4.6 Review

Synapse Formation and Function Across Species: Ancient Roles for CCP, CUB, and TSP-1 Structural Domains

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development

Jie Wang et al.

Summary: RTN4 receptors and BAI adhesion-GPCRs were found to have high affinity interaction facilitated by unusual glycoconjugates, regulating neural network activity.
Article Biochemistry & Molecular Biology

C1QL3 promotes cell-cell adhesion by mediating complex formation between ADGRB3/BAI3 and neuronal pentraxins

Matthew J. Sticco et al.

Summary: Synapses are the key structures through which neurons communicate, regulated by a variety of proteins. C1QL proteins, part of the C1q superfamily, act as synaptic organizers involved in crucial neuronal processes. The study shows that C1QL3 mediates a novel cell-cell adhesion complex involving ADGRB3 and two neuronal pentraxins, suggesting the formation of a new trans-synaptic adhesion complex.

FASEB JOURNAL (2021)

Article Biology

Sushi domain-containing protein 4 controls synaptic plasticity and motor learning

Ines Gonzalez-Calvo et al.

Summary: The study revealed the importance of Susd4 gene in synaptic function and plasticity, with its constitutive loss affecting motor coordination adaptation and learning in mice. Additionally, SUSD4 was found to interact with proteins regulating AMPA receptor turnover, potentially playing a role in neurodevelopmental diseases.

ELIFE (2021)

Article Psychiatry

Reduced hippocampal inhibition and enhanced autism-epilepsy comorbidity in mice lacking neuropilin 2

Carol Eisenberg et al.

Summary: Neuropilin 2 (Nrp2) deficiency in mice leads to reduced numbers of interneuron subtypes in the hippocampus and compromised inhibition in CA1, increasing susceptibility to seizures and exhibiting behavioral deficits consistent with ASD/epilepsy phenotype.

TRANSLATIONAL PSYCHIATRY (2021)

Article Biochemistry & Molecular Biology

Extracellular Matrix Muscle Arm Development Defective Protein Cooperates with the One Immunoglobulin Domain Protein To Suppress Precocious Synaptic Remodeling

Chunhong Chen et al.

Summary: The study revealed that muscle arm development defective protein-4 (MADD-4) cooperates with one immunoglobulin domain protein-1 (OIG-1) to delay the occurrence of DD synaptic remodeling in nematodes, demonstrating a novel role for the extracellular matrix in synaptic plasticity. This sheds light on the molecular mechanisms involved in dorsal D-type (DD) synaptic remodeling, particularly in the role of MADD-4 in the process.

ACS CHEMICAL NEUROSCIENCE (2021)

Article Cell Biology

The HSPG syndecan is a core organizer of cholinergic synapses

Xin Zhou et al.

Summary: The study demonstrates the crucial role of syndecan SDN-1 in regulating the clustering and content of acetylcholine receptors at synapses.

JOURNAL OF CELL BIOLOGY (2021)

Review Biochemistry & Molecular Biology

Synaptic Specificity, Recognition Molecules, and Assembly of Neural Circuits

Joshua R. Sanes et al.

Review Biochemistry & Molecular Biology

The Evolutionary Assembly of Neuronal Machinery

Detlev Arendt

CURRENT BIOLOGY (2020)

Article Multidisciplinary Sciences

A brainwide atlas of synapses across the mouse life span

Melissa Cizeron et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

The auxiliary glutamate receptor subunit dSol-1 promotes presynaptic neurotransmitter release and homeostatic potentiation

Beril Kiragasi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Neurosciences

Kainate receptor auxiliary subunit NETO2 is required for normal fear expression and extinction

Marie Mennesson et al.

NEUROPSYCHOPHARMACOLOGY (2019)

Article Multidisciplinary Sciences

Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing

Margarita C. Dinamarca et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

Revisiting the classification of adhesion GPCRs

Nicole Scholz et al.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2019)

Review Neurosciences

The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function

James W. Fawcett et al.

NATURE REVIEWS NEUROSCIENCE (2019)

Article Biochemistry & Molecular Biology

Biallelic intragenic duplication in ADGRB3 (BAI3) gene associated with intellectual disability, cerebellar atrophy, and behavioral disorder

Carmela Scuderi et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2019)

Review Anatomy & Morphology

Shaping Synapses by the Neural Extracellular Matrix

Maura Ferrer-Ferrer et al.

FRONTIERS IN NEUROANATOMY (2018)

Review Genetics & Heredity

Immunoglobulin-Like Receptors and Their Impact on Wiring of Brain Synapses

Scott Cameron et al.

ANNUAL REVIEW OF GENETICS, VOL 52 (2018)

Article Neurosciences

Architecture of the Mouse Brain Synaptome

Fei Zhu et al.

NEURON (2018)

Review Neurosciences

Neural immunoglobulin superfamily interaction networks

Kai Zinn et al.

CURRENT OPINION IN NEUROBIOLOGY (2017)

Article Biochemistry & Molecular Biology

Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts

Ken H. Loh et al.

Article Biochemistry & Molecular Biology

Metal Ion-dependent Heavy Chain Transfer Activity of TSG-6 Mediates Assembly of the Cumulus-Oocyte Matrix

David C. Briggs et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Medicine, Research & Experimental

BAI1 regulates spatial learning and synaptic plasticity in the hippocampus

Dan Zhu et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Article Neurosciences

The Susd2 protein regulates neurite growth and excitatory synaptic density in hippocampal cultures

Yann Nadjar et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2015)

Article Multidisciplinary Sciences

Functional reconstitution of Drosophila melanogaster NMJ glutamate receptors

Tae Hee Han et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Neurosciences

Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear

Diana Mendus et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2014)

Article Biochemistry & Molecular Biology

Proteolytic Processing of the Extracellular Scaffolding Protein LEV-9 Is Required for Clustering Acetylcholine Receptors

Luis Briseno-Roa et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

C. elegans Punctin specifies cholinergic versus GABAergic identity of postsynaptic domains

Berangere Pinan-Lucarre et al.

