4.7 Article

Clinical, gut microbial and neural effects of a probiotic add-on therapy in depressed patients: a randomized controlled trial

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia

A. J. McGuinness et al.

Summary: The study investigated differences in gut microbiota composition between major psychiatric disorder patients and healthy individuals, finding disparities in overall community composition but no significant variation in the number or distribution of bacteria. Specific bacterial taxa associated with mental disorders were identified, suggesting potential commonalities in microbial signatures across different disorders. Further research using robust methodologies and guidelines is needed to enhance understanding of the role of gut microbiota in mental and brain health.

MOLECULAR PSYCHIATRY (2022)

Review Food Science & Technology

Short-chain fatty acids-producing probiotics: A novel source of psychobiotics

Yiwen Cheng et al.

Summary: Psychobiotics, live microorganisms with mental health benefits, are emerging as novel therapeutic options for psychiatric disorders. Studies have identified potential psychobiotic strains, particularly SCFAs-producing bacteria like Lactobacillus, Bifidobacterium, and Clostridium, which play specific roles in psychiatric disorders. These bacteria may modulate neurological processes via the microbiota-gut-brain axis, suggesting their potential as novel psychobiotics.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)

Article Neurosciences

Effect of synbiotic and probiotic supplementation on serum brain-derived neurotrophic factor level, depression and anxiety symptoms in hemodialysis patients: a randomized, double-blinded, clinical trial

Neda Haghighat et al.

Summary: In general, 12 weeks of synbiotic supplementation showed greater improvement in depression symptoms and serum BDNF levels compared to probiotic supplementation in HD patients, especially in the subgroup of patients with depression symptoms.

NUTRITIONAL NEUROSCIENCE (2021)

Review Medicine, General & Internal

Updated Review and Meta-Analysis of Probiotics for the Treatment of Clinical Depression: Adjunctive vs. Stand-Alone Treatment

Viktoriya L. Nikolova et al.

Summary: This review evaluated the efficacy of probiotics for clinical depression, showing that probiotics are effective in reducing depressive symptoms when used adjunctively with antidepressants, but not as a stand-alone treatment. Potential mechanisms of action may involve increases in BDNF and decreases in CRP levels, but more evidence is needed to support this.

JOURNAL OF CLINICAL MEDICINE (2021)

Article Microbiology

Lactobacillus strains derived from human gut ameliorate metabolic disorders via modulation of gut microbiota composition and short-chain fatty acids metabolism

G. Wang et al.

Summary: The study found that Lactobacillus strains partly protect against diet-induced metabolic syndrome by mediating the recovery of short-chain fatty acids production, especially faecal acetic acid. Probiotics restore gut microbiota dysbiosis to some extent, thereby protecting against metabolic disorders, without fully reversing the changed composition of microbiota to the normal state.

BENEFICIAL MICROBES (2021)

Review Microbiology

Short chain fatty acids in human gut and metabolic health

E. E. Blaak et al.

BENEFICIAL MICROBES (2020)

Meeting Abstract Clinical Neurology

Patients with major depressive disorder have lower cerebral serotonin 4 receptor binding than healthy controls

K. Koehler-Forsberg et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2020)

Article Microbiology

The neuroactive potential of the human gut microbiota in quality of life and depression

Mireia Valles-Colomer et al.

NATURE MICROBIOLOGY (2019)

Article Clinical Neurology

Gut feelings: A randomised, triple-blind, placebo-controlled trial of probiotics for depressive symptoms

Bahia Chahwan et al.

JOURNAL OF AFFECTIVE DISORDERS (2019)

Review Clinical Neurology

Cortical thickness in major depressive disorder: A systematic review and meta-analysis

Jee Su Suh et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2019)

Review Clinical Neurology

Effect of probiotic interventions on depressive symptoms: A narrative review evaluating systematic reviews

Ibrahim Nadeem et al.

PSYCHIATRY AND CLINICAL NEUROSCIENCES (2019)

Review Clinical Neurology

A meta-analysis of the use of probiotics to alleviate depressive symptoms

Qin Xiang Ng et al.

JOURNAL OF AFFECTIVE DISORDERS (2018)

Article Multidisciplinary Sciences

Quantitative microbiome profiling links gut community variation to microbial load

Doris Vandeputte et al.

NATURE (2017)

Article Biochemical Research Methods

DADA2: High-resolution sample inference from Illumina amplicon data

Benjamin J. Callahan et al.

NATURE METHODS (2016)

Article Multidisciplinary Sciences

Population-level analysis of gut microbiome variation

Gwen Falony et al.

