Experimental Testing of the Action of Vitamin D and Silicon Chelates in Bone Fracture Healing and Bone Turnover in Mice and Rats

Article Biochemistry & Molecular Biology

Inflammatory response of the peripheral neuroendocrine system following downhill running

Andre Luis Araujo Minari et al.

Summary: This study aimed to evaluate the relationship between exercise inflammation and the peripheral neuroendocrine system, finding that increased nAChR receptors may contribute to skeletal muscle adaption after exercise.

CYTOKINE (2022)

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Article Chemistry, Physical

The Mechanism of Mechanochemical Interaction between Amorphous Silicon Dioxide and Pyrocatechol

Elena G. Trofimova et al.

Summary: The study reveals that the solid-phase mechanochemical interaction between pyrocatechol and silicon dioxide leads to the formation of surface complexes, with the interaction efficiency increasing as the number of surface hydroxyl groups rises. Additionally, adding water to the composites can accelerate the formation of soluble silicon chelate complexes.

SILICON (2021)

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Article Nutrition & Dietetics

Vitamin D supplementation reduces the risk of fall in the vitamin D deficient elderly: An updated meta-analysis

Yali Ling et al.

Summary: The combination of vitamin D and calcium has a beneficial effect in preventing falls among elderly individuals, particularly those with 25(OH)D levels lower than 50 nmol/L. Vitamin D supplementation alone does not reduce the risk of falls in elderly individuals with 25(OH)D levels higher than 50 nmol/L.

CLINICAL NUTRITION (2021)

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Review Medicine, Research & Experimental

Silicon: A neglected micronutrient essential for bone health

Mariangela Rondanelli et al.

Summary: Studies have shown a link between silicon and bone mineral density, but there is currently insufficient scientific evidence regarding the role of silicon in human bone health. Based on data from studies on animal and human models, an intake of around 25 mg of silicon per day may be beneficial for bone health. Research on the use of silicon dietary supplements has shown that combined treatment with orthosilicic acid (6 mg), calcium, and vitamin D may have a potentially beneficial effect on femoral bone mineral density compared to using calcium and vitamin D alone.

EXPERIMENTAL BIOLOGY AND MEDICINE (2021)

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Article Nutrition & Dietetics

Vitamin D Dosing: Basic Principles and a Brief Algorithm (2021 Update)

Andrius Bleizgys

Summary: In modern societies, many people may be at risk of low vitamin D levels, so testing serum 25-hydroxy-vitamin D (25OH-D) levels before prescribing supplementation is crucial. In emergency situations, patients should be advised to take moderate vitamin D doses and have their 25-OH-D levels checked later.

NUTRIENTS (2021)

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Article Chemistry, Multidisciplinary

Mechanochemistry as an Alternative Method of Green Synthesis of Silver Nanoparticles with Antibacterial Activity: A Comparative Study

Matej Balaz et al.

Summary: This study compares mechanochemical synthesis and traditional green synthesis methods for silver nanoparticles, finding that mechanochemical synthesis is more effective in removing unreacted silver nitrate. Silver nanoparticles synthesized through green synthesis exhibit higher antibacterial activity, potentially due to the presence of unreacted silver nitrate.

NANOMATERIALS (2021)

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Article Geriatrics & Gerontology

Association between vitamin D status and long-term falls-related hospitalization risk in older women

Marc Sim et al.

Summary: In a cohort of community-dwelling older Australian women aged >= 70 years, higher plasma 25-hydroxyvitamin D levels were associated with a decreased risk of falls-related hospitalizations, indicating that maintaining plasma 25OHD at 75 nmol/L or above may confer benefits to muscle function and long-term prevention of injurious falls requiring hospitalization. This relationship seems to be independent of better physical function observed in women with higher 25OHD levels.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2021)

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Review Nutrition & Dietetics