Related references
Note: Only part of the references are listed.Clostridioides difficile toxins: mechanisms of action and antitoxin therapeutics
Shannon L. Kordus et al.
NATURE REVIEWS MICROBIOLOGY (2022)
Large Clostridial Toxins: Mechanisms and Roles in Disease
Kathleen E. Orrell et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2021)
Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease
Steven J. Mileto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Clostridioides difficile Toxin A-Induced Wnt/β-Catenin Pathway Inhibition Is Mediated by Rac1 Glucosylation
Conceicao S. Martins et al.
FRONTIERS IN MICROBIOLOGY (2020)
The Antibiotic Bacitracin Protects Human Intestinal Epithelial Cells and Stem Cell-Derived Intestinal Organoids from Clostridium difficile Toxin TcdB
Ziyu Zhu et al.
STEM CELLS INTERNATIONAL (2019)
Expression and (Lacking) Internalization of the Cell Surface Receptors of Clostridioides difficile Toxin B
Dennis Schoettelndreier et al.
FRONTIERS IN MICROBIOLOGY (2018)
Difference in Mono-O-Glucosylation of Ras Subtype GTPases Between Toxin A and Toxin B From Clostridioides difficile Strain 10463 and Lethal Toxin From Clostridium sordellii Strain 6018
Harald Genth et al.
FRONTIERS IN MICROBIOLOGY (2018)
Enteric glial cells are susceptible to Clostridium difficile toxin B
Katia Fettucciari et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
Glucosyltransferase Activity of Clostridium difficile Toxin B Triggers Autophagy-mediated Cell Growth Arrest
Ruina He et al.
SCIENTIFIC REPORTS (2017)
DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP
Maximilian Mimmler et al.
NUCLEIC ACIDS RESEARCH (2016)
Metal Ion Activation of Clostridium sordellii Lethal Toxin and Clostridium difficile Toxin B
Harald Genth et al.
TOXINS (2016)
Clostridium difficile infection
Wiep Klaas Smits et al.
NATURE REVIEWS DISEASE PRIMERS (2016)
The intestinal epithelial cell cycle: uncovering its 'cryptic' nature
Declan P. McKernan et al.
CURRENT OPINION IN GASTROENTEROLOGY (2015)
Meta-analysis of the relationship between XRCC3 T241M polymorphism and colorectal cancer susceptibility
L. Z. Zhang et al.
GENETICS AND MOLECULAR RESEARCH (2015)
Rac1-dependent recruitment of PAK2 to G2 phase centrosomes and their roles in the regulation of mitotic entry
Martin May et al.
CELL CYCLE (2014)
Pyknotic cell death induced by Clostridium difficile TcdB: chromatin condensation and nuclear blister are induced independently of the glucosyltransferase activity
Katharina Wohlan et al.
CELLULAR MICROBIOLOGY (2014)
Haemorrhagic toxin and lethal toxin from Clostridium sordellii strain vpi9048: molecular characterization and comparative analysis of substrate specificity of the large clostridial glucosylating toxins
Harald Genth et al.
CELLULAR MICROBIOLOGY (2014)
Molecular Pathways: Targeting RAC-p21-Activated Serine-Threonine Kinase Signaling in RAS-Driven Cancers
Nicole M. Baker et al.
CLINICAL CANCER RESEARCH (2014)
The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength
Wim de Lau et al.
GENES & DEVELOPMENT (2014)
Canonical Wnt signals combined with suppressed TGFβ/BMP pathways promote renewal of the native human colonic epithelium
Amy Reynolds et al.
GUT (2014)
Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration
Nick Barker
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
PAK signalling during the development and progression of cancer
Maria Radu et al.
NATURE REVIEWS CANCER (2014)
ROS Production and NF-κB Activation Triggered by RAC1 Facilitate WNT-Driven Intestinal Stem Cell Proliferation and Colorectal Cancer Initiation
Kevin B. Myant et al.
CELL STEM CELL (2013)
Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation
Anika Steffen et al.
JOURNAL OF CELL SCIENCE (2013)
Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex
Melissa A. Farrow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Difference in F-Actin Depolymerization Induced by Toxin B from the Clostridium difficile Strain VPI 10463 and Toxin B from the Variant Clostridium difficile Serotype F Strain 1470
Martin May et al.
TOXINS (2013)
Protection from Clostridium difficile toxin B-catalysed Rac1/Cdc42 glucosylation by tauroursodeoxycholic acid-induced Rac1/Cdc42 phosphorylation
Vanessa Brandes et al.
BIOLOGICAL CHEMISTRY (2012)
Systems analysis of the transcriptional response of human ileocecal epithelial cells to Clostridium difficile toxins and effects on cell cycle control
Kevin M. D'Auria et al.
BMC SYSTEMS BIOLOGY (2012)
Cyclin D3 Compensates for the Loss of Cyclin D1 during ErbB2-Induced Mammary Tumor Initiation and Progression
Qian Zhang et al.
CANCER RESEARCH (2011)
Difference in the biological effects of Clostridium difficile toxin B in proliferating and non-proliferating cells
Marta Lica et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2011)
Rac and Rho GTPases in cancer cell motility control
Matteo Parri et al.
CELL COMMUNICATION AND SIGNALING (2010)
Immortalized Epithelial Cells Derived From Human Colon Biopsies Express Stem Cell Markers and Differentiate In Vitro
Andres I. Roig et al.
GASTROENTEROLOGY (2010)
Differential roles of cyclin D1 and D3 in pancreatic ductal adenocarcinoma
Nikolina Radulovich et al.
MOLECULAR CANCER (2010)
Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1
Etienne Boulter et al.
NATURE CELL BIOLOGY (2010)
Inhibition of Cytokinesis by Clostridium difficile Toxin B and Cytotoxic Necrotizing Factors-Reinforcing the Critical Role of RhoA in Cytokinesis
Stefanie C. Huelsenbeck et al.
CELL MOTILITY AND THE CYTOSKELETON (2009)
Inactivation of Rho GTPases with Clostridium difficile toxin B impairs centrosomal activation of Aurora-A in G2/M transition of HeLa cells
Yoshikazu Ando et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Clostridium difficile toxin A-induced apoptosis is p53-independent but depends on glucosylation of Rho GTPases
Stefanie Nottrott et al.
APOPTOSIS (2007)
NFκB-independent signaling to the cyclin D1 gene by Rac
Eric A. Klein et al.
CELL CYCLE (2007)
Upregulation of the immediate early gene product RhoB by exoenzyme C3 from Clostridium limosum and toxin B from Clostridium difficile
Johannes Huelsenbeck et al.
BIOCHEMISTRY (2007)
Clostridium difficile toxin B causes apoptosis in epithelial cells by thrilling mitochondria -: Involvement of ATP-sensitive mitochondrial potassium channels
Paola Matarrese et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity
M. Thullberg et al.
ONCOGENE (2007)
Cellular stability of Rho-GTPases glucosylated by Clostridium difficile toxin B
Harald Genth et al.
FEBS LETTERS (2006)
The Rho GTPase effector ROCK regulates cyclin A, cyclin D1, and p27Kip1 levels by distinct mechanisms
Daniel R. Croft et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells
A Czuchra et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells
S Balasenthil et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Expression of recombinant Clostridium difficile toxin A using the Bacillus megaterium system
S Burger et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Share Paper
