☆ 4.6 Review

Inflammatory Bowel Disease and COVID-19: How Microbiomics and Metabolomics Depict Two Sides of the Same Coin

FRONTIERS IN MICROBIOLOGY (2022)

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GUT (2020)

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Letter Gastroenterology & Hepatology

A fatal case of COVID-19 pneumonia occurring in a patient with severe acute ulcerative colitis

Stefano Mazza et al.

GUT (2020)

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Crohn's Disease Differentially Affects Region-Specific Composition and Aerotolerance Profiles of Mucosally Adherent Bacteria

Nur M. Shahir et al.

INFLAMMATORY BOWEL DISEASES (2020)

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Review Biochemistry & Molecular Biology

Adherent-Invasive E. coli: Update on the Lifestyle of a Troublemaker in Crohn's Disease

Melissa Chervy et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Article Medicine, General & Internal

Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy

Giacomo Grasselli et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

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Are Patients with Inflammatory Bowel Disease at Increased Risk for Covid-19 Infection?

Giovanni Monteleone et al.

JOURNAL OF CROHNS & COLITIS (2020)

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SARS-CoV-2 productively infects human gut enterocytes

Mart M. Lamers et al.

SCIENCE (2020)

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Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease

F. J. Ryan et al.

NATURE COMMUNICATIONS (2020)

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Histidine in Health and Disease: Metabolism, Physiological Importance, and Use as a Supplement

Milan Holecek

NUTRIENTS (2020)

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Review Nutrition & Dietetics

Histidine: A Systematic Review on Metabolism and Physiological Effects in Human and Different Animal Species

Joanna Moro et al.

NUTRIENTS (2020)

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Plasma metabolomic and lipidomic alterations associated with COVID-19

Di Wu et al.

NATIONAL SCIENCE REVIEW (2020)

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Systematic Review on Inflammatory Bowel Disease Patients With Coronavirus Disease 2019: It Is Time to Take Stock

Ferdinando D'Amico et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2020)

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Alterations of the Gut Microbiota in Patients With Coronavirus Disease 2019 or H1N1 Influenza

Silan Gu et al.

CLINICAL INFECTIOUS DISEASES (2020)

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What about COVID-19 and arachidonic acid pathway?

Malvina Hoxha

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2020)

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Abnormal concentration of porphyrins in serum from COVID-19 patients

Itxaso San Juan et al.

BRITISH JOURNAL OF HAEMATOLOGY (2020)

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Omics-Driven Systems Interrogation of Metabolic Dysregulation in COVID-19 Pathogenesis

Jin-Wen Song et al.

CELL METABOLISM (2020)

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The Incidence and Outcomes of COVID-19 in IBD Patients: A Rapid Review and Meta-analysis

Muhammad Aziz et al.

INFLAMMATORY BOWEL DISEASES (2020)

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Clinical Significance of the Correlation between Changes in the Major Intestinal Bacteria Species and COVID-19 Severity

Lingling Tang et al.

ENGINEERING (2020)

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COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status

Tiffany Thomas et al.

JCI INSIGHT (2020)

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Eicosanoids

Philip C. Calder

LIPID MEDIATORS (2020)

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Glutamine reliance in cell metabolism

Hee Chan Yoo et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2020)

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Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Patients With In fl ammatory Bowel Disease Under Biologic Treatment

Lorenzo Norsa et al.

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Endogenous Indole Pyruvate Pathway for Tryptophan Metabolism Mediated by IL4I1

Xia Zhang et al.

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Article Biochemical Research Methods

Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection

Torben Kimhofer et al.

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COVID-19: Proposing a Ketone-Based Metabolic Therapy as a Treatment to Blunt the Cytokine Storm

Patrick C. Bradshaw et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)

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An immune therapy model for effective treatment on inflammatory bowel disease

Anna Park et al.

PLOS ONE (2020)

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Review of inflammatory bowel disease and COVID-19

Keith Sultan et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2020)

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Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity

Wenjing Yang et al.

NATURE COMMUNICATIONS (2020)

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The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolism

H. Blasco et al.

SCIENTIFIC REPORTS (2020)

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Updating Phospholipase A(2) Biology

Makoto Murakami et al.

