4.6 Article

Dose-Area Product Determination and Beam Monitor Calibration for the Fixed Beam of the Shanghai Advanced Proton Therapy Facility

Journal

APPLIED SCIENCES-BASEL
Volume 12, Issue 9, Pages -

Publisher

MDPI
DOI: 10.3390/app12094111

Keywords

dose-area product; reference dosimetry; proton beam; beam monitor calibration

Funding

  1. National Key Research and Development Program [2016YFC0105406]
  2. National Natural Science Foundation of China [61571262, 11575095, 61171115]

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This paper proposes a machine log file based reconstruction method to calculate the field uniformity for proton field analysis. The study compares and analyzes the differences in DAP determined using different devices. The consistency of the two methods used to determine DAP and calibrate beam monitor is verified by analyzing the delivered dose.
Research conducted to-date, makes use of the IBA-Lynx scintillating screen and radiochromic film to analyze the proton field uniformity for dose-area product (DAP) determination. In this paper, the machine log file based reconstruction is proposed to calculate the field uniformity to simplify the measurement. In order to calculate the field uniformity, the dose distribution is reconstructed based on the machine log file with matRad (an open source software for analytical dose calculation in MATLAB). After acquisition of the dose distribution, the field flatness and symmetry are calculated automatically for different proton energies. A comprehensive comparison of DAP determined with Bragg peak chamber (BPC) and Markus chamber (MC) is presented. The actual delivered dose is reconstructed with the log file to analyze the lateral dose distribution of the scanned field. DAP of different energies are calculated ranging from 70.6 MeV to 235 MeV. The percentage difference is calculated, illustrating the DAP discrepancy between the MC and BPC to the mean value. The percentage difference ranges from -0.19% to 1.26%. The variation between DAP measured with the BPC and MC peaks at -2.5%. The log file based reconstruction to calculate field uniformity can be an alternative for DAP determination. The direct method using a large-area Bragg peak chamber is investigated. The two methods to determine DAP and calibrate beam monitor illustrate consistent results.

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