4.7 Article

Nanomaterial Exposure, Extracellular Vesicle Biogenesis and Adverse Cellular Outcomes: A Scoping Review

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

Extracellular Vesicles Mediate the Intercellular Exchange of Nanoparticles

Xian Wu et al.

Summary: This study develops a collagen-based three-dimension assay to quantify and understand the intercellular exchange of nanoparticles (NPs). The results demonstrate the significant role of extracellular vesicles (EVs) in NP transport, providing insights into the importance of EVs in NP delivery into complex tissues.

ADVANCED SCIENCE (2022)

Review Mathematical & Computational Biology

Novel biomarker and drug delivery systems for theranostics - extracellular vesicles

Ewa L. Stepien et al.

Summary: Extracellular vesicles (EVs) are nano- and micro-sized double-layered membrane entities derived from most cell types and released into biological fluids. Recent advances in the field of EVs and developments of new imaging methods have revealed benefits of radiolabeled EVs in diagnostic and interventional medicine as a potential drug delivery system in theranostics.

BIO-ALGORITHMS AND MED-SYSTEMS (2022)

Article Nanoscience & Nanotechnology

Platinum Nanoparticles Enhance Exosome Release in Human Lung Epithelial Adenocarcinoma Cancer Cells (A549): Oxidative Stress and the Ceramide Pathway are Key Players

Sangiliyandi Gurunathan et al.

Summary: Several studies have demonstrated the molecular mechanisms involved in the biogenesis and release of exosomes. PtNPs were shown to enhance exosome secretion in A549 cells by inducing oxidative stress and the ceramide pathway. Pre-treatment with NAC could inhibit the PtNPs-induced exosome biogenesis and release.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Review Chemistry, Multidisciplinary

Engineered Tools to Study Intercellular Communication

Benjamin A. Yang et al.

Summary: Multicellular organisms rely on intercellular communication networks to maintain homeostasis, and studying this communication is crucial for disease prevention, aging, and therapeutic development. Recent advances in microengineering and high-throughput genomics provide new ways to study cellular interactions.

ADVANCED SCIENCE (2021)

Article Materials Science, Multidisciplinary

Effect of multi-functional polyhydroxylated polyhedral oligomeric silsesquioxane (POSS) nanoparticles on the angiogenesis and exosome biogenesis in human umbilical vein endothelial cells (HUVECs)

Maryam Feghhi et al.

Summary: The study found that treatment of HUVECs with POH-POSS NPs enhanced angiogenesis and exosome biogenesis, leading to increased cell survival rate, healing rate, and gene expression.

MATERIALS & DESIGN (2021)

Review Nanoscience & Nanotechnology

A Comprehensive Review on Factors Influences Biogenesis, Functions, Therapeutic and Clinical Implications of Exosomes

Sangiliyandi Gurunathan et al.

Summary: Exosomes are nanoscale membrane vesicles secreted by cells, which play important roles in intercellular communication and disease diagnosis. Research on exosomes has great potential in biomedical fields, but the underlying biological mechanisms require further exploration.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Article Materials Science, Biomaterials

Biogenesis of Extracellular Vesicles Produced from Human-Stem-Cell-Derived Cortical Spheroids Exposed to Iron Oxides

Mark Marzano et al.

Summary: The research utilized iron oxide nanoparticles to label stem cells or extracellular vesicles for imaging. Results showed that the nanoparticles had little impact on the metabolic activity of neural progenitor cells, and affected the biogenesis of extracellular vesicles.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2021)

Article Chemistry, Physical

Shedding plasma membrane vesicles induced by graphene oxide nanoflakes in brain cultured astrocytes

Mattia Musto et al.

Summary: Microvesicles generated by astrocytes play a crucial role in intercellular communication, modulating neuronal functions. By utilizing nanotechnology and unconventional tools, deeper understanding of these glial signals can be achieved.

CARBON (2021)

Article Nanoscience & Nanotechnology

Palladium Nanoparticle-Induced Oxidative Stress, Endoplasmic Reticulum Stress, Apoptosis, and Immunomodulation Enhance the Biogenesis and Release of Exosome in Human Leukemia Monocytic Cells (THP-1)

Sangiliyandi Gurunathan et al.

Summary: This study demonstrates for the first time that PdNPs stimulate exosome biogenesis and release in THP-1 cells, simultaneously increasing levels of cytokines and chemokines by modulating various physiological processes. These findings offer a rational approach to enhancing exosome production for various therapeutic applications.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Review Biochemistry & Molecular Biology

Extracellular Vesicles and Thrombosis: Update on the Clinical and Experimental Evidence

Konstantinos Zifkos et al.