BIOMOLECULES (2020)

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Incidence and Persistence of Viral Shedding in COVID-19 Post-acute Patients With Negativized Pharyngeal Swab: A Systematic Review

Giovanni Morone et al.

FRONTIERS IN MEDICINE (2020)

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SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of Serum

Chiara Bruzzone et al.

ISCIENCE (2020)

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Large-Scale Plasma Analysis Revealed New Mechanisms and Molecules Associated with the Host Response to SARS-CoV-2

Elettra Barberis et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Gastrointestinal symptoms associated with COVID-19: impact on the gut microbiome

Sonia Villapol

TRANSLATIONAL RESEARCH (2020)

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Investigating Ketone Bodies as Immunometabolic Countermeasures against Respiratory Viral Infections

Brianna J. Stubbs et al.

MED (2020)

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Patients with Inflammatory Bowel Disease Are Not at Increased Risk of COVID-19: A Large Multinational Cohort Study

Mariangela Allocca et al.

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Computational modelling provides insight into the effects of glyphosate on the shikimate pathway in the human gut microbiome

Robin Mesnage et al.

CURRENT RESEARCH IN TOXICOLOGY (2020)

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Effect of COVID-19 on the Organs

Uday Jain

CUREUS JOURNAL OF MEDICAL SCIENCE (2020)

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The Incidence and Outcomes of COVID-19 in IBD Patients: A Rapid Review and Meta-analysis

Muhammad Aziz et al.

INFLAMMATORY BOWEL DISEASES (2020)

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Eicosanoids in the gastrointestinal tract

John L. Wallace

BRITISH JOURNAL OF PHARMACOLOGY (2019)

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Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma-Application to Clinical and Epidemiology Cohorts

Luke Whiley et al.

ANALYTICAL CHEMISTRY (2019)

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Article Biochemistry & Molecular Biology

Serum Metabolomics Identifies Altered Bioenergetics, Signaling Cascades in Parallel with Exposome Markers in Crohn's Disease

Yunjia Lai et al.

MOLECULES (2019)

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Interleukin-22 protects intestinal stem cells against genotoxic stress

Konrad Gronke et al.

NATURE (2019)

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Altered fecal bacterial composition correlates with disease activity in inflammatory bowel disease and the extent of IL8 induction

Farnaz Heidarian et al.

CURRENT RESEARCH IN TRANSLATIONAL MEDICINE (2019)

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Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

Jason Lloyd-Price et al.

NATURE (2019)

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The prevalence of mucosa-associated diffusely adherent Escherichia coli in children with inflammatory bowel disease

Urszula Walczuk et al.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE (2019)

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Lipidomic signatures of colonic inflammatory bowel diseases: a pilot study

Cristian Tefas et al.

JOURNAL OF GASTROINTESTINAL AND LIVER DISEASES (2019)

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Review Immunology

Targeting immune cell circuits and trafficking in inflammatory bowel disease

Markus F. Neurath

NATURE IMMUNOLOGY (2019)

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Akkermansia muciniphila induces intestinal adaptive immune responses during homeostasis

Eduard Ansaldo et al.

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Fecal and Mucosal Microbiota Profiling in Irritable Bowel Syndrome and Inflammatory Bowel Disease

Alessandra Lo Presti et al.

FRONTIERS IN MICROBIOLOGY (2019)

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Ketone Bodies in Neurological Diseases: Focus on Neuroprotection and Underlying Mechanisms

Huajun Yang et al.

FRONTIERS IN NEUROLOGY (2019)

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Article Biochemistry & Molecular Biology

Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans

Thomas Hagan et al.

CELL (2019)

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The Relationship Between the Serotonin Metabolism, Gut-microbiota and the Gut-brain Axis

Cristina Stasi et al.

CURRENT DRUG METABOLISM (2019)

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Inflammatory Bowel Disease Presentation and Diagnosis

Sean Flynn et al.

SURGICAL CLINICS OF NORTH AMERICA (2019)

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Akkermansia muciniphila-Derived Extracellular Vesicles as a Mucosal Delivery Vector for Amelioration of Obesity in Mice

Fatemeh Ashrafian et al.

