Gastrointestinal, hepatic and pancreatic manifestations of COVID-19 in children

Letter Gastroenterology & Hepatology

Gastrointestinal Involvements in Children With COVID-related Multisystem Inflammatory Syndrome

Tai-Heng Chen et al.

GASTROENTEROLOGY (2021)

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Letter Gastroenterology & Hepatology

The Risk of Contracting COVID-19 Is Not Increased in Patients With Celiac Disease

Jamie Zhen et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Letter Gastroenterology & Hepatology

Benign Evolution of SARS-Cov2 Infections in Children With Inflammatory Bowel Disease: Results From Two International Databases

Erica J. Brenner et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Article Gastroenterology & Hepatology

Association of coagulopathy with liver dysfunction in patients with COVID-19

Takeya Tsutsumi et al.

Summary: This study examined 60 COVID-19 patients and found that 52% of patients had high ALT levels, with these patients being obese and having significantly higher levels of D-dimer and fibrin/fibrinogen degradation products. Multivariable analysis showed D-dimer and white blood cells as independent factors.

HEPATOLOGY RESEARCH (2021)

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Article Gastroenterology & Hepatology

Features of Intestinal Disease Associated With COVID-Related Multisystem Inflammatory Syndrome in Children

Benjamin Sahn et al.

Summary: MIS-C is a syndrome recently identified and temporally associated with COVID-19 infection, presenting with fever and systemic inflammation. GI symptoms such as abdominal pain, diarrhea, and vomiting are common, with inflammation predominantly in the ileum and colon leading to bowel wall thickening and potential obstruction. Most cases see resolution with medical therapy, though rare surgical resection may be necessary.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2021)

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Article Immunology

COVID-19 and Multisystem Inflammatory Syndrome in Latin American Children A Multinational Study

Omar Yassef Antunez-Montes et al.

Summary: This study found a more severe form of COVID-19 and a high number of MIS-C cases in Latin American children compared to studies from China, Europe, and North America, indicating a more severe disease in Latin/Hispanic children or those of lower socioeconomic status. There is an urgent need for more data on COVID-19 in Latin America.

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2021)

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Review Pediatrics

COVID-19 infection in children: A systematic review and meta-analysis of clinical features and laboratory findings

M. Mansourian et al.

Summary: This meta-analysis of COVID-19 clinical features and laboratory findings in children found that while children generally have milder symptoms and better prognosis compared to adults, they can still be potential carriers of the virus, emphasizing the importance of early identification and intervention for controlling the pandemic.

ARCHIVES DE PEDIATRIE (2021)

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Article Gastroenterology & Hepatology

Impact of COVID-19 pandemic on the management of paediatric inflammatory bowel disease: An Italian multicentre study on behalf of the SIGENP IBD Group

Serena Arrigo et al.

Summary: The management of pediatric IBD in Italy during the COVID-19 pandemic was significantly impacted by the lockdown, resulting in minimal standards of care prioritizing urgencies and biologic infusions, along with the implementation of telemedicine services.

DIGESTIVE AND LIVER DISEASE (2021)

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Review Gastroenterology & Hepatology

Pathophysiological mechanisms of liver injury in COVID-19

Alexander D. Nardo et al.

Summary: This review discusses the potential mechanisms of hepatic tropism of SARS-CoV-2 and acute, possibly long-term liver injury in COVID-19.

LIVER INTERNATIONAL (2021)

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Article Gastroenterology & Hepatology

High lipasemia is frequent in Covid-19 associated acute respiratory distress syndrome

Sebastian Rasch et al.

Summary: A high level of serum lipase activity is a common finding in severe Covid-19 associated ARDS, without typical signs of acute pancreatitis. The elevated lipase activity may be explained by impaired microcirculation in severely ill patients.

PANCREATOLOGY (2021)

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Letter Gastroenterology & Hepatology

Health status of children with chronic liver disease during the SARS-CoV-2-outbreak: results from a multicentre study''

A. Di Giorgio et al.

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY (2021)

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Review Virology

Gastroenterology manifestations and COVID-19 outcomes: A meta-analysis of 25,252 cohorts among the first and second waves

Rami M. Elshazli et al.

