Journal
NUTRIENTS
Volume 14, Issue 11, Pages -Publisher
MDPI
DOI: 10.3390/nu14112321
Keywords
dyslipidemia; body measurements; general obesity; central obesity; Chinese adults
Categories
Funding
- National Key Research and Development Program of China [2017YFC0907000]
- High Local Level Discipline Construction Project of Shanghai
- Shanghai New Three-year Action Plan for Public Health [GWV-10.1-XK16]
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This study examined the association between obesity and dyslipidemia among Chinese adults in Shanghai. The study found that participants with obesity had a higher risk of high cholesterol, high triglycerides, high LDL-C, and low HDL-C. Gender, age, hypertension, and diabetes were found to potentially modify this association.
This study examined the association of obesity and dyslipidemia according to body measurements among Chinese adults in Shanghai, a place in the process of rapid urbanization. Using the baseline data of the Shanghai Suburban Adult Cohort and Biobank study (SSACB), the subjects completed questionnaires and physical examinations, and fasting blood was collected for biochemical assays. We estimated the odds ratios (OR) and 95% confidence interval (CI) by multivariable logistic regression. The prevalence was 12.9% and 28.8% in both general and central obesity, respectively. Compared with the non-obese, the general or central obesity participants had a higher level of TC, TG, LDL-C and lower level of HDL-C. The OR (95%CI) for dyslipidemia was 1.79 (1.69-1.91) and 1.91 (1.83-2.00) in general or central obesity, respectively. Positive associations were also observed between obesity and high TC, high LDL-C, low HDL-C and high TG, with the adjusted OR ranging from 1.11 to 2.00. Significant modifying effect of gender, age, hypertension, and diabetes were found in the association of obesity and different forms of dyslipidemia. The findings of our study indicated that participants with obesity, including general or central obesity, have a higher prevalence of dyslipidemia and gender, age, hypertension, and diabetes might be potential modifiers of the association. More effective attention and interventions should be directed to managing body weight to reduce the prevalence of dyslipidemia.
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