FRONTIERS IN MICROBIOLOGY (2019)

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Comorbidities in inflammatory bowel disease: a call for action

Marjorie Argollo et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2019)

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Alteration of Gut Microbiota in Inflammatory Bowel Disease (IBD): Cause or Consequence? IBD Treatment Targeting the Gut Microbiome

Israr Khan et al.

PATHOGENS (2019)

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The Role of Glutamine in the Complex Interaction between Gut Microbiota and Health: A Narrative Review

Simone Perna et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

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Review Immunology

The gut microbiome: Relationships with disease and opportunities for therapy

Juliana Durack et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2019)

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Integrated serum proteins and fatty acids analysis for putative biomarker discovery in inflammatory bowel disease

Marcello Manfredi et al.

JOURNAL OF PROTEOMICS (2019)

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Succinate receptor mediates intestinal inflammation and fibrosis

Dulce C. Macias-Ceja et al.

MUCOSAL IMMUNOLOGY (2019)

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Microbial network disturbances in relapsing refractory Crohn's disease

Bahtiyar Yilmaz et al.

NATURE MEDICINE (2019)

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An evolutionary perspective on immunometabolism

Andrew Wang et al.

SCIENCE (2019)

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Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication

Bingpeng Yan et al.

VIRUSES-BASEL (2019)

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The Role of Dietary Nutrients in Inflammatory Bowel Disease

Kohei Sugihara et al.

FRONTIERS IN IMMUNOLOGY (2019)

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Gut microbiome structure and metabolic activity in inflammatory bowel disease

Eric A. Franzosa et al.

NATURE MICROBIOLOGY (2019)

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Adherent-invasive Escherichia coli in inflammatory bowel disease

Carolina Palmela et al.

GUT (2018)

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Determinants of Reduced Genetic Capacity for Butyrate Synthesis by the Gut Microbiome in Crohn's Disease and Ulcerative Colitis

Emilio J. Laserna-Mendieta et al.

JOURNAL OF CROHNS & COLITIS (2018)

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Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease

Kyohei Nishino et al.

JOURNAL OF GASTROENTEROLOGY (2018)

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Inhibition of Cytosolic Phospholipase A2α Impairs an Early Step of Coronavirus Replication in Cell Culture

Christin Mueller et al.

JOURNAL OF VIROLOGY (2018)

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Alterations in lipid, amino acid, and energy metabolism distinguish Crohn's disease from ulcerative colitis and control subjects by serum metabolomic profiling

Elizabeth A. Scoville et al.

METABOLOMICS (2018)

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Review Microbiology

Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease

Allison Agus et al.

CELL HOST & MICROBE (2018)

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Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative Colitis

Fay Probert et al.

JOURNAL OF CROHNS & COLITIS (2018)

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Article Gastroenterology & Hepatology

Fecal Amino Acid Analysis Can Discriminate De Novo Treatment-Naive Pediatric Inflammatory Bowel Disease From Controls

Sofie Bosch et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2018)

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Indoleamine 2, 3-dioxygenase regulation of immune response

Hao Wu et al.

MOLECULAR MEDICINE REPORTS (2018)

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Aryl hydrocarbon receptor and intestinal immunity

Bruno Lamas et al.

MUCOSAL IMMUNOLOGY (2018)

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Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism

Jing Gao et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2018)

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Arachidonic acid: Physiological roles and potential health benefits - A review

Hatem Tallima et al.

JOURNAL OF ADVANCED RESEARCH (2018)

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Variability of core microbiota in newly diagnosed treatment-naive paediatric inflammatory bowel disease patients

T. G. J. de Meij et al.

PLOS ONE (2018)

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Microbial tryptophan catabolites in health and disease

Henrik M. Roager et al.

NATURE COMMUNICATIONS (2018)

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The Gut Microbiota in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease

Tao Zuo et al.

FRONTIERS IN MICROBIOLOGY (2018)

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Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation

Vinicius Cruzat et al.

NUTRIENTS (2018)

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Fungal microbiota dysbiosis in IBD

Harry Sokol et al.

