Microwave assisted green synthesis of Fe@Au core-shell NPs magnetic to enhance olive oil efficiency on eradication of helicobacter pylori (life preserver)

Eco friendly and green synthetic approach for the synthesis of metallic nanoparticles gained much importance in the recent era. In the present study, an environmental friendly and plant mediated synthetic approach was used for the synthesis of gold coated iron (Fe@Au) nanoparticles using extract solution of olive oil, licorice root (Glycyrrhiza glabra) and coconut oil (OLC). These extracts were acted as a reducing agent during the formation of core-shell nanoparticles that provides long-time stability, lower toxicity and higher permeability to specific target cells. In order to achieve the small sized, regular spherical shaped, and homogeneous nanoparticles optimum conditions were ensured. In fact, the use of microwave irradiation was offered higher reaction rate and better product. The Fe@AuNPs have been characterized by UV-Visible spectroscopy, Energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), High resolution Transmission electron microscope (HR-TEM), Fourier Transform Infrared Spectroscopy (FT-IR), highperformance liquid chromatography (HPLC), High angle annular dark-field scanning transmission electron microscopy