4.7 Article

Coupled small molecules target RNA interference and JAK/STAT signaling to reduce Zika virus infection in Aedes aegypti

Related references

Note: Only part of the references are listed.
Review Virology

Antiviral Compounds for Blocking Arboviral Transmission in Mosquitoes

Shengzhang Dong et al.

Summary: Mosquito-borne arthropod-borne viruses are important human pathogens with significant global morbidity and mortality, highlighting the need for safe and effective vaccines, therapeutics, and vector-control approaches. Disrupting the virus lifecycle in mosquitoes is a key strategy for combating these diseases, with proposed methods including genetically modified mosquitoes or infection with the symbiotic bacterium Wolbachia.

VIRUSES-BASEL (2021)

Article Entomology

The Genetic Basis for Salivary Gland Barriers to Arboviral Transmission

Irma Sanchez-Vargas et al.

Summary: Mosquito salivary glands can be infected with arboviruses, which are then transmitted through saliva to vertebrate hosts. The infection and escape barriers in salivary glands can modulate arbovirus transmission, and these phenomena are influenced by genetic factors in both the mosquito and the virus.

INSECTS (2021)

News Item Multidisciplinary Sciences

FIRST GENETICALLY MODIFIED MOSQUITOES RELEASED IN THE UNITED STATES

Emily Waltz

NATURE (2021)

Article Microbiology

Sugar feeding protects against arboviral infection by enhancing gut immunity in the mosquito vector Aedes aegypti

Floriane Almire et al.

Summary: Eating sugar can enhance immunity in the gut of Aedes aegypti, the main vector for arboviruses, protecting females from viral infection and reducing transmission potential. These findings suggest that the lack of sugar intake in natural settings may contribute to the spread of mosquito-borne arboviral diseases.

PLOS PATHOGENS (2021)

Review Immunology

Emerging Mechanisms of Insulin-Mediated Antiviral Immunity in Drosophila melanogaster

Chasity E. Trammell et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Biochemistry & Molecular Biology

Upregulation of Aedes aegypti Vago1 by Wolbachia and its effect on dengue virus replication

Sultan Asad et al.

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY (2018)

Article Multidisciplinary Sciences

The RNAi pathway plays a small part in Wolbachia-mediated blocking of dengue virus in mosquito cells

Gerard Terradas et al.

SCIENTIFIC REPORTS (2017)

Article Microbiology

Wolbachia Blocks Currently Circulating Zika Virus Isolates in Brazilian Aedes aegypti Mosquitoes

Heverton Leandro Carneiro Dutra et al.

CELL HOST & MICROBE (2016)

Letter Medicine, General & Internal

Zika virus and hyperglycaemia in pregnancy

Karoline Kragelund Nielsen et al.

LANCET (2016)

Article Parasitology

Mapping the global geographic potential of Zika virus spread

Abdallah M. Samy et al.

MEMORIAS DO INSTITUTO OSWALDO CRUZ (2016)

Article Infectious Diseases

Vector Competence of American Mosquitoes for Three Strains of Zika Virus

James Weger-Lucarelli et al.

PLOS NEGLECTED TROPICAL DISEASES (2016)

Article Multidisciplinary Sciences

The wMel strain of Wolbachia Reduces Transmission of Zika virus by Aedes aegypti

Matthew T. Aliota et al.

SCIENTIFIC REPORTS (2016)

Article Multidisciplinary Sciences

FOXO regulates RNA interference in Drosophila and protects from RNA virus infection

Michael J. Spellberg et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Infectious Diseases

Wolbachia Enhances West Nile Virus (WNV) Infection in the Mosquito Culex tarsalis

Brittany L. Dodson et al.

PLOS NEGLECTED TROPICAL DISEASES (2014)

Article Multidisciplinary Sciences

ERK signaling couples nutrient status to antiviral defense in the insect gut

Jie Xu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Rapid Intraspecific Evolution of miRNA and siRNA Genes in the Mosquito Aedes aegypti

Scott A. Bernhardt et al.

PLOS ONE (2012)

Article Infectious Diseases

C6/36 Aedes albopictus Cells Have a Dysfunctional Antiviral RNA Interference Response

Doug E. Brackney et al.

PLOS NEGLECTED TROPICAL DISEASES (2010)

Article Multidisciplinary Sciences

An evolutionary conserved function of the JAK-STAT pathway in anti-dengue defense

Jayme A. Souza-Neto et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Chemistry, Medicinal

Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors

CW Lindsley et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)