GUT (2017)

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Faecal and Serum Metabolomics in Paediatric Inflammatory Bowel Disease

Kaija-Leena Kolho et al.

JOURNAL OF CROHNS & COLITIS (2017)

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Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases

Susanna Nikolaus et al.

GASTROENTEROLOGY (2017)

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A microbial signature for Crohn's disease

Victoria Pascal et al.

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Risk for Overall Infection with Anti-TNF and Anti-integrin Agents Used in IBD: A Systematic Review and Meta-analysis

Eric D. Shah et al.

INFLAMMATORY BOWEL DISEASES (2017)

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The Roles of Glutamine in the Intestine and Its Implication in Intestinal Diseases

Min-Hyun Kim et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

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Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies

Siew C. Ng et al.

LANCET (2017)

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PXR: More Than Just a Master Xenobiotic Receptor

Peter O. Oladimeji et al.

MOLECULAR PHARMACOLOGY (2017)

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A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

Dylan Dodd et al.

NATURE (2017)

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Tryptophan availability for kynurenine pathway metabolism across the life span: Control mechanisms and focus on aging, exercise, diet and nutritional supplements

Abdulla A-B. Badawy

NEUROPHARMACOLOGY (2017)

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Metabolomics: A Primer

Xiaojing Liu et al.

TRENDS IN BIOCHEMICAL SCIENCES (2017)

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Partners of patients with ulcerative colitis exhibit a biologically relevant dysbiosis in fecal microbial metacommunities

Guang-Lan Chen et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2017)

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Dietary and metabolomic determinants of relapse in ulcerative colitis patients: A pilot prospective cohort study

Ammar Hassanzadeh Keshteli et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2017)

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Dynamics of the human gut microbiome in inflammatory bowel disease

Jonas Halfvarson et al.

NATURE MICROBIOLOGY (2017)

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Intestinal Bacteria Composition and Translocation of Bacteria in Inflammatory Bowel Disease

Spyros Vrakas et al.

PLOS ONE (2017)

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Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function

Noora Ottman et al.

PLOS ONE (2017)

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Cross sectional evaluation of the gut-microbiome metabolome axis in an Italian cohort of IBD patients

Maria Laura Santoru et al.

SCIENTIFIC REPORTS (2017)

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Metabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease

Jacob Tveiten Bjerrum et al.

BMC MEDICINE (2017)

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Urine metabolome profiling of immune-mediated inflammatory diseases

Arnald Alonso et al.

BMC MEDICINE (2016)

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Biologic Therapies and Risk of Infection and Malignancy in Patients With Inflammatory Bowel Disease: A Systematic Review and Network Meta-analysis

Stefanos Bonovas et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2016)

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Reduced Abundance of Butyrate-Producing Bacteria Species in the Fecal Microbial Community in Crohn's Disease

Kenichiro Takahashi et al.

DIGESTION (2016)

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Distinct Microbiotas are Associated with Ileum-Restricted and Colon-Involving Crohn's Disease

Timna Naftali et al.

INFLAMMATORY BOWEL DISEASES (2016)

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Article Nutrition & Dietetics

L-Glutamine Enhances Tight Junction Integrity by Activating CaMK Kinase 2-AMP-Activated Protein Kinase Signaling in Intestinal Porcine Epithelial Cells

Bin Wang et al.

JOURNAL OF NUTRITION (2016)

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The role of acetoacetate in Amadori product formation of human serum albumin

Mousa Bohlooli et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2016)

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Article Microbiology

The predominant site of bacterial translocation across the intestinal mucosal barrier occurs at the advancing disease margin in Crohn's disease

Rodrick J. Chiodini et al.

MICROBIOLOGY-SGM (2016)

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CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

Bruno Lamas et al.

NATURE MEDICINE (2016)

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Bacteriome and Mycobiome Interactions Underscore Microbial Dysbiosis in Familial Crohn's Disease

G. Hoarau et al.

MBIO (2016)

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Disease Severity and Immune Activity Relate to Distinct Interkingdom Gut Microbiome States in Ethnically Distinct Ulcerative Colitis Patients

Jordan S. Mar et al.

