Related references
Note: Only part of the references are listed.Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells
Erik Hedrick et al.
ONCOTARGET (2016)
Peptide Reactivity of Isothiocyanates - Implications for Skin Allergy
Isabella Karlsson et al.
SCIENTIFIC REPORTS (2016)
Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignancies
A. L. Wong et al.
ANNALS OF ONCOLOGY (2015)
Dietary agents for prevention and treatment of lung cancer
Naghma Khan et al.
CANCER LETTERS (2015)
Histone Deacetylase Inhibitors Inhibit Rhabdomyosarcoma by Reactive Oxygen Species-Dependent Targeting of Specificity Protein Transcription Factors
Erik Hedrick et al.
MOLECULAR CANCER THERAPEUTICS (2015)
Prognostic Role of Phospho-STAT3 in Patients with Cancers of the Digestive System: A Systematic Review and Meta-Analysis
Mu-xing Li et al.
PLOS ONE (2015)
AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer
David Hong et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Mechanism of Action of Phenethylisothiocyanate and Other Reactive Oxygen Species-Inducing Anticancer Agents
Indira Jutooru et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
Molecular targets of isothiocyanates in cancer: Recent advances
Parul Gupta et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2014)
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
Hua Yu et al.
NATURE REVIEWS CANCER (2014)
Transcription Factor STAT3 As a Prognostic Marker and Therapeutic Target in Cancer
David A. Frank
JOURNAL OF CLINICAL ONCOLOGY (2013)
MiR-130b Is a Prognostic Marker and Inhibits Cell Proliferation and Invasion in Pancreatic Cancer through Targeting STAT3
Gang Zhao et al.
PLOS ONE (2013)
Celastrol decreases specificity proteins (Sp) and fibroblast growth factor receptor-3 (FGFR3) in bladder cancer cells
Gayathri Chadalapaka et al.
CARCINOGENESIS (2012)
Cancer chemoprevention with dietary isothiocyanates mature for clinical translational research
Shivendra V. Singh et al.
CARCINOGENESIS (2012)
Constitutive activation of STAT3 is predictive of poor prognosis in human gastric cancer
Hua Xiong et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2012)
Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer
K. Kim et al.
ONCOGENE (2012)
The Expression and Clinical Significance of pSTAT3, VEGF and VEGF-C in Pancreatic Adenocarcinoma
C. Huang et al.
NEOPLASMA (2012)
Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors
Sudhakar Chintharlapalli et al.
BMC CANCER (2011)
Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands
Heather M. O'Hagan et al.
CANCER CELL (2011)
Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3
Su-Hyeong Kim et al.
CARCINOGENESIS (2011)
NF-kappa B and STAT3 - key players in liver inflammation and cancer
Guobin He et al.
CELL RESEARCH (2011)
Benzyl Isothiocyanate (BITC) and Phenethyl Isothiocyanate (PEITC)-Mediated Generation of Reactive Oxygen Species Causes Cell Cycle Arrest and Induces Apoptosis via Activation of Caspase-3, Mitochondria Dysfunction and Nitric Oxide (NO) in Human Osteogenic Sarcoma U-2 OS Cells
Chang-Lin Wu et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2011)
GT-094, a NO-NSAID, Inhibits Colon Cancer Cell Growth by Activation of a Reactive Oxygen Species-MicroRNA-27a: ZBTB10-Specificity Protein Pathway
Satya S. Pathi et al.
MOLECULAR CANCER RESEARCH (2011)
Pharmacologic Doses of Ascorbic Acid Repress Specificity Protein (Sp) Transcription Factors and Sp-Regulated Genes in Colon Cancer Cells
Satya S. Pathi et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2011)
Benzyl Isothiocyanate Suppresses Pancreatic Tumor Angiogenesis and Invasion by Inhibiting HIF-α/VEGF/Rho-GTPases: Pivotal Role of STAT-3
Srinivas Reddy Boreddy et al.
PLOS ONE (2011)
Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells
Xiang Wu et al.
BMC CANCER (2010)
Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth
Indira Jutooru et al.
EXPERIMENTAL CELL RESEARCH (2010)
Benzyl Isothiocyanate (BITC) Inhibits Migration and Invasion of Human Colon Cancer HT29 Cells by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase Plasminogen (uPA) through PKC and MAPK Signaling Pathway
Kuang-Chi Lai et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2010)
Inhibition of NFκB and Pancreatic Cancer Cell and Tumor Growth by Curcumin Is Dependent on Specificity Protein Down-regulation
Indira Jutooru et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Drugs that Target Specificity Proteins Downregulate Epidermal Growth Factor Receptor in Bladder Cancer Cells
Gayathri Chadalapaka et al.
MOLECULAR CANCER RESEARCH (2010)
Methyl 2-Cyano-3,12-dioxooleana-1,9-dien-28-oate Decreases Specificity Protein Transcription Factors and Inhibits Pancreatic Tumor Growth: Role of MicroRNA-27a
Indira Jutooru et al.
MOLECULAR PHARMACOLOGY (2010)
Expression of activated signal transducer and activator of transcription 3 predicts poor clinical outcome in gastric adenocarcinoma
Jeeyun Lee et al.
APMIS (2009)
Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells
Ravi P. Sahu et al.
CARCINOGENESIS (2009)
The Role of STAT-3 in the Induction of Apoptosis in Pancreatic Cancer Cells by Benzyl Isothiocyanate
Ravi P. Sahu et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2009)
STATs in cancer inflammation and immunity: a leading role for STAT3
Hua Yu et al.
NATURE REVIEWS CANCER (2009)
Sp1, a new biomarker that identifies a subset of aggressive pancreatic ductal adenocarcinoma
Naomi Y. Jiang et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2008)
STAT3 as a central mediator of neoplastic cellular transformation
David A. Frank
CANCER LETTERS (2007)
Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis
Jane V. Higdon et al.
PHARMACOLOGICAL RESEARCH (2007)
Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak
Dong Xiao et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate
Dunyaporn Trachootham et al.
CANCER CELL (2006)
Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with β-phenylethyl isothiocyanate and curcumin
JH Kim et al.
CARCINOGENESIS (2006)
Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells
L Tang et al.
MOLECULAR CANCER THERAPEUTICS (2005)
Suppression of NF-κB and NF-κB-regulated gene expression by sulforaphane and PEITC through IκBα, IKK pathway in human prostate cancer PC-3 cells
CJ Xu et al.
ONCOGENE (2005)
Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of PC-3 human prostate cancer xenografts in vivo
SK Srivastava et al.
CARCINOGENESIS (2003)
Applicability of a modified Edman procedure for measurement of protein adducts:: Mechanisms of formation and degradation of phenylthiohydantoins
P Rydberg et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2002)
The Stat family in cytokine signaling
JN Ihle
CURRENT OPINION IN CELL BIOLOGY (2001)
Structure and functional analysis of the human STAT3 gene promoter: alteration of chromatin structure as a possible mechanism for the upregulation in cisplatin-resistant cells
K Kato et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2000)
Fruit and vegetable intakes and prostate cancer risk
JH Cohen et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2000)