Journal
FRONTIERS IN IMMUNOLOGY
Volume 13, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2022.908010
Keywords
Lactobacillus; respiratory diseases; the gut-lung axis; mucosal immunity; safety
Categories
Funding
- National Natural Science Foundation of China [31970177]
- National Natural Science Foundation of Hunan Province [2021JJ40475]
Ask authors/readers for more resources
Lactobacillus, as a natural immunobiotic, has been shown to have beneficial effects in alleviating respiratory diseases. The efficacy of Lactobacillus may be influenced by factors such as strain and host background. This article summarizes the mechanism and safety of Lactobacillus in regulating respiratory immunity.
Respiratory diseases cause a high incidence and mortality worldwide. As a natural immunobiotic, Lactobacillus has excellent immunomodulatory ability. Administration of some Lactobacillus species can alleviate the symptoms of respiratory diseases such as respiratory tract infections, asthma, lung cancer and cystic fibrosis in animal studies and clinical trials. The beneficial effect of Lactobacillus on the respiratory tract is strain dependent. Moreover, the efficacy of Lactobacillus may be affected by many factors, such as bacteria dose, timing and host background. Here, we summarized the beneficial effect of administered Lactobacillus on common respiratory diseases with a focus on the mechanism and safety of Lactobacillus in regulating respiratory immunity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available