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NATURE IMMUNOLOGY (2014)
Hypoxia Induces Autophagic Cell Death through Hypoxia-Inducible Factor 1α in Microglia
Zhao Yang et al.
PLOS ONE (2014)
Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy
Jiujiu Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation
Naeha Subramanian et al.
CELL (2013)
Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological deficits in stroke
Alessio Alfieri et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
NLRP3 Inflammasomes Show High Expression in Aorta of Patients with Atherosclerosis
Fei Zheng et al.
HEART LUNG AND CIRCULATION (2013)
Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation
Shankar S. Iyer et al.
IMMUNITY (2013)
The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity
Sangjun Park et al.
JOURNAL OF IMMUNOLOGY (2013)
P2X7R/cryopyrin inflammasome axis inhibition reduces neuroinflammation after SAH
Sheng Chen et al.
NEUROBIOLOGY OF DISEASE (2013)
Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke
D. Yang-Wei Fann et al.
CELL DEATH & DISEASE (2013)
Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
Kenichi Shimada et al.
IMMUNITY (2012)
Electroacupuncture pretreatment attenuates cerebral ischemic injury through α7 nicotinic acetylcholine receptor-mediated inhibition of high-mobility group box 1 release in rats
Qiang Wang et al.
JOURNAL OF NEUROINFLAMMATION (2012)
The NLRP3 inflammasome in health and disease: the good, the bad and the ugly
P. Menu et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2011)
Critical functions of priming and lysosomal damage for NLRP3 activation
Veit Hornung et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
Inflammatory mechanisms in ischemic stroke: role of inflammatory cells
Rong Jin et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2010)
NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?
Jurg Tschopp et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Post-ischemic brain damage: pathophysiology and role of inflammatory mediators
Diana Amantea et al.
FEBS JOURNAL (2009)
Alternative activation of macrophages: Immune function and cellular biology
Audrey Varin et al.
IMMUNOBIOLOGY (2009)
Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the NlrP3 Inflammasome
Sophie Joly et al.
JOURNAL OF IMMUNOLOGY (2009)
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
Veit Hornung et al.
NATURE IMMUNOLOGY (2008)
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
Uwe-Karsten Hanisch et al.
NATURE NEUROSCIENCE (2007)
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
V. Petrilli et al.
CELL DEATH AND DIFFERENTIATION (2007)
Pathophysiology and therapy of experimental stroke
Konstantin-Alexander Hossmann
CELLULAR AND MOLECULAR NEUROBIOLOGY (2006)
Cryopyrin activates the inflammasome in response to toxins and ATP
S Mariathasan et al.
NATURE (2006)
Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells
SL Fink et al.
INFECTION AND IMMUNITY (2005)
Exciting, radical, suicidal - How brain cells die after stroke
EH Lo et al.
STROKE (2005)
The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition
E Liepinsh et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
The inflammasome:: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
F Martinon et al.
MOLECULAR CELL (2002)
The PYRIN-CARD protein ASC is an activating adaptor for caspase-1
SM Srinivasula et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The danger model: A renewed sense of self
P Matzinger
SCIENCE (2002)