Journal
NUTRIENTS
Volume 14, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/nu14061150
Keywords
multiple sclerosis; diet; nutrition; gut-brain axis; gut microbiota
Categories
Funding
- Genesis Pharma via the Institute of Applied Biosciences at the Centre for Research and Technology Hellas (INAB|CERTH) [ESO.0423006]
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This article provides a review of the role of diet in the pathogenesis of multiple sclerosis (MS) and the effects of dietary interventions on MS activity and progression. Research suggests that diet may affect the onset, course, and quality of life in MS patients. Further large prospective clinical studies are needed to thoroughly evaluate the role of diet in MS.
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) characterized by inflammation and neurodegeneration. The most prominent clinical features include visual loss and sensorimotor symptoms and mainly affects those of young age. Some of the factors affecting its pathogenesis are genetic and/or environmental including viruses, smoking, obesity, and nutrition. Current research provides evidence that diet may influence MS onset, course, and quality of life of the patients. In this review, we address the role of nutrition on MS pathogenesis as well as dietary interventions that show promising beneficial results with respect to MS activity and progression. Investigation with large prospective clinical studies is required in order to thoroughly evaluate the role of diet in MS.
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