4.8 Review

The Role of the Gut Microbiota in the Development of Ischemic Stroke

Journal

FRONTIERS IN IMMUNOLOGY
Volume 13, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2022.845243

Keywords

ischemic stroke; gut microbiota; gut-brain axis communication; neuro inflammation; fecal microbiota transplantation

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Funding

  1. National Natural Science Foundation of China [82171336, 81870939]
  2. Health Commission of Jiangxi Provincial [202130032]

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This review summarizes the studies on the gut microbiota and its relationship with various neurological diseases, focusing on ischemic stroke. The review provides novel ideas for the prevention and treatment of ischemic stroke by exploring the physiological function of the gut microbiota and gut microbiota disorders related to the central nervous system.
An increasing number of studies have focused on the gut microbiota and its relationship with various neurological diseases. The gut microbiota can affect the metabolic status of the body, in addition to having an important impact on blood pressure, blood glucose, and atherosclerosis, all of which are risk factors for ischemic stroke. In this review, we summarized studies that included the physiological function of the gut microbiota and gut microbiota disorders related to the central nervous system, thus providing novel ideas for the prevention and treatment of ischemic stroke.

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