4.2 Review

Substance use screening in transplant populations: Recommendations from a consensus workgroup

Journal

TRANSPLANTATION REVIEWS
Volume 36, Issue 2, Pages -

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.trre.2022.100694

Keywords

Transplantation; Substance use; Screening

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Transplant patients often receive substance treatment and it is necessary to conduct drug testing. This study group reviewed the role of drug testing in patients with substance use disorders and other related issues, and recommended drug testing for transplant patients prior to transplantation for optimal care.
Transplant patients are frequently treated with substances that have dependence potential and/or they may have a history of substance use disorders. The Psychosocial and Ethics Community of Practice of the American Society of Transplantation formed a Drug Testing Workgroup with participation from members of the Pharmacy Com-munity of Practice and members of the Academy of Consultation-Liaison Psychiatry. The workgroup reviewed the literature regarding the following issues: the role of drug testing in patients with substance use disorders, for patients prescribed controlled substances, legal, ethical and prescription drug monitoring issues, financial and insurance issues, and which patients should be tested. We also reviewed current laboratory testing for substances. Group discussions to develop a consensus occurred, and summaries of each topic were reviewed. The workgroup recommends that transplant patients be informed of drug testing and be screened for substances prior to transplant to ensure optimal care and implement ongoing testing if warranted by clinical history. While use of certain substances may not result in the exclusion for transplantation, an awareness of the patient's practices and possible risk from substances is necessary, allowing transplant teams to screen for substance use disorders and ensure the patient is able to manage and minimize risks post-transplant.

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