Summary: The meta-analysis revealed that COVID-19 patients presenting with gastrointestinal symptoms had a higher risk of complications such as acute respiratory distress syndrome, acute cardiac injury, and acute kidney injury, as well as a higher chance of ICU admission and mortality. Additionally, patients affected during the first wave of the pandemic had a higher risk of hospitalization, ventilation, ICU admission, and death compared to those in the second wave.

JOURNAL OF MEDICAL VIROLOGY (2021)

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Article Gastroenterology & Hepatology

Severe Acute Respiratory Syndrome Coronavirus-2 Infection in Children With Liver Transplant and Native Liver Disease: An International Observational Registry Study

Mohit Kehar et al.

Summary: Children with native liver disease (LD) and liver transplant (LT) infected with SARS-CoV2 have different outcomes, with LD patients more likely to require hospital admission and pediatric intensive care unit (PICU) management. Patients with nonalcoholic fatty liver disease (NAFLD) and LD had higher odds of severe disease, indicating the need for further studies on effective treatments.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2021)

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Article Gastroenterology & Hepatology

Potential intestinal infection and faecal-oral transmission of SARS-CoV-2

Meng Guo et al.

Summary: SARS-CoV-2, in addition to respiratory transmission, can also cause gastrointestinal symptoms, with detectable RNA in fecal samples of some patients. Infection alters intestinal microbiota, correlated with inflammatory factors. Multiple studies provide evidence of intestinal infection and potential for fecal-oral transmission.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

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Review Pediatrics

COVID-19 in Children With Liver Disease

Angelo Di Giorgio et al.

Summary: Children with chronic liver disease infected with COVID-19 generally have a milder disease course compared to adults. Most children with chronic liver disease remained healthy during the outbreak, even if infected with COVID-19, without experiencing major complications. Additional research is needed to evaluate differences in clinical course between immunosuppressed adults and children, including the concern of asymptomatic infection.

FRONTIERS IN PEDIATRICS (2021)

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Review Pediatrics

SARS-CoV-2 and the Gastrointestinal Tract in Children

Maria Giovanna Puoti et al.

Summary: COVID-19, caused by SARS-CoV-2, not only affects the respiratory system, but also has a significant impact on the gastrointestinal system. The disease enters cells through ACE-2 receptors, which are abundantly expressed in enterocytes. In children, gastrointestinal symptoms may present early and include anorexia, nausea, vomiting, and diarrhea, sometimes leading to severe inflammation such as terminal ileitis.

FRONTIERS IN PEDIATRICS (2021)

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Article Pediatrics

Characteristics and outcomes of neonatal SARS-CoV-2 infection in the UK: a prospective national cohort study using active surveillance

Chris Gale et al.

Summary: This study aimed to describe the incidence, characteristics, transmission, and outcomes of SARS-CoV-2 infection in neonates who received inpatient hospital care in the UK. The findings showed that neonatal SARS-CoV-2 infection was uncommon in babies admitted to hospital, with low likelihood of infection following birth to a mother with perinatal SARS-CoV-2 infection and rare possible vertical transmission. The high proportion of babies from Black, Asian, or minority ethnic groups requires further investigation.

LANCET CHILD & ADOLESCENT HEALTH (2021)

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Article Pediatrics

Multisystem inflammatory syndrome in children (MIS-C) during SARS-CoV-2 pandemic in Brazil: a multicenter, prospective cohort study

Fernanda Lima-Setta et al.

Summary: This study described the clinical, laboratory, and radiological characteristics of children with MIS-C, and found that most patients had similar features to other cohorts. Long-term multidisciplinary follow-up is needed to observe if chronic cardiac impairment or other sequelae may occur in these patients.

JORNAL DE PEDIATRIA (2021)

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Article Medicine, General & Internal

Digestive system symptoms and function in children with COVID-19 A meta-analysis

Jiajia Wang et al.

Summary: This study conducted a meta-analysis to quantify the impact of COVID-19 on the digestive system of children. The results showed that gastrointestinal symptoms and abnormal liver function were not uncommon in children with COVID-19, with diarrhea, nausea or vomiting, abdominal pain, and elevated liver enzymes being the primary manifestations. The recovery rate was as high as 97%, while the mortality rate was only 1%.

