Partial splenectomy in children undergoing liver transplantation or venous shunt for severe hypersplenism: A case control comparative study

Background and aim: Hypersplenism is a consequence of portal hypertension and splenomegaly secondary to cirrhosis or portal cavernoma in children. In order to avoid persistent hypersplenism and splenomegaly after liver transplantation (LT) or venous shunt (VS), partial splenectomy (PS) may represent a relevant therapeutic option. The aim of this retrospective study was to evaluate the results of PS performed in children presenting hypersplenism.Methods: The following end-points were evaluated: (1) reversion of hypersplenism and its dura-bility over time, (2) postoperative outcome, (3) courses of spleen size and volume and (4) com-parison to a control group in which PS was not performed.

Automated summary

The study aimed to evaluate the results of PS performed in children with hypersplenism, focusing on the reversal of hypersplenism, postoperative outcomes, changes in spleen size and volume, and comparisons to a control group without PS.