Journal
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
Volume -, Issue 181, Pages -Publisher
JOURNAL OF VISUALIZED EXPERIMENTS
DOI: 10.3791/63534
Keywords
-
Categories
Funding
- Semmelweis University, Budapest, Hungary
- Hungarian Human Resources Development Operational Program [EFOP-3.6.2-16-2017-00006]
- Ministry for Innovation and Technology in Hungary
Ask authors/readers for more resources
Open spinal cord injury techniques often involve invasive procedures and take a long time. This new technique eliminates the need for laminectomy, making it faster and less burdensome for animals. By removing two spinous processes and tilting the caudal vertebral arch, the surgical area opens up for lateral hemisection, minimizing trauma and bone wounds.
Open spinal cord injury techniques modeling laceration-like injuries are time-consuming and invasive because they involve laminectomy. This new technique eliminates laminectomy by removing two spinous processes and lifting, then tilting the caudal vertebral arch. The surgical area opens up without the need for laminectomy. Lateral hemisection is then performed with direct visible control under a microscope. The trauma is minimized, requiring only a small bone wound. This technique has several advantages: it is faster and, therefore, less of a burden for the animal, and the bone wound is smaller. Because the laminectomy is eliminated, there is less chance for unwanted injury to the spinal cord, and there are no bone splinters that can cause problems (bone splinters embedded in the spinal cord can cause swelling and secondary damage). The vertebral canal remains intact. The main limitation is that the hemisection can only be performed in the intervertebral spaces. The results show that this technique can be performed much faster than the traditional surgical approach, using laminectomy (11 min vs. 35 min). This technique can be useful for researchers working with animal models of open spinal cord injury as it is widely adaptable and does not require any additional specialized instrumentation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available