4.8 Article

Splenic Dendritic Cells and Macrophages Drive B Cells to Adopt a Plasmablast Cell Fate

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Notch2-mediated plasticity between marginal zone and follicular B cells

Markus Lechner et al.

Summary: FoB and MZB cells are functionally distinct mature B cell populations in the spleen, which can be re-programmed through Notch2 activation. The study demonstrates plasticity between these cell types and suggests a potential pathway for MZB cell development in vivo, driven by a singular signaling event.

NATURE COMMUNICATIONS (2021)

Article Cell Biology

Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans

Henry J. Sutton et al.

Summary: Using single-cell RNA sequencing, researchers explored the diversity of human B cells in healthy individuals and those exposed to malaria, identifying two distinct lineages with atypical B cells being part of the alternative lineage. Upon malaria vaccination, the alternative lineage cells respond to initial immunization and booster doses, but develop an atypical phenotype with repeated boosts, indicating that atypical cells are a normal component of healthy immune responses.

CELL REPORTS (2021)

Article Multidisciplinary Sciences

Marginal zone SIGN-R1+ macrophages are essential for the maturation of germinal center B cells in the spleen

Gabriela Pirgova et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Biochemistry & Molecular Biology

Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates

Charlotte Viant et al.

Review Immunology

Structure and function of the immune system in the spleen

Steven M. Lewis et al.

SCIENCE IMMUNOLOGY (2019)

Article Multidisciplinary Sciences

Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes

Imogen Moran et al.

NATURE COMMUNICATIONS (2018)

Article Immunology

Regulated selection of germinal-center cells into the memory B cell compartment

Ryo Shinnakasu et al.

NATURE IMMUNOLOGY (2016)

Article Biochemistry & Molecular Biology

Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

Andrew S. Ishizuka et al.

NATURE MEDICINE (2016)

Review Immunology

Targeting dendritic cells: a promising strategy to improve vaccine effectiveness

Christophe Macri et al.

CLINICAL & TRANSLATIONAL IMMUNOLOGY (2016)

Article Multidisciplinary Sciences

Apoptosis and antigen affinity limit effector cell differentiation of a single naive B cell

Justin J. Taylor et al.

SCIENCE (2015)

Review Microbiology

Antibody and B cell responses to Plasmodium sporozoites

Johanna N. Dups et al.

FRONTIERS IN MICROBIOLOGY (2014)

Article Immunology

Evolution of B Cell Responses to Clec9A-Targeted Antigen

Hae-Young Park et al.

JOURNAL OF IMMUNOLOGY (2013)

Review Immunology

Tissue-resident macrophages

Luke C. Davies et al.

NATURE IMMUNOLOGY (2013)

Review Immunology

Boosting antibody responses by targeting antigens to dendritic cells

Irina Caminschi et al.

TRENDS IN IMMUNOLOGY (2012)

Article Immunology

Correlates of vaccine-induced immunity

Stanley A. Plotkin

CLINICAL INFECTIOUS DISEASES (2008)

Article Immunology

High affinity germinal center B cells are actively selected into the plasma cell compartment

Tri Giang Phan et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2006)

Article Biochemistry & Molecular Biology

Quantitative imaging of Plasmodium transmission from mosquito to mammal

R Amino et al.

NATURE MEDICINE (2006)

Article Immunology

Histological analysis of CD11c-DTR/GFP mice after in vivo depletion of dendritic cells

HC Probst et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2005)

Review Immunology

Mouse and human dendritic cell subtypes

K Shortman et al.

NATURE REVIEWS IMMUNOLOGY (2002)

Article Multidisciplinary Sciences

B cells acquire antigen from target cells after synapse formation

FD Batista et al.

NATURE (2001)

Article Immunology

CD8+ but not CD8- dendritic cells cross-prime cytotoxic T cells in vivo

JMM den Haan et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2000)