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PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2006)
Caenorhabditis elegans ivermectin receptors regulate locomotor behaviour and are functional orthologues of Haemonchus contortus receptors
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MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2006)
QPatch: the past, present and future of automated patch clamp
C Mathes
EXPERT OPINION ON THERAPEUTIC TARGETS (2006)
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NATURE (2006)
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NATURE (2006)
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A high-capacity membrane potential FRET-based assay for Nav1.8 channels
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ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2006)
RNA interference in Haemonchus contortus: Suppression of beta-tubulin gene expression in L3, L4 and adult worms in vitro
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MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2006)
Identification of molluscan nicotinic acetylcholine receptor (nAChR) subunits involved in formation of cation- and anion-selective nAChRs
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JOURNAL OF NEUROSCIENCE (2005)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The Ror receptor tyrosine kinase CAM-1 is required for ACR-16-mediated synaptic transmission at the C. elegans neuromuscular junction
MM Francis et al.
NEURON (2005)
Differential regulation of TRPM channels governs electrolyte homeostasis in the C. elegans intestine
T Teramoto et al.
CELL METABOLISM (2005)
The Caenorhabditis elegans lev-8 gene encodes a novel type of nicotinic acetylcholine receptor α subunit
PR Towers et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Chemistry-to-gene screens in Caenorhabditis elegans
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NATURE REVIEWS DRUG DISCOVERY (2005)
TILLING without a plough: a new method with applications for reverse genetics
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CURRENT OPINION IN PLANT BIOLOGY (2005)
Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution
N Unwin
JOURNAL OF MOLECULAR BIOLOGY (2005)
RNAi-based discovery and validation of new drug targets in filarial nematodes
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TRENDS IN PARASITOLOGY (2005)
A family of acetylcholine-gated chloride channel subunits in Caenorhabditis elegans
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Expression profiling of GABAergic motor neurons in Caenorhabditis elegans
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CURRENT BIOLOGY (2005)
The composition of the GABA receptor at the Caenorhabditis elegans neuromuscular junction
BA Bamber et al.
BRITISH JOURNAL OF PHARMACOLOGY (2005)
A transmembrane protein required for acetylcholine receptor clustering in Caenorhabditis elegans
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NATURE (2004)
Latrotoxin receptor signaling engages the UNC-13-dependent vesicle-priming pathway in C. elegans
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CURRENT BIOLOGY (2004)
An ivermectin-sensitive glutamate-gated chloride channel subunit from Dirofilaria immitis
DM Yates et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY (2004)
A transcriptomic analysis of the phylum Nematoda
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NATURE GENETICS (2004)
Genetic variability of glutamate-gated chloride channel genes in ivermectin-susceptible and -resistant strains of Cooperia oncophora
AI Njue et al.
PARASITOLOGY (2004)
eat-2 and eat-18 are required for nicotinic neurotransmission in the Caenorhabditis elegans pharynx
JP McKay et al.
GENETICS (2004)
Genomic cis-regulatory architecture and trans-acting regulators of a single interneuron-specific gene battery in C-elegans
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DEVELOPMENTAL CELL (2004)
Mutations in the extracellular domains of glutamate-gated chloride channel α3 and β subunits from ivermectin-resistant Cooperia oncophora affect agonist sensitivity
AI Njue et al.
JOURNAL OF NEUROCHEMISTRY (2004)
TILLING. Traditional mutagenesis meets functional genomics
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PLANT PHYSIOLOGY (2004)
The Caenorhabditis elegans unc-63 gene encodes a Levamisole-sensitive nicotinic acetylcholine receptor α subunit
E Culetto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Automated tight seal electrophysiology for assessing the potential hERG liability of pharmaceutical compounds
HM Tao et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2004)
Functional genomics of the nicotinic acetylcholine receptor gene family of the nematode, Caenorhabditis elegans
AK Jones et al.
BIOESSAYS (2004)
The use of Caenorhabditis elegans in parasitic nematode research
JS Gilleard
PARASITOLOGY (2004)
Trends in ion channel drug discovery: advances in screening technologies
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TRENDS IN BIOTECHNOLOGY (2003)
EXP-1 is an excitatory GABA-gated cation channel
AA Beg et al.
