Journal
NUTRIENTS
Volume 14, Issue 7, Pages -Publisher
MDPI
DOI: 10.3390/nu14071393
Keywords
iodine deficiency; thyroid hormones; pregnancy; supplementation
Categories
Funding
- Portuguese Society for Endocrinology, Diabetes & Metabolism (Bolsa Dra. Maria da Conceicao Barbas/SPEDM-2016)
- Portuguese Foundation for Science and Technology [UIDB/00709/2020]
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Iodine deficiency is a common issue in pregnant women, and supplementation can improve iodine status, although it may not reach the recommended levels in iodine-deficient regions.
Iodine deficiency is a common problem in pregnant women and may have implications for maternal and child health. Iodine supplementation during pregnancy has been recommended by several scientific societies. We undertook a cross-sectional survey to assess the efficacy of these recommendations in a European iodine-deficient region. Urinary iodine concentrations (UIC) were determined in pregnant women before (n = 203) and after (n = 136) the implementation of guidelines for iodine supplementation in pregnancy. Iodine supplementation (200 mu g/day) reduced the proportion of pregnant women with severe iodine deficiency (37.4% to 18.0%, p = 0.0002). The median UIC increased from 67.6 mu g/L to 106.8 mu g/L but remained below the recommended target level (>150 mu g/L) for pregnant women. In conclusion, iodine supplementation in pregnant women improved iodine status in this iodine-deficient region but was insufficient to achieve recommended iodine levels in pregnancy. Additional measures, such as the adjustment of the dose or timing of supplementation, or universal salt iodization, may be needed.
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