Native and Indigenous Populations and Gastric Cancer: A Worldwide Review

Gastric cancer is a worldwide concern, particularly for Indigenous populations who face greater disparities in healthcare. With decreased access to screening and critical treatment delays, this group is experiencing adverse health effects. To determine what factors drive these disparities, a systematic review was performed in PubMed. This revealed a lack of research on gastric cancer specific to this population. The literature primarily focused on subset analyses and biological aspects with sparse focus on determinants of health. The results informed this presentation on factors related to Indigenous gastric cancer, which are influenced by colonialism. Indigenous populations encounter high rates of food shortage, exposure to harmful environmental agents, structural racism in the built environment, H. pylori, and compromised healthcare quality as an effect of colonialism, which all contribute to the gastric cancer burden. Putting gastric cancer into a cultural context is a potential means to respond to colonial perspectives and their negative impact on Indigenous patients. The objective of this manuscript is to examine the current state of gastric cancer literature from a global perspective, describe what is currently known based on this literature review, supplemented with additional resources due to lack of published works in PubMed, and to present a model of gastric cancer through the lens of a modified medicine wheel as a potential tool to counter colonial healthcare perspectives and to honor Indigenous culture.

Automated summary

Gastric cancer is a global concern, particularly for Indigenous populations, with limited research specific to this population. Existing literature focuses on subset analyses and biological aspects, with insufficient attention to determinants of health. Indigenous populations face food shortage, exposure to harmful environmental factors, structural racism in the built environment, H. pylori infection, and compromised healthcare as effects of colonialism, contributing to the burden of gastric cancer. Placing gastric cancer in a cultural context can counter colonial perspectives and honor Indigenous culture.