NATURE (2014)

Article Biochemistry & Molecular Biology

Brain-specific Angiogenesis Inhibitor-1 Signaling, Regulation, and Enrichment in the Postsynaptic Density

Jason R. Stephenson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Neurosciences

Differential Control of Thrombospondin over Synaptic Glycine and AMPA Receptors in Spinal Cord Neurons

Laetitia Hennekinne et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Neurosciences

Modulation of homomeric and heteromeric kainate receptors by the auxiliary subunit Neto1

Janet L. Fisher et al.

JOURNAL OF PHYSIOLOGY-LONDON (2013)

Article Biochemistry & Molecular Biology

The adhesion-GPCR BAI3, a gene linked to psychiatric disorders, regulates dendrite morphogenesis in neurons

V. Lanoue et al.

MOLECULAR PSYCHIATRY (2013)

Article Neurosciences

Synaptic scaffold evolution generated components of vertebrate cognitive complexity

Jess Nithianantharajah et al.

NATURE NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

Neto2 is a KCC2 interacting protein required for neuronal Cl- regulation in hippocampal neurons

Evgueni A. Ivakine et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Neurosciences

The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease

Alexander H. Stephan et al.

ANNUAL REVIEW OF NEUROSCIENCE, VOL 35 (2012)

Article Biochemistry & Molecular Biology

Whole-Genome Sequencing in Autism Identifies Hot Spots for De Novo Germline Mutation

Jacob J. Michaelson et al.

Review Biochemistry & Molecular Biology

Thrombospondins as key regulators of synaptogenesis in the central nervous system

W. Christopher Risher et al.

MATRIX BIOLOGY (2012)

Article Multidisciplinary Sciences

Sushi domains confer distinct trafficking profiles on GABAB receptors

Saad Hannan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Neurosciences

Cbln1 and its family proteins in synapse formation and maintenance

Michisuke Yuzaki

CURRENT OPINION IN NEUROBIOLOGY (2011)

Article Biochemistry & Molecular Biology

A single immunoglobulin-domain protein required for clustering acetylcholine receptors in C. elegans

Georgia Rapti et al.

EMBO JOURNAL (2011)

Article Neurosciences

Neto1 Is an Auxiliary Subunit of Native Synaptic Kainate Receptors

Man Tang et al.

JOURNAL OF NEUROSCIENCE (2011)

Article Genetics & Heredity

Genome-wide association study identifies five new schizophrenia loci

Stephan Ripke et al.

NATURE GENETICS (2011)

Article Multidisciplinary Sciences

The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins

Marc F. Bolliger et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Neurosciences

The Sushi Domains of GABAB Receptors Function as Axonal Targeting Signals

Barbara Biermann et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Multidisciplinary Sciences

Intron 4 Containing Novel GABAB1 Isoforms Impair GABAB Receptor Function

Changhoon Lee et al.

PLOS ONE (2010)

Article Multidisciplinary Sciences

A secreted complement-control-related protein ensures acetylcholine receptor clustering

Marie Gendrel et al.

NATURE (2009)

Article Multidisciplinary Sciences

Secreted semaphorins control spine distribution and morphogenesis in the postnatal CNS

Tracy S. Tran et al.

NATURE (2009)

Review Genetics & Heredity

OPINION The evolutionary significance of ancient genome duplications

Yves Van de Peer et al.

NATURE REVIEWS GENETICS (2009)

Review Neurosciences

The origin and evolution of synapses

Tomas J. Ryan et al.

NATURE REVIEWS NEUROSCIENCE (2009)

Review Neurosciences

Immune Proteins in Brain Development and Synaptic Plasticity

Lisa M. Boulanger

NEURON (2009)

Article Genetics & Heredity

A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia

Anna C. Need et al.

PLOS GENETICS (2009)

Article Biochemistry & Molecular Biology

The Sushi Domains of Secreted GABAB1 Isoforms Selectively Impair GABAB Heteroreceptor Function

Jim Y. Tiao et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Genetics & Heredity

Addiction molecular genetics: 639,401 SNP whole genome association identifies many cell adhesion genes

Qing-Rong Liu et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2006)

Article Biochemistry & Molecular Biology

Solution structures of the first and fourth TSR domains of F-spondin

Kimmo Paakkonen et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2006)

Article Multidisciplinary Sciences

Conserved SOL-1 proteins regulate ionotropic glutamate receptor desensitization

Craig S. Walker et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemical Research Methods

Protein family expansions and biological complexity

Christine Vogel et al.

PLOS COMPUTATIONAL BIOLOGY (2006)

Article Biochemistry & Molecular Biology

SRPX2 mutations in disorders of language cortex and cognition

P Roll et al.

HUMAN MOLECULAR GENETICS (2006)

Article Multidisciplinary Sciences

SOL-1 is an auxiliary subunit that modulates the gating of GLR-1 glutamate receptors in Caenorhabditis elegans

Y Zheng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis

KS Christopherson et al.

Article Biochemistry & Molecular Biology

Identification of novel β1 integrin binding sites in the type 1 and type 2 repeats of thrombospondin-1

MJ Calzada et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Developmental Biology

Expression of Btcl2, a novel member of Btcl gene family, during development of the central nervous system

M Michishita et al.

DEVELOPMENTAL BRAIN RESEARCH (2004)

Article Biochemistry & Molecular Biology

A novel gene, Btcl1, encoding CUB and LDLa domains is expressed in restricted areas of mouse brain

M Michishita et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)