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Summary: A study found that recovered individuals, even those with mild cases, may experience persistent symptoms for months after infection, known as long COVID. An integrated analysis of 69 patients recovering from COVID-19 revealed variations in cellular and gene expression levels that may explain the persistence of these long-term effects.
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Jamie Lopez Bernal et al.
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Alex J. Walker et al.
Summary: Recording of long COVID in primary care in England is low and shows significant variation between practices. Possible factors contributing to this include lack of patient presentation, differing diagnostic thresholds among clinicians and patients, and challenges with the design and communication of diagnostic codes. It is recommended to increase awareness of diagnostic codes to support research and service planning, and to conduct qualitative surveys to better understand clinicians' perspectives on diagnosis.
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Javier Garcia-Abellan et al.
Summary: Long-COVID is associated with weak anti-SARS-CoV-2 antibody response, severity of illness, and female gender. Late clinical events and persistent symptoms in the medium and long term occur in a significant proportion of patients hospitalized for COVID-19.
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Summary: Results from the Office for National Statistics COVID-19 Infection Survey in the UK demonstrate that the ChAdOx1 nCoV-19 and BNT162b2 vaccines reduce the incidence of new SARS-CoV-2 infections by up to 65% with a single dose and up to 80% after two doses, with no significant differences in efficacy observed between the two vaccines.
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Ross J. Harris et al.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Meeting Abstract
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Nida Ziauddeen et al.
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Health Care Sciences & Services
Esperanza Miyake et al.
Summary: This study found that the greatest negative impacts on long-term Covid-19 sufferers come mainly from conflicting definitions of the virus and fears surrounding the Covid-19 vaccine. Key areas of concern include time/duration, symptoms/testing, emotional impact, and lack of support and resources.
Review
Public, Environmental & Occupational Health
Melina Michelen et al.
Summary: Long COVID is a complex condition with prolonged and heterogeneous symptoms, including weakness, general malaise, fatigue, concentration impairment, and breathlessness. Approximately 37% of patients reported reduced quality of life, and 26% of studies presented evidence of reduced pulmonary function. There is an urgent need for further studies to explore the etiology, risk factors, and biomarkers of long COVID in different populations and settings.
Article
Medicine, General & Internal
Hannah E. Davis et al.
Summary: Patients with Long COVID report prolonged, multisystem involvement and significant disability. By seven months, many patients have not yet recovered (mainly from systemic and neurological/cognitive symptoms), have not returned to previous levels of work, and continue to experience significant symptom burden.
Article
Public, Environmental & Occupational Health
James Lopez Bernal et al.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
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Article
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Peter C. Austin
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