NATURE NEUROSCIENCE (2003)
A benchmark study with SealChip™ planar patch-clamp technology
J Xu et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2003)
Comparative study of membrane potential-sensitive fluorescent probes and their use in ion channel screening assays
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JOURNAL OF BIOMOLECULAR SCREENING (2003)
Flux assays in high throughput screening of ion channels in drug discovery
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ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2003)
The avermectin receptors of Haemonchus contortus and Caenorhabditis elegans
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INTERNATIONAL JOURNAL FOR PARASITOLOGY (2003)
Distribution of glutamate-gated chloride channel subunits in the parasitic nematode Haemonchus contortus
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JOURNAL OF COMPARATIVE NEUROLOGY (2003)
Functional properties of homomeric, human α7-nicotinic acetylcholine receptors heterologously expressed in the SH-EP1 human epithelial cell line
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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Haemonchus contortus:: HcGluCla expressed in Xenopus oocytes forms a glutamate-gated ion channel that is activated by ibotenate and the antiparasitic drug ivermectin
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MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2003)
From genes to integrative physiology:: Ion channel and transporter biology in Caenorhabditis elegans
K Strange
PHYSIOLOGICAL REVIEWS (2003)
Pharmacological characterization of the homomeric and heteromeric UNC-49 GABA receptors in C-elegans
BA Bamber et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
IonWorks™ HT:: A new high-throughput electrophysiology measurement platform
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JOURNAL OF BIOMOLECULAR SCREENING (2003)
Bridging the gap between genes and behavior:: recent advances in the electrophysiological analysis of neural function in Caenorhabditis elegans
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TRENDS IN NEUROSCIENCES (2003)
Gene expression profiling of cells, tissues, and developmental stages of the nematode C-elegans
SJ McKay et al.
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY (2003)
Mass drug treatment for lymphatic filariasis and onchocerciasis
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TRENDS IN PARASITOLOGY (2003)
The diversity of subunit composition in nAChRs:: Evolutionary origins, physiologic and pharmacologic consequences
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JOURNAL OF NEUROBIOLOGY (2002)
Study of the nematode putative GABA type-A receptor subunits: evidence for modulation by ivermectin
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JOURNAL OF NEUROCHEMISTRY (2002)
The L-type voltage-dependent Ca2+ channel EGL-19 controls body wall muscle,function in Caenorhabditis elegans
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Paraherquamide and 2-deoxy-paraherquamide distinguish cholinergic receptor subtypes in Ascaris muscle
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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Novel animal-health drug targets from ligand-gated chloride channels
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NATURE REVIEWS DRUG DISCOVERY (2002)
TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization
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CELL (2002)
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PROTEIN SCIENCE (2002)
The art and design of genetic screens:: Caenorhabditis elegans
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NATURE REVIEWS GENETICS (2002)
A glutamate-gated chloride channel subunit from Haemonchus contortus:: Expression in a mammalian cell line, ligand binding, and modulation of anthelmintic binding by glutamate
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BIOCHEMICAL PHARMACOLOGY (2002)
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NATURE REVIEWS NEUROSCIENCE (2002)
The C-elegans ric-3 gene is required for maturation of nicotinic acetylcholine receptors
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EMBO JOURNAL (2002)
Filaricidal efficacy of anthelmintically active cyclodepsipeptides
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INTERNATIONAL JOURNAL FOR PARASITOLOGY (2001)
Characterization of glutamate-gated chloride channels in the pharynx of wild-type and mutant Caenorhabditis elegans delineates the role of the subunit GluCl-α2 in the function of the native receptor
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MOLECULAR PHARMACOLOGY (2001)
High-affinity ivermectin binding to recombinant subunits of the Haemonchus contortus glutamate-gated chloride channel
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MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2001)
Characterization of the DEG-3/DES-2 receptor: A nicotinic acetylcholine receptor that mutates to cause neuronal degeneration
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MOLECULAR AND CELLULAR NEUROSCIENCE (2001)
GLC-3:: a novel fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit from Caenorhabditis elegans
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Pyrantel resistance alters nematode nicotinic acetylcholine receptor single-channel properties
AP Robertson et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2000)
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NATURE BIOTECHNOLOGY (2000)
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
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NATURE GENETICS (2000)
Anthelmintic actions on homomer-forming nicotinic acetylcholine receptor subunits: chicken alpha 7 and ACR-16 from the nematode Caenorhabditis elegans
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NEUROSCIENCE (2000)
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