4.2 Article

Gastrointestinal Dysfunction Impact on Life Quality in a Cohort of Russian Patients with Parkinson's Disease I-III H&Y Stage

Related references

Note: Only part of the references are listed.
Article Clinical Neurology

Correlation between depression and quality of life in patients with Parkinson's disease

Wen Su et al.

Summary: This study found that PD patients with depression had significantly higher scores in all domains of PDQ-39 compared to those without depression. Patients in the depression group had longer disease duration, higher UPDRS-III scores, and higher H-Y stage levels. Various factors including age, disease duration, UPDRS-III, H-Y stage, HAMD score may independently affect PDQ-39SI in PD patients, with HAMD having the greatest impact.

CLINICAL NEUROLOGY AND NEUROSURGERY (2021)

Review Medicine, General & Internal

Sexual Disorders and Quality of Life in Parkinson's Disease

Claudia Marques Santa Rosa Malcher et al.

Summary: Sexual disorders are common in patients with Parkinson's disease, especially in men, which can significantly impair their quality of life. Early recognition and treatment of these issues are crucial to prevent serious consequences for patients.

SEXUAL MEDICINE (2021)

Review Medicine, General & Internal

Gastrointestinal Dysfunction in Parkinson's Disease

Casper Skjaerbaek et al.

Summary: Parkinson's disease is the second most common neurodegenerative disease characterized by pathological alpha-synuclein deposits in both the brain and the entire digestive tract. Gastrointestinal symptoms such as dysphagia, bloating, and constipation are common in PD patients. The accumulation of gastrointestinal pathology may begin years before a clinical diagnosis of PD, with constipation shown to increase the risk of PD and truncal vagotomy potentially decreasing the risk.

JOURNAL OF CLINICAL MEDICINE (2021)

Article Clinical Neurology

Characterization of Gastrointestinal Symptom Type and Severity in Parkinson's Disease: A Case-Control Study in an Australian Cohort

Jade E. Kenna et al.

Summary: This study investigated the spectrum of gastrointestinal symptoms in an Australian cohort of Parkinson's disease patients, finding that they reported a higher frequency of constipation and GI-associated illnesses compared to healthy controls. The use of anti-Parkinsonian medications was positively associated with the severity of GI symptoms.

MOVEMENT DISORDERS CLINICAL PRACTICE (2021)

Article Clinical Neurology

Health-Related Quality of Life for Parkinson's Disease Patients and Their Caregivers

Michal Lubomski et al.

Summary: The study found that Parkinson's disease patients reported significantly decreased health-related quality of life (HRQoL), with factors such as unemployment, the need for social support services, REM sleep behavior disorder, impulse control disorders, and features suggestive of increasing disease severity contributing to lower HRQoL. Additionally, decreased physical activity, chronic pain, depression, constipation, and upper gastrointestinal dysfunction were associated with reduced HRQoL in PD patients.

JOURNAL OF MOVEMENT DISORDERS (2021)

Article Clinical Neurology

Does Depression Contribute to the Bladder and Bowel Complaint in Parkinson's Disease Patients?

Ryuji Sakakibara et al.

Summary: This study found that Parkinson's disease patients with depression were more likely to experience constipation and sensation of residual urine, suggesting that depression may exacerbate bladder and bowel symptoms in PD patients.

MOVEMENT DISORDERS CLINICAL PRACTICE (2021)

Article Clinical Neurology

Depression Is Associated With Constipation in Patients With Parkinson's Disease

Qin Xiao-ling et al.

FRONTIERS IN NEUROLOGY (2020)

Review Clinical Neurology

Treatment of Autonomic Dysfunction in Parkinson Disease and Other Synucleinopathies

Jose-Alberto Palma et al.

MOVEMENT DISORDERS (2018)

Review Clinical Neurology

Gastrointestinal Dysfunctions in Parkinson's Disease: Symptoms and Treatments

Andree-Anne Poirier et al.

PARKINSONS DISEASE (2016)

Article Multidisciplinary Sciences

Heterogeneous Determinants of Quality of Life in Different Phenotypes of Parkinson's Disease

Seyed-Mohammad Fereshtehnejad et al.

PLOS ONE (2015)

Article Neurosciences

Meta-analyses on prevalence of selected Parkinson's nonmotor symptoms before and after diagnosis

Honglei Chen et al.

TRANSLATIONAL NEURODEGENERATION (2015)

Article Clinical Neurology

Determinants of the quality of life in Parkinson's disease: Results of a cohort study from Southwest China

Ying Wu et al.

JOURNAL OF THE NEUROLOGICAL SCIENCES (2014)

Article Clinical Neurology

Health-related quality of life in early Parkinson's disease: The impact of nonmotor symptoms

Gordon W. Duncan et al.

MOVEMENT DISORDERS (2014)

Review Clinical Neurology

Gastrointestinal Features of Parkinson's Disease

Leslie J. Cloud et al.

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2011)

Article Clinical Neurology

The Impact of Non-Motor Symptoms on Health-Related Quality of Life of Patients with Parkinson's Disease

Pablo Martinez-Martin et al.

MOVEMENT DISORDERS (2011)

Review Clinical Neurology

Determinants of health-related quality of life in Parkinson's disease: A systematic review

Sze-Ee Soh et al.

PARKINSONISM & RELATED DISORDERS (2011)

Article Clinical Neurology

A comprehensive model of health-related quality of life in Parkinson's disease

M. Visser et al.

JOURNAL OF NEUROLOGY (2008)

Article Clinical Neurology

The 39 item Parkinson's disease questionnaire (PDQ-39) revisited: implications for evidence based medicine

Peter Hagell et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2007)