MBIO (2016)

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Specialized pro-resolving mediators: endogenous regulators of infection and inflammation

Maria C. Basil et al.

NATURE REVIEWS IMMUNOLOGY (2016)

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A Disease-Associated Microbial and Metabolomics State in Relatives of Pediatric Inflammatory Bowel Disease Patients

Jonathan P. Jacobs et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2016)

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Article Biochemistry & Molecular Biology

Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

Christopher S. Reigstad et al.

FASEB JOURNAL (2015)

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Alterations of mucosal microbiota in the colon of patients with inflammatory bowel disease revealed by real time polymerase chain reaction amplification of 16S ribosomal ribonucleic acid

Jayakanthan Kabeerdoss et al.

INDIAN JOURNAL OF MEDICAL RESEARCH (2015)

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Article Immunology

Adherent-Invasive Escherichia coli Production of Cellulose Influences Iron-Induced Bacterial Aggregation, Phagocytosis, and Induction of Colitis

Melissa Ellermann et al.

INFECTION AND IMMUNITY (2015)

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Article Gastroenterology & Hepatology

Lipidomic Profiling in Inflammatory Bowel Disease: Comparison Between Ulcerative Colitis and Crohn's Disease

Fenling Fan et al.

INFLAMMATORY BOWEL DISEASES (2015)

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Defining the Metabolome: Size, Flux, and Regulation

Nicola Zamboni et al.

MOLECULAR CELL (2015)

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The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease

Yun-Hee Youm et al.

NATURE MEDICINE (2015)

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Decreased Plasma Histidine Level Predicts Risk of Relapse in Patients with Ulcerative Colitis in Remission

Tadakazu Hisamatsu et al.

PLOS ONE (2015)

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Eicosanoid storm in infection and inflammation

Edward A. Dennis et al.

NATURE REVIEWS IMMUNOLOGY (2015)

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The Aryl Hydrocarbon Receptor: Multitasking in the Immune System

Brigitta Stockinger et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 32 (2014)

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Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine

Brianna B. Williams et al.

CELL HOST & MICROBE (2014)

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Article Microbiology

The Treatment-Naive Microbiome in New-Onset Crohn's Disease

Dirk Gevers et al.

CELL HOST & MICROBE (2014)

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A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis

Kathleen Machiels et al.

GUT (2014)

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Article Gastroenterology & Hepatology

Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings

Charlotte R. Hedin et al.

GUT (2014)

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Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

Madhukumar Venkatesh et al.

IMMUNITY (2014)

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Multi-omics analysis of inflammatory bowel disease

Hu Huang et al.

IMMUNOLOGY LETTERS (2014)

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Increased Proportions of Bifidobacterium and the Lactobacillus Group and Loss of Butyrate-Producing Bacteria in Inflammatory Bowel Disease

Wei Wang et al.

JOURNAL OF CLINICAL MICROBIOLOGY (2014)

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A novel gas chromatography mass spectrometry-based serum diagnostic and assessment approach to ulcerative colitis

Michitaka Kohashi et al.

JOURNAL OF CROHNS & COLITIS (2014)

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Succinate: a metabolic signal inflammation

Evanna Mills et al.

TRENDS IN CELL BIOLOGY (2014)

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Ketone bodies as signaling metabolites

John C. Newman et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)

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Serum and urine metabolomic fingerprinting in diagnostics of inflammatory bowel diseases

Tomasz Dawiskiba et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

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Article Genetics & Heredity

Complex host genetics influence the microbiome in inflammatory bowel disease

Dan Knights et al.

GENOME MEDICINE (2014)

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Article Gastroenterology & Hepatology

Colonisation by Faecalibacterium prausnitzii and maintenance of clinical remission in patients with ulcerative colitis

E. Varela et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2013)

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Article Biochemistry & Molecular Biology

1H NMR-based spectroscopy detects metabolic alterations in serum of patients with early-stage ulcerative colitis

Ying Zhang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)

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Clostridium leptum group bacteria abundance and diversity in the fecal microbiota of patients with inflammatory bowel disease: a case-control study in India

Jayakanthan Kabeerdoss et al.

