4.6 Review

Aeromonas and Human Health Disorders: Clinical Approaches

Journal

FRONTIERS IN MICROBIOLOGY
Volume 13, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fmicb.2022.868890

Keywords

microbiology; bacterial infection; human pathogen; prognosis; antibiotic responses

Categories

Funding

  1. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico
  2. Fundacao de Amparo a Ciencia e Tecnologia do Estado de Pernambuco
  3. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior

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Aeromonas is a genus of Gram-negative bacteria that naturally inhabit aquatic environments and are commonly regarded as pathogens of fish and other animals. They have gained attention in medical trials due to their ability to colonize and infect humans. They are widely spread on various sources such as water, soil, vegetables, and food. The main clinical manifestations include gastrointestinal disorders, wound and soft tissue infections, and septicemia. Aeromonas species, such as A. hydrophila, A. caviae, and A. veronii biovar sobria, are considered potential human pathogens. The bacteria show a diversified susceptibility profile and inherent resistance to ampicillin. Further research is needed to fully understand the infectious processes and develop effective approaches for detection and medical intervention.
The genus Aeromonas comprises more than 30 Gram-negative bacterial species and naturally inhabitants from aquatic environments. These microorganisms, commonly regarded as pathogens of fish and several other animals, have been gaining prominence on medical trial due to its ability to colonize and infect human beings. Besides water, Aeromonas are widely spreaded on most varied sources like soil, vegetables, and food; Although its opportunistic nature, they are able to cause infections on immunocompromised or immunocompetent patients. Aeromonas species regarded as potential human pathogens are usually A. hydrophila, A. caviae, and A. veronii biovar sobria. The main clinical manifestations are gastrointestinal tract disorders, wound, and soft tissue infections, as well as septicemia. Regarding to antibiotic responses, the bacteria present a diversified susceptibility profile and show inherence resistance to ampicillin. Aeromonas, as an ascending genus in microbiology, has been carefully studied aiming comprehension and development of methods for detection and medical intervention of infectious processes, not fully elucidated in medicine. This review focuses on current clinical knowledge related to human health disorders caused by Aeromonas to contribute on development of efficient approaches able to recognize and impair the pathological processes.

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