MEDICINE (2021)

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Review Gastroenterology & Hepatology

Prevalence and Persistent Shedding of Fecal SARS-CoV-2 RNA in Patients With COVID-19 Infection: A Systematic Review and Meta-analysis

Yawen Zhang et al.

Summary: The study found that fecal SARS-CoV-2 RNA is commonly detected in COVID-19 patients with a 3-fold increased risk in patients with diarrhea. The shedding of fecal RNA lasted more than 3 weeks after presentation and a week after the last detectable respiratory RNA.

CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY (2021)

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Letter Gastroenterology & Hepatology

An International Reporting Registry of Patients With Celiac Disease and COVID-19: Initial Results From SECURE-CELIAC

Eugenia Uche-Anya et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Letter Gastroenterology & Hepatology

Hepatic Vasculopathy and Regenerative Responses of the Liver in Fatal Cases of COVID-19

Barbara Kaltschmidt et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Article Medicine, General & Internal

Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines

Mark G. Thompson et al.

Summary: The study demonstrated that COVID-19 mRNA vaccines were highly effective in preventing SARS-CoV-2 infection in real-world conditions, while also attenuating the viral RNA load, febrile symptoms, and illness duration among vaccinated individuals who had breakthrough infections.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Environmental Sciences

New Onset of Hepatic Steatosis Post-Severe Multisystem Inflammatory Syndrome in Children (MIS-C): A Case Report

Rossella Sica et al.

Summary: SARS-CoV-2 infection may lead to MIS-C, causing multiorgan dysfunction, and subsequent hepatic steatosis in the short term. Close and long-term follow-up is necessary to establish the pathophysiology and evolution of this condition following MIS-C.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

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Review Health Care Sciences & Services

Challenges in Maternal and Child Health Services Delivery and Access during Pandemics or Public Health Disasters in Low-and Middle-Income Countries: A Systematic Review

Krushna Chandra Sahoo et al.

Summary: Maternal and child health services face challenges during public health emergencies, including low utilization, lack of personal safety equipment, and impacted service delivery. More in-depth studies are urgently needed to better understand the true impact of disasters and pandemics on maternal and child health.

HEALTHCARE (2021)

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Article Infectious Diseases

Pancreatitis in Pediatric Patients With COVID-19

Nicole L. Samies et al.

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY (2021)

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Review Pediatrics

Gastrointestinal Manifestations of Pediatric Coronavirus Disease and Their Relationship with a Severe Clinical Course: A Systematic Review and Meta-analysis

Rishi Bolia et al.

Summary: This systematic review on gastrointestinal manifestations of pediatric COVID-19 found that diarrhea is a common symptom and significantly associated with a severe clinical course, whereas abdominal pain and nausea/vomiting are not related to disease severity.

JOURNAL OF TROPICAL PEDIATRICS (2021)

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Article Medicine, General & Internal

Virus discharge and initial gastrointestinal involvement are inversely associated with circulating lymphocyte count in COVID-19

Wei Chen et al.

Summary: The study found that circulating lymphocyte count is inversely associated with virus discharge in stool and the risk of initial gastrointestinal involvement in COVID-19 patients.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2021)

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Article Pediatrics

CLINICAL MANIFESTATIONS OF CHILDREN AND ADOLESCENTS WITH COVID-19: REPORT OF THE FIRST 115 CASES FROM SABARA HOSPITAL INFANTIL

Anna Clara Rabha et al.

Summary: Children and adolescents affected by COVID-19 at Sabara Hospital Infantil mostly presented with mild upper airway symptoms, with younger age groups showing more severe symptoms, particularly gastrointestinal and respiratory symptoms.

REVISTA PAULISTA DE PEDIATRIA (2021)

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Review Pediatrics

Gastrointestinal Manifestations of Pediatric Coronavirus Disease and Their Relationship with a Severe Clinical Course: A Systematic Review and Meta-analysis

Rishi Bolia et al.