Summary: Extracellular vesicles (EVs) are an important mechanism for intercellular communication and exchange of molecules, playing crucial roles in both physiological and pathological situations as well as in clot formation and resolution. They have potential implications as biomarkers and therapeutic vectors in arterial and venous thrombosis.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Cell Biology

Biodistribution of extracellular vesicles following administration into animals: A systematic review

Matthew Kang et al.

Summary: The biodistribution of EVs in recipient animals is time-dependent, with small-EVs mostly abundant in the liver and large-EVs primarily present in the lungs. Detection peaked in the liver and kidneys within the first hour, while distribution to the lungs and spleen peaked between 2-12 hours. Standardized guidelines are recommended to reduce variability in methodology in future EV biodistribution studies.

JOURNAL OF EXTRACELLULAR VESICLES (2021)

Article Nanoscience & Nanotechnology

Nano-Sized Hydroxyapatite Induces Apoptosis and Osteogenic Differentiation of Vascular Smooth Muscle Cells via JNK/c-JUN Pathway

Qi Liu et al.

Summary: The study demonstrated that nanosized hydroxyapatite (nHAp) promotes osteogenic transformation of vascular smooth muscle cells (VSMCs) through the activation of the JNK/c-JUN signaling pathway, leading to cell apoptosis and vascular calcification (VC) progression.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Review Cell & Tissue Engineering

Innate Immunity Communicates Using the Language of Extracellular Microvesicles

Mariusz Z. Ratajczak et al.

Summary: The innate immunity system and extracellular microvesicles (ExMVs) have been present since early in the evolution of life, and have a shared language for communication which influences immune and inflammation responses. ExMVs directly impact cellular functions and interact with soluble components of the innate immunity system, potentially activating other immune pathways such as the complement cascade.

STEM CELL REVIEWS AND REPORTS (2021)

Article Medicine, Research & Experimental

Extracellular Vesicles and Metastasis

Shizhen Emily Wang

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2020)

Review Environmental Sciences

Mitochondrial toxicity of nanomaterials

Daming Wu et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2020)

Review Biotechnology & Applied Microbiology

Extracellular Vesicles Derived From Mesenchymal Stem Cells (MSC) in Regenerative Medicine: Applications in Skin Wound Healing

Antonio Casado-Diaz et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

Article Environmental Sciences

Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation

Di Wang et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2020)

Article Biotechnology & Applied Microbiology

The Fate of SWCNTs in Mouse Peritoneal Macrophages: Exocytosis, Biodegradation, and Sustainable Retention

Ping-Xuan Dong et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

Review Pharmacology & Pharmacy

Macrophage M1/M2 polarization

Chen Yunna et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2020)

Article Pharmacology & Pharmacy

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

Nathalie Percie du Sert et al.

BRITISH JOURNAL OF PHARMACOLOGY (2020)

Review Endocrinology & Metabolism

The Role of Extracellular Vesicles in β-Cell Function and Viability: A Scoping Review

Stephanie Chidester et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Review Immunology

Extracellular Vesicles in Viral Infections: Two Sides of the Same Coin?

Sharon de Toledo Martins et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)

Review Neurosciences

Exosomes as a new pain biomarker opportunity

Simona D'Agnelli et al.

MOLECULAR PAIN (2020)

Article Materials Science, Biomaterials

In situ self-assembled Ag-Fe3O4 nanoclusters in exosomes for cancer diagnosis

Tayyaba et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

Review Pharmacology & Pharmacy

Extracellular Vesicles as Drug Delivery Systems - Methods of Production and Potential Therapeutic Applications

Magdalena Surman et al.

CURRENT PHARMACEUTICAL DESIGN (2019)

Article Cell & Tissue Engineering

The skin regeneration potential of a pro-angiogenic secretome from human skin-derived multipotent stromal cells

Anny Waloski Robert et al.

JOURNAL OF TISSUE ENGINEERING (2019)

Article Pharmacology & Pharmacy

Human primary macrophages scavenge AuNPs and eliminate it through exosomes. A natural shuttling for nanomaterials

Mariantonia Logozzi et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)

Review Cell Biology

Advances in therapeutic applications of extracellular vesicles

Oscar P. B. Wiklander et al.

SCIENCE TRANSLATIONAL MEDICINE (2019)

Review Pharmacology & Pharmacy

Targeting Synaptic Plasticity in Experimental Models of Alzheimer's Disease

Dalila Mango et al.

