Related references
Note: Only part of the references are listed.Structural insights into TSC complex assembly and GAP activity on Rheb
Huirong Yang et al.
NATURE COMMUNICATIONS (2021)
Loss of Parkin contributes to mitochondrial turnover and dopaminergic neuronal loss in aged mice
Sachiko Noda et al.
NEUROBIOLOGY OF DISEASE (2020)
mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex
Madeline G. Andrews et al.
ELIFE (2020)
Pathological mTOR mutations impact cortical development
Bartosz Tarkowski et al.
HUMAN MOLECULAR GENETICS (2019)
mTOR Hyperactivity Levels Influence the Severity of Epilepsy and Associated Neuropathology in an Experimental Model of Tuberous Sclerosis Complex and Focal Cortical Dysplasia
Lena H. Nguyen et al.
JOURNAL OF NEUROSCIENCE (2019)
Hyperactivation of mTORC1 disrupts cellular homeostasis in cerebellar Purkinje cells
Yusuke Sakai et al.
SCIENTIFIC REPORTS (2019)
GATORopathies: The role of amino acid regulatory gene mutations in epilepsy and cortical malformations
Philip H. Iffland et al.
EPILEPSIA (2019)
mTOR as a central hub of nutrient signalling and cell growth
Joungmok Kim et al.
NATURE CELL BIOLOGY (2019)
ezTrack: An open-source video analysis pipeline for the investigation of animal behavior
Zachary T. Pennington et al.
SCIENTIFIC REPORTS (2019)
Molecular logic of mTORC1 signalling as a metabolic rheostat
Alexander J. Valvezan et al.
NATURE METABOLISM (2019)
dTBC1D7 regulates systemic growth independently of TSC through insulin signaling
Suxia Ren et al.
JOURNAL OF CELL BIOLOGY (2018)
Abnormal mTOR Activation in Autism
Kellen D. Winden et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 41 (2018)
A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility
Christopher J. Yuskaitis et al.
NEUROBIOLOGY OF DISEASE (2018)
Review: Mechanistic target of rapamycin (mTOR) pathway, focal cortical dysplasia and epilepsy
E. Marsan et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2018)
The mTOR pathway in treatment of epilepsy: a clinical update
Jennifer L. Griffith et al.
FUTURE NEUROLOGY (2018)
Essential amino acid ingestion alters expression of genes associated with amino acid sensing, transport, and mTORC1 regulation in human skeletal muscle
Ted G. Graber et al.
NUTRITION & METABOLISM (2017)
Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism
Sameer C. Dhamne et al.
MOLECULAR AUTISM (2017)
mTOR Signaling in Growth, Metabolism, and Disease
Robert A. Saxton et al.
CELL (2017)
The mTOR signalling cascade: paving new roads to cure neurological disease
Peter B. Crino
NATURE REVIEWS NEUROLOGY (2016)
Meta-Analysis of Tourette Syndrome and Attention Deficit Hyperactivity Disorder Provides Support fora Shared Genetic Basis
Fotis Tsetsos et al.
FRONTIERS IN NEUROSCIENCE (2016)
Tuberous sclerosis complex
Elizabeth P. Henske et al.
NATURE REVIEWS DISEASE PRIMERS (2016)
Quantification of gait parameters in freely walking rodents
Cesar S. Mendes et al.
BMC BIOLOGY (2015)
Pten Mutations Alter Brain Growth Trajectory and Allocation of Cell Types through Elevated β-Catenin Signaling
Youjun Chen et al.
JOURNAL OF NEUROSCIENCE (2015)
Complex Neurological Phenotype in Mutant Mice Lacking Tsc2 in Excitatory Neurons of the Developing Forebrain
Beth Crowell et al.
ENEURO (2015)
Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome
Suchithra Menon et al.
CELL (2014)
TBC1D7 Mutations are Associated with Intellectual Disability, Macrocrania, Patellar Dislocation, and Celiac Disease
Ali Abdullah Alfaiz et al.
HUMAN MUTATION (2014)
Selective Activation of mTORC1 Signaling Recapitulates Microcephaly, Tuberous Sclerosis, and Neurodegenerative Diseases
Hidetoshi Kassai et al.
CELL REPORTS (2014)
Comparative Analysis of Tsc1 and Tsc2 Single and Double Radial Glial Cell Mutants
Ulrike Mietzsch et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2013)
Disruption of TBC1D7, a subunit of the TSC1-TSC2 protein complex, in intellectual disability and megalencephaly
Jose-Mario Capo-Chichi et al.
JOURNAL OF MEDICAL GENETICS (2013)
Genome-wide meta-analysis identifies new susceptibility loci for migraine
Verneri Anttila et al.
NATURE GENETICS (2013)
Loss of Tsc2 in Purkinje cells is associated with autistic-like behavior in a mouse model of tuberous sclerosis complex
R. Michelle Reith et al.
NEUROBIOLOGY OF DISEASE (2013)
A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1
Liron Bar-Peled et al.
SCIENCE (2013)
TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1
Christian C. Dibble et al.
MOLECULAR CELL (2012)
Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice
Peter T. Tsai et al.
NATURE (2012)
Fiji: an open-source platform for biological-image analysis
Johannes Schindelin et al.
NATURE METHODS (2012)
Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin
Robert P. Carson et al.
NEUROBIOLOGY OF DISEASE (2012)
Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions
Laura Magri et al.
CELL STEM CELL (2011)
Initiating and Growing an Axon
F. Polleux et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse
Sharon W. Way et al.
HUMAN MOLECULAR GENETICS (2009)
Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
Ling-Hui Zeng et al.
ANNALS OF NEUROLOGY (2008)
Tuberous sclerosis complex proteins control axon formation
Yong-Jin Choi et al.
GENES & DEVELOPMENT (2008)
A mouse model of tuberous sclerosis: Neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival
Lynsey Meikle et al.
JOURNAL OF NEUROSCIENCE (2007)
Muscle atrophy in transgenic mice expressing a human TSC1 transgene
Min Wan et al.
FEBS LETTERS (2006)
The tuberous sclerosis complex
Peter B. Crino et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Loss of autophagy in the central nervous system causes neurodegeneration in mice
Masaaki Komatsu et al.
NATURE (2006)
Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2
SF Tavazoie et al.
NATURE NEUROSCIENCE (2005)
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells
DJ Kwiatkowski et al.
HUMAN MOLECULAR GENETICS (2002)
A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice
T Kobayashi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Share Paper