Summary: This systematic review found that diarrhea, nausea/vomiting, or abdominal pain are present in nearly one-fifth of children with COVID-19. The presence of diarrhea is significantly associated with a severe clinical course, while abdominal pain and nausea/vomiting are not linked to disease severity.

JOURNAL OF TROPICAL PEDIATRICS (2021)

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Editorial Material Immunology

A Case Series of Children With 2019 Novel Coronavirus Infection: Clinical and Epidemiological Features

Cai Jiehao et al.

CLINICAL INFECTIOUS DISEASES (2020)

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Editorial Material Gastroenterology & Hepatology

Evidence for Gastrointestinal Infection of SARS-CoV-2

Fei Xiao et al.

GASTROENTEROLOGY (2020)

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Article Medicine, General & Internal

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China

Dawei Wang et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

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Article Medicine, General & Internal

Clinical Characteristics of Coronavirus Disease 2019 in China

W. Guan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Gastroenterology & Hepatology

Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study

Lei Pan et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2020)

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Article Cardiac & Cardiovascular Systems

Acute Heart Failure in Multisystem Inflammatory Syndrome in Children in the Context of Global SARS-CoV-2 Pandemic

Zahra Belhadjer et al.

CIRCULATION (2020)

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Letter Gastroenterology & Hepatology

ACE2 Expression in Pancreas May Cause Pancreatic Damage After SARS-CoV-2 Infection

Furong Liu et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2020)

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Article Environmental Sciences

Global Access to Handwashing: Implications for COVID-19 Control in Low-Income Countries

Michael Brauer et al.

ENVIRONMENTAL HEALTH PERSPECTIVES (2020)

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Review Pediatrics

SARS-COV-2 infection in children and newborns: a systematic review

Ilaria Liguoro et al.

EUROPEAN JOURNAL OF PEDIATRICS (2020)

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Article Infectious Diseases

Multicentre Italian study of SARS-CoV-2 infection in children and adolescents, preliminary data as at 10 April 2020

Silvia Garazzino et al.

EUROSURVEILLANCE (2020)

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Article Gastroenterology & Hepatology

Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization

Tao Zuo et al.

GASTROENTEROLOGY (2020)

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Article Gastroenterology & Hepatology

Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples From a Hong Kong Cohort: Systematic Review and Meta-analysis

Ka Shing Cheung et al.

GASTROENTEROLOGY (2020)

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Article Gastroenterology & Hepatology

Digestive system is a potential route of COVID-19: an analysis of single-cell coexpression pattern of key proteins in viral entry process

Hao Zhang et al.

GUT (2020)

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Article Gastroenterology & Hepatology

Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection

Lu Lin et al.

GUT (2020)

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Article Gastroenterology & Hepatology

Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms

Xi Jin et al.

GUT (2020)

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Article Gastroenterology & Hepatology

SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19

Yijin Wang et al.

JOURNAL OF HEPATOLOGY (2020)

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Letter Infectious Diseases

Positive rectal swabs in young patients recovered from coronavirus disease 2019 (COVID-19)

Bin Zhang et al.

JOURNAL OF INFECTION (2020)

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Article Immunology

A 55-Day-Old Female Infant Infected With 2019 Novel Coronavirus Disease: Presenting With Pneumonia, Liver Injury, and Heart Damage

Yuxia Cui et al.

JOURNAL OF INFECTIOUS DISEASES (2020)

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Article Virology

Detectable SARS-CoV-2 viral RNA in feces of three children during recovery period of COVID-19 pneumonia

Tongqiang Zhang et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

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Article Immunology

Do children need a longer time to shed SARS-CoV-2 in stool than adults?

Xiang Ma et al.

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2020)

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Review Immunology

Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019

Yu-Han Xing et al.

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2020)

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Article Pediatrics

Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units

Lara S. Shekerdemian et al.

JAMA PEDIATRICS (2020)

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Letter Gastroenterology & Hepatology

Bilirubin levels in patients with mild and severe Covid-19: A pooled analysis

Panagiotis Paliogiannis et al.

LIVER INTERNATIONAL (2020)

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Article Biochemistry & Molecular Biology

Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding

Yi Xu et al.