FRONTIERS IN PHARMACOLOGY (2019)

Article Biophysics

Calcium phosphate particles stimulate exosome secretion from phagocytes for the enhancement of drug delivery

Yan-Jye Shyong et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2018)

Review Oncology

Toxicity of engineered nanomaterials mediated by nano-bio-eco interactions

Xiaojia He et al.

JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS (2018)

Review Immunology

Exosome and mesenchymal stem cell cross-talk in the tumor microenvironment

Theresa L. Whiteside

SEMINARS IN IMMUNOLOGY (2018)

Article Chemistry, Multidisciplinary

Exosomal miRNA Profiling to Identify Nanoparticle Phagocytic Mechanisms

Lin Zhang et al.

SMALL (2018)

Article Medicine, Research & Experimental

Circulating ectosomes: Determination of angiogenic microRNAs in type 2 diabetes

Ewa L. Stepien et al.

THERANOSTICS (2018)

Article Medicine, General & Internal

PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation

Andrea C. Tricco et al.

ANNALS OF INTERNAL MEDICINE (2018)

Review Biochemistry & Molecular Biology

Toxicological status of nanoparticles: What we know and what we don't know

Wided N. Missaoui et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2018)

Review Biochemistry & Molecular Biology

Current knowledge on exosome biogenesis and release

Nina Pettersen Hessvik et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Review Oncology

Ribosome biogenesis in cancer: new players and therapeutic avenues

Joffrey Pelletier et al.

NATURE REVIEWS CANCER (2018)

Review Oncology

Circulating microRNAs and extracellular vesicles as potential cancer biomarkers: a systematic review

Juntaro Matsuzaki et al.

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2017)

Review Cell Biology

Markers and Biomarkers of Endothelium: When Something Is Rotten in the State

Nikolay V. Goncharov et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)

Article Biotechnology & Applied Microbiology

LncRNA MEG3 enhances cisplatin sensitivity in non-small cell lung cancer by regulating miR-21-5p/SOX7 axis

Pei Wang et al.

ONCOTARGETS AND THERAPY (2017)

Review Pharmacology & Pharmacy

Biological responses to nanomaterials: understanding nano-bio effects on cell behaviors

Xi-Qiu Liu et al.

DRUG DELIVERY (2017)

Article Endocrinology & Metabolism

Calcium Phosphate Crystals from Uremic Serum Promote Osteogenic Differentiation in Human Aortic Smooth Muscle Cells

Yaorong Liu et al.

CALCIFIED TISSUE INTERNATIONAL (2016)

Review Biochemistry & Molecular Biology

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

Mercedes Tkach et al.

Review Food Science & Technology

Nanotechnology in food science: Functionality, applicability, and safety assessment

Xiaojia He et al.

JOURNAL OF FOOD AND DRUG ANALYSIS (2016)

Article Cell Biology

Cell Signaling and Stress Responses

Gokhan S. Hotamisligil et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)

Review Medicine, General & Internal

Rayyan-a web and mobile app for systematic reviews

Mourad Ouzzani et al.

SYSTEMATIC REVIEWS (2016)

Review Chemistry, Medicinal

Metal Oxide Nanomaterials in Nanomedicine: Applications in Photodynamic Therapy and Potential Toxicity

Xiaojia He et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2015)

Article Biochemistry & Molecular Biology

The Economics of Reproducibility in Preclinical Research

Leonard P. Freedman et al.

PLOS BIOLOGY (2015)

Article Biotechnology & Applied Microbiology

Cellular communication via nanoparticle-transporting biovesicles

Silvia Ferrati et al.

NANOMEDICINE (2014)

Editorial Material Cardiac & Cardiovascular Systems

Vascular Calcification: An Age-Old Problem of Old Age

Jane A. Leopold

CIRCULATION (2013)

Article Health Care Sciences & Services

Testing the Newcastle Ottawa Scale showed low reliability between individual reviewers

Lisa Hartling et al.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2013)

Article Pharmacology & Pharmacy

Effects of subtoxic concentrations of TiO2 and ZnO nanoparticles on human lymphocytes, dendritic cells and exosome production

Britta Andersson-Willman et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2012)

Article Health Care Sciences & Services

Scoping studies: advancing the methodology

Danielle Levac et al.

IMPLEMENTATION SCIENCE (2010)

Article Toxicology

ToxRTool, a new tool to assess the reliability of toxicological data

Klaus Schneider et al.

TOXICOLOGY LETTERS (2009)

Article Physics, Fluids & Plasmas

Finding community structure in very large networks

A Clauset et al.

PHYSICAL REVIEW E (2004)

Article Multidisciplinary Sciences

Calcification in atherosclerosis: Bone biology and chronic inflammation at the arterial crossroads

TM Doherty et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)