BMC GASTROENTEROLOGY (2013)

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Article Infectious Diseases

The biodiversity and composition of the dominant fecal microbiota in patients with inflammatory bowel disease

Sumei Sha et al.

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2013)

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Article Gastroenterology & Hepatology

Phylogenetic Analysis of Dysbiosis in Ulcerative Colitis During Remission

Mirjana Rajilic-Stojanovic et al.

INFLAMMATORY BOWEL DISEASES (2013)

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Article Gastroenterology & Hepatology

Impact of Ethnicity, Geography, and Disease on the Microbiota in Health and Inflammatory Bowel Disease

Lani Prideaux et al.

INFLAMMATORY BOWEL DISEASES (2013)

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Article Microbiology

Longitudinal Analyses of Gut Mucosal Microbiotas in Ulcerative Colitis in Relation to Patient Age and Disease Severity and Duration

Alemu Fite et al.

JOURNAL OF CLINICAL MICROBIOLOGY (2013)

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Article Gastroenterology & Hepatology

Decreased abundance of Faecalibacterium prausnitzii in the gut microbiota of Crohn's disease

Takehide Fujimoto et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2013)

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Article Multidisciplinary Sciences

A Modular Organization of the Human Intestinal Mucosal Microbiota and Its Association with Inflammatory Bowel Disease

Maomeng Tong et al.

PLOS ONE (2013)

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Article Biochemistry & Molecular Biology

Chronic Immune Stimulation May Cause Moderate Impairment of Phenylalanine 4-hydroxylase

S Scholl-Bürgi et al.

PTERIDINES (2013)

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Article Gastroenterology & Hepatology

Fluctuations in butyrate-producing bacteria in ulcerative colitis patients of North India

Reena Kumari et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2013)

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Article Gastroenterology & Hepatology

Glutamine and Whey Protein Improve Intestinal Permeability and Morphology in Patients with Crohn's Disease: A Randomized Controlled Trial

Jaya Benjamin et al.

DIGESTIVE DISEASES AND SCIENCES (2012)

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Article Gastroenterology & Hepatology

Reduced Diversity and Imbalance of Fecal Microbiota in Patients with Ulcerative Colitis

Hideyuki Nemoto et al.

DIGESTIVE DISEASES AND SCIENCES (2012)

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Article Immunology

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

Ju Qiu et al.

IMMUNITY (2012)

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Article Gastroenterology & Hepatology

Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota

Jane L. Benjamin et al.

INFLAMMATORY BOWEL DISEASES (2012)

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Article Gastroenterology & Hepatology

Alterations in the gut microbiome of children with severe ulcerative colitis

Sonia Michail et al.

INFLAMMATORY BOWEL DISEASES (2012)

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Article Gastroenterology & Hepatology

Urinary NMR metabolomic profiles discriminate inflammatory bowel disease from healthy

Natasha S. Stephens et al.

Journal of Crohns & Colitis (2012)

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Article Biochemical Research Methods

Quantitative Metabolomic Profiling of Serum, Plasma, and Urine by 1H NMR Spectroscopy Discriminates between Patients with Inflammatory Bowel Disease and Healthy Individuals

Rudolf Schicho et al.

JOURNAL OF PROTEOME RESEARCH (2012)

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Article Multidisciplinary Sciences

Novel, Objective, Multivariate Biomarkers Composed of Plasma Amino Acid Profiles for the Diagnosis and Assessment of Inflammatory Bowel Disease

Tadakazu Hisamatsu et al.

PLOS ONE (2012)

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Article Multidisciplinary Sciences

Molecular-Phylogenetic Characterization of the Microbiota in Ulcerated and Non-Ulcerated Regions in the Patients with Crohn's Disease

Qiurong Li et al.

PLOS ONE (2012)

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Article Microbiology

Gram-negative bacteria account for main differences between faecal microbiota from patients with ulcerative colitis and healthy controls

L. K. Vigsnaes et al.

BENEFICIAL MICROBES (2012)

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Article Biotechnology & Applied Microbiology

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

Xochitl C. Morgan et al.

GENOME BIOLOGY (2012)

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Article Microbiology

High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease

Alan W. Walker et al.