NATURE MEDICINE (2020)

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Article Infectious Diseases

Dynamic Viral Severe Acute Respiratory Syndrome Coronavirus 2 RNA Shedding in Children: Preliminary Data and Clinical Consideration from a Italian Regional Center

Maria A. De Ioris et al.

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY (2020)

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Letter Medicine, General & Internal

Children with Covid-19 in Pediatric Emergency Departments in Italy

Niccolo Parri et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Letter Medicine, General & Internal

SARS-CoV-2 Infection in Children

Xiaoxia Lu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Review Gastroenterology & Hepatology

Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis

Ren Mao et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2020)

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Editorial Material Gastroenterology & Hepatology

Liver injury in COVID-19: management and challenges

Chao Zhang et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2020)

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Article Immunology

Symptomatic Infection is Associated with Prolonged Duration of Viral Shedding in Mild Coronavirus Disease 2019: A Retrospective Study of 110 Children in Wuhan

Yingying Lu et al.

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2020)

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Article Pediatrics

Coinfection and Other Clinical Characteristics of COVID-19 in Children

Qin Wu et al.

PEDIATRICS (2020)

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Article Gastroenterology & Hepatology

Lipase Elevation in Patients With COVID-19

Julia McNabb-Baltar et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2020)

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Article Pediatrics

Impact of COVID-19 on diagnosis and management of paediatric inflammatory bowel disease during lockdown: a UK nationwide study

James John Ashton et al.

ARCHIVES OF DISEASE IN CHILDHOOD (2020)

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Editorial Material Gastroenterology & Hepatology

Gastrointestinal Symptoms as a Major Presentation Component of a Novel Multisystem Inflammatory Syndrome in Children That Is Related to Coronavirus Disease 2019: A Single Center Experience of 44 Cases

Jonathan Miller et al.

GASTROENTEROLOGY (2020)

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Article Gastroenterology & Hepatology

Pre-existing liver disease is associated with poor outcome in patients with SARS CoV2 infection; The APCOLIS Study (APASL COVID-19 Liver Injury Spectrum Study)

Shiv Kumar Sarin et al.

HEPATOLOGY INTERNATIONAL (2020)

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Article Gastroenterology & Hepatology

Marked Elevation of Lipase in COVID-19 Disease: A Cohort Study

Usman Barlass et al.

Clinical and Translational Gastroenterology (2020)

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Article Public, Environmental & Occupational Health

Persistence of SARS-CoV-2 virus RNA in feces: A case series of children

Wenjun Du et al.

JOURNAL OF INFECTION AND PUBLIC HEALTH (2020)

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Article Public, Environmental & Occupational Health

COVID-19-Associated Multisystem Inflammatory Syndrome in Children - United States, March-July 2020

Shana Godfred-Cato et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2020)

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Article Pediatrics

Pediatric patients with COVID-19 admitted to intensive care units in Brazil: a prospective multicenter study

Arnaldo Prata-Barbosa et al.

JORNAL DE PEDIATRIA (2020)

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Article Virology

Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China

Yu-pin Tan et al.

JOURNAL OF CLINICAL VIROLOGY (2020)

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Article Pediatrics

COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study

Florian Goetzinger et al.

LANCET CHILD & ADOLESCENT HEALTH (2020)

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Review Medicine, General & Internal

Prevalence of Gastrointestinal Symptoms and Fecal Viral Shedding in Patients With Coronavirus Disease 2019 A Systematic Review and Meta-analysis

Sravanthi Parasa et al.

JAMA NETWORK OPEN (2020)

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Article Medicine, General & Internal

Clinical and Immune Features of Hospitalized Pediatric Patients With Coronavirus Disease 2019 (COVID-19) in Wuhan, China

Huan Wu et al.

JAMA NETWORK OPEN (2020)

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Article Immunology

Clinical and Epidemiological Features of 46 Children <1 Year Old With Coronavirus Disease 2019 in Wuhan, China: A Descriptive Study

Xinghua Liu et al.

