Bekelis et al.

JOURNAL OF NEUROSURGERY (2012)

Article Clinical Neurology

Evaluation of brain biopsy in the diagnosis of severe neurologic disease of unknown etiology

Joseph D. Burns et al.

CLINICAL NEUROLOGY AND NEUROSURGERY (2009)

Article Clinical Neurology

Stereotactic brain biopsy: Single center retrospective analysis of complications

Ching-Chang Chen et al.

CLINICAL NEUROLOGY AND NEUROSURGERY (2009)

Article Clinical Neurology

Safety and efficacy of frameless and frame-based intracranial biopsy techniques

R. Dammers et al.

ACTA NEUROCHIRURGICA (2008)

Article Clinical Neurology

Complications in 622 cases of frame-based stereotactic biopsy, a decreasing procedure

Paul N. Kongkham et al.

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES (2008)