BMC MICROBIOLOGY (2011)

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Article Gastroenterology & Hepatology

Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract

Ivan Monteleone et al.

GASTROENTEROLOGY (2011)

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Article Gastroenterology & Hepatology

Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives

Marie Joossens et al.

GUT (2011)

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Article Cell Biology

GC/MS-based profiling of amino acids and TCA cycle-related molecules in ulcerative colitis

Makoto Ooi et al.

INFLAMMATION RESEARCH (2011)

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Article Cell Biology

Amino acids exhibit anti-inflammatory effects in human monocytic leukemia cell line, THP-1 cells

Shunji Hasegawa et al.

INFLAMMATION RESEARCH (2011)

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Review Gastroenterology & Hepatology

New Insights into the Role of Fatty Acids in the Pathogenesis and Resolution of Inflammatory Bowel Disease

Darla R. Shores et al.

INFLAMMATORY BOWEL DISEASES (2011)

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Article Gastroenterology & Hepatology

Highlighting New Phylogenetic Specificities of Crohn's Disease Microbiota

S. Mondot et al.

INFLAMMATORY BOWEL DISEASES (2011)

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Article Multidisciplinary Sciences

The Genome of Akkermansia muciniphila, a Dedicated Intestinal Mucin Degrader, and Its Use in Exploring Intestinal Metagenomes

Mark W. J. van Passel et al.

PLOS ONE (2011)

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Article Multidisciplinary Sciences

Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype

Philipp Rausch et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

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Article Biotechnology & Applied Microbiology

Global genome analysis of the shikimic acid pathway reveals greater gene loss in host-associated than in free-living bacteria

Jurica Zucko et al.

BMC GENOMICS (2010)

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Article Biotechnology & Applied Microbiology

Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes

John H. E. Nash et al.

BMC GENOMICS (2010)

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Article Biochemistry & Molecular Biology

Quantitative Assessment of the Human Gut Microbiome Using Multitag Pyrosequencing

Patrick Gillevet et al.

CHEMISTRY & BIODIVERSITY (2010)

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Article Gastroenterology & Hepatology

A Pyrosequencing Study in Twins Shows That Gastrointestinal Microbial Profiles Vary With Inflammatory Bowel Disease Phenotypes

Ben P. Willing et al.

GASTROENTEROLOGY (2010)

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Article Gastroenterology & Hepatology

Dysbiosis of Fecal Microbiota in Crohn's Disease Patients as Revealed by a Custom Phylogenetic Microarray

Seungha Kang et al.

INFLAMMATORY BOWEL DISEASES (2010)

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Article Pharmacology & Pharmacy

Dyslipidemia and lipoprotein profiles in patients with inflammatory bowel disease

Raja Shekhar R. Sappati Biyyani et al.

JOURNAL OF CLINICAL LIPIDOLOGY (2010)

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Article Microbiology

Transcriptional activity of the dominant gut mucosal microbiota in chronic inflammatory bowel disease patients

Ateequr Rehman et al.

JOURNAL OF MEDICAL MICROBIOLOGY (2010)

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Article Pediatrics

Microbiota in Pediatric Inflammatory Bowel Disease

Andreas Schwiertz et al.

JOURNAL OF PEDIATRICS (2010)

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Article Biochemical Research Methods

Metabonomics in Ulcerative Colitis: Diagnostics, Biomarker Identification, And Insight into the Pathophysiology

Jacob T. Bjerrum et al.

JOURNAL OF PROTEOME RESEARCH (2010)

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Review Biochemistry & Molecular Biology

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

Amar J. Majmundar et al.

MOLECULAR CELL (2010)

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Article Gastroenterology & Hepatology

Faecal microbiota profile of Crohn's disease determined by terminal restriction fragment length polymorphism analysis

A. Andoh et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2009)

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Article Gastroenterology & Hepatology

Dietary Histidine Ameliorates Murine Colitis by Inhibition of Proinflammatory Cytokine Production From Macrophages

Ayatoshi Andou et al.

GASTROENTEROLOGY (2009)

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Article Multidisciplinary Sciences

Metabolomics Reveals Metabolic Biomarkers of Crohn's Disease

Janet Jansson et al.