JOURNAL OF INFECTIOUS DISEASES (2020)

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Article Virology

Epidemiological features and viral shedding in children with SARS-CoV-2 infection

Chun-Zhen Hua et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

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Article Gastroenterology & Hepatology

COVID-19-associated Multisystem Inflammatory Syndrome in Children Presenting as Acute Pancreatitis

James P. Stevens et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2020)

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Article Gastroenterology & Hepatology

Pediatric Endoscopy in the Era of Coronavirus Disease 2019: A North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper

Catharine M. Walsh et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2020)

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Article Gastroenterology & Hepatology

Corona Virus Disease 2019 and Paediatric Inflammatory Bowel Diseases: Global Experience and Provisional Guidance (March 2020) from the Paediatric IBD Porto Group of European Society of Paediatric Gastroenterology, Hepatology, and Nutrition

Dan Turner et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2020)

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Article Pediatrics

Fulminant hepatic failure: A rare and devastating manifestation of Coronavirus disease 2019 in an 11-year-old boy

E. Haji Esmaeil Memar et al.

ARCHIVES DE PEDIATRIE (2020)

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Review Biochemistry & Molecular Biology

Extrapulmonary manifestations of COVID-19

Aakriti Gupta et al.

NATURE MEDICINE (2020)

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Article Medicine, General & Internal

Multisystem Inflammatory Syndrome in US Children and Adolescents

Leora R. Feldstein et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Medicine, General & Internal

Multisystem Inflammatory Syndrome in Children in New York State

Elizabeth M. Dufort et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Gastroenterology & Hepatology

Acute Hepatitis Is a Prominent Presentation of the Multisystem Inflammatory Syndrome in Children: A Single-Center Report

Amanda Cantor et al.

HEPATOLOGY (2020)

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Letter Clinical Neurology

Liver abnormality may develop cerebral vein thrombosis in COVID-19

S. Aghayari Sheikh Neshin et al.

JOURNAL OF THE NEUROLOGICAL SCIENCES (2020)

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Review Gastroenterology & Hepatology

Coronavirus disease 2019 and the pancreas

Jayanta Samanta et al.

PANCREATOLOGY (2020)

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Article Immunology

Sequelae of COVID-19 in Hospitalized Children: A 4-Months Follow-Up

Marco Denina et al.

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2020)

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Article Immunology

COVID-19 Gastrointestinal Manifestations Are Independent Predictors of PICU Admission in Hospitalized Pediatric Patients

David Gonzalez Jimenez et al.

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2020)

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Article Immunology

Gastrointestinal Symptoms in Severe COVID-19 Children

Vania Giacomet et al.

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2020)

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Article Pediatrics

COVID-19 in 17 Italian Pediatric Emergency Departments

Niccolo Parri et al.

PEDIATRICS (2020)

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Article Medicine, General & Internal

Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study

Olivia Swann et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

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Letter Pediatrics

Abnormal liver enzymes in children and infants withCOVID-19: A narrative review of case-series studies

Yong-Hai Zhou et al.

PEDIATRIC OBESITY (2020)

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Article Critical Care Medicine

Severe manifestations of SARS-CoV-2 in children and adolescents: from COVID-19 pneumonia to multisystem inflammatory syndrome: a multicentre study in pediatric intensive care units in Spain

Alberto Garcia-Salido et al.

CRITICAL CARE (2020)

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Letter Immunology

Viral RNA Load in Mildly Symptomatic and Asymptomatic Children with COVID-19, Seoul, South Korea

Mi Seon Han et al.

EMERGING INFECTIOUS DISEASES (2020)

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Article Immunology

Dynamic surveillance of SARS-CoV-2 shedding and neutralizing antibody in children with COVID-19

Pengcheng Liu et al.

EMERGING MICROBES & INFECTIONS (2020)

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Article Medicine, General & Internal

Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19

Xiao-Yu Wei et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2020)

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Article Gastroenterology & Hepatology

EPC/HPSG evidence-based guidelines for the management of pediatric pancreatitis

Andrea Parniczky et al.

PANCREATOLOGY (2018)

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Review Microbiology

Emerging pathogenic links between microbiota and the gut-lung axis

Kurtis F. Budden et al.

NATURE REVIEWS MICROBIOLOGY (2017)

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Gastrointestinal, hepatic and pancreatic manifestations of COVID-19 in children

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