SCIENCE (2016)

Article Biochemistry & Molecular Biology

Psychobiotics: An emerging probiotic in psychiatric practice

Arunava Kali

BIOMEDICAL JOURNAL (2016)

Article Immunology

Altered fecal microbiota composition in patients with major depressive disorder

Haiyin Jiang et al.

BRAIN BEHAVIOR AND IMMUNITY (2015)

Review Biochemical Research Methods

Gut brain axis: diet microbiota interactions and implications for modulation of anxiety and depression

Ruth Ann Luna et al.

CURRENT OPINION IN BIOTECHNOLOGY (2015)

Article Gastroenterology & Hepatology

Correlation between the human fecal microbiota and depression

A. Naseribafrouei et al.

NEUROGASTROENTEROLOGY AND MOTILITY (2014)

Review Neurosciences

Psychobiotics: A Novel Class of Psychotropic

Timothy G. Dinan et al.

BIOLOGICAL PSYCHIATRY (2013)

Article Gastroenterology & Hepatology

Lactobacillus acidophilus CRL 1014 improved gut health in the SHIME® reactor

Katia Sivieri et al.

BMC GASTROENTEROLOGY (2013)

Editorial Material Gastroenterology & Hepatology

Consumption of Fermented Milk Product With Probiotic Modulates Brain Activity

Kirsten Tillisch et al.

GASTROENTEROLOGY (2013)

Article Clinical Neurology

Severity classification on the Hamilton depression rating scale

Mark Zimmerman et al.

JOURNAL OF AFFECTIVE DISORDERS (2013)

Article Gastroenterology & Hepatology

Effect of probiotic bacteria on the intestinal microbiota in irritable bowel syndrome

Siew Chien Ng et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2013)

Review Behavioral Sciences

Emotional valence modulates brain functional abnormalities in depression: Evidence from a meta-analysis of fMRI studies

Nynke A. Groenewold et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2013)

Review Neurosciences

Gut-brain: how the microbiome influences anxiety and depression

Jane A. Foster et al.

TRENDS IN NEUROSCIENCES (2013)

Article Biotechnology & Applied Microbiology

γ-Aminobutyric acid production by culturable bacteria from the human intestine

E. Barrett et al.

JOURNAL OF APPLIED MICROBIOLOGY (2012)

Review Neurosciences

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

John F. Cryan et al.

NATURE REVIEWS NEUROSCIENCE (2012)

Review Neurosciences

Cognitive Mechanisms of Treatment in Depression

Jonathan P. Roiser et al.

NEUROPSYCHOPHARMACOLOGY (2012)

Review Medicine, General & Internal

Treatment-resistant depression: therapeutic trends, challenges, and future directions

Khalid Saad Al-Harbi

PATIENT PREFERENCE AND ADHERENCE (2012)

Article Multidisciplinary Sciences

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

Javier A. Bravo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Gastroenterology & Hepatology

Irritable Bowel Syndrome, Gut Microbiota and Probiotics

Beom Jae Lee et al.

JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY (2011)

Review Behavioral Sciences

Facial emotion processing in major depression: a systematic review of neuroimaging findings

Anja Stuhrmann et al.

BIOLOGY OF MOOD & ANXIETY DISORDERS (2011)

Article Agriculture, Dairy & Animal Science

Gastrointestinal tract morphological alteration by unpleasant physical treatment and modulating role of Lactobacillus in broilers

A. Meimandipour et al.

BRITISH POULTRY SCIENCE (2010)

Article Clinical Neurology

Meta-Analysis of Dropout Rates in SSRIs Versus Placebo in Randomized Clinical Trials of PTSD

Ido Lurie et al.

JOURNAL OF NERVOUS AND MENTAL DISEASE (2010)

Article Psychiatry

Response and remission criteria in major depression - A validation of current practice

Michael Riedel et al.

JOURNAL OF PSYCHIATRIC RESEARCH (2010)

Article Neurosciences

Neurocognitive Mechanisms in Depression: Implications for Treatment

Luke Clark et al.

Annual Review of Neuroscience (2009)

Article Psychology, Mathematical

G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences

Franz Faul et al.

BEHAVIOR RESEARCH METHODS (2007)

Article Medicine, General & Internal

Remission, dropouts, and adverse drug reaction rates in major depressive disorder: a meta-analysis of head-to-head trials

Marcio Machado et al.

CURRENT MEDICAL RESEARCH AND OPINION (2006)

Article Psychiatry

Depression biases the recognition of emotionally neutral faces

JM Leppänen et al.

PSYCHIATRY RESEARCH (2004)

Article Clinical Neurology

Risk factors and predictors of compliance in depression

K Demyttenaere

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2003)

Article Psychiatry

When should a trial of fluoxetine for major depression be declared failed?

FM Quitkin et al.

AMERICAN JOURNAL OF PSYCHIATRY (2003)