PLOS ONE (2009)

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Article Gastroenterology & Hepatology

Effects of Glutamine on Proinflammatory Gene Expression and Activation of Nuclear Factor Kappa B and Signal Transducers and Activators of Transcription in TNBS-induced Colitis

Nelson A. Kretzmann et al.

INFLAMMATORY BOWEL DISEASES (2008)

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Article Ecology

Molecular analysis of the gut microbiota of identical twins with Crohn's disease

Johan Dicksved et al.

ISME JOURNAL (2008)

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Article Multidisciplinary Sciences

Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

Daniel N. Frank et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

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Article Nutrition & Dietetics

An overview of phenylalanine and tyrosine kinetics in humans

Dwight E. Matthews

JOURNAL OF NUTRITION (2007)

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Article Microbiology

Structural shifts of mucosa-associated lactobacilli and Clostridium leptum subgroup in patients with ulcerative colitis

Meiling Zhang et al.

JOURNAL OF CLINICAL MICROBIOLOGY (2007)

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Article Biochemical Research Methods

Rapid and noninvasive metabonomic characterization of inflammatory bowel disease

Julian R. Marchesi et al.

JOURNAL OF PROTEOME RESEARCH (2007)

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Article Gastroenterology & Hepatology

Low intestinal glutamine level and low glutaminase activity in Crohn's disease:: a rational for glutamine supplementation?

Bernd Sido et al.

DIGESTIVE DISEASES AND SCIENCES (2006)

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Article Microbiology

Culture-independent analyses of temporal variation of the dominant fecal microbiota and targeted bacterial subgroups in Crohn's disease

Pauline D. Scanlan et al.

JOURNAL OF CLINICAL MICROBIOLOGY (2006)

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Article Microbiology

Inerences between tissue-associated intestinal microfloras of patients with Crohn's disease and ulcerative colitis

Uri Gophna et al.

JOURNAL OF CLINICAL MICROBIOLOGY (2006)

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Article Gastroenterology & Hepatology

The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications

J. Satsangi et al.

GUT (2006)

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Article Gastroenterology & Hepatology

Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach

C Manichanh et al.

GUT (2006)

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Article Biochemistry & Molecular Biology

MAR interacts with occludin and mediates EGF-induced prevention of tight junction disruption by hydrogen peroxide

S Basuroy et al.

BIOCHEMICAL JOURNAL (2006)

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Article Biochemistry & Molecular Biology

Histidine inhibits oxidative stress- and TNF-α-induced interleukin-8 secretion in intestinal epithelial cells

DO Son et al.

FEBS LETTERS (2005)

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Review Cell Biology

Molecular mechanisms of glutamine action

R Curi et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2005)

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Article Gastroenterology & Hepatology

Biodiversity of the mucosa-associated microbiota is stable along the distal digestive tract in healthy individuals and patients with IBD

P Lepage et al.

INFLAMMATORY BOWEL DISEASES (2005)

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Article Gastroenterology & Hepatology

Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer

HM Martin et al.

GASTROENTEROLOGY (2004)

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Article Immunology

Chemotaxonomic analysis of bacterial populations colonizing the rectal mucosa in patients with ulcerative colitis

S Macfarlane et al.

CLINICAL INFECTIOUS DISEASES (2004)

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Article Gastroenterology & Hepatology

Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease

SJ Ott et al.

GUT (2004)

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Article Gastroenterology & Hepatology

Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon

P Seksik et al.

GUT (2003)

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Article Cell Biology

Purine, kynurenine, neopterin and lipid peroxidation levels in inflammatory bowel disease

CM Forrest et al.

JOURNAL OF BIOMEDICAL SCIENCE (2002)

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Review Biochemistry & Molecular Biology

Glutamine and its relationship with intracellular redox status, oxidative stress and cell proliferation/death

JM Matés et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2002)

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Article Immunology

Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing

CN Serhan et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2000)

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Article Nutrition & Dietetics

Altered lipid profile, lipoprotein composition, and oxidant and antioxidant status in pediatric Crohn disease

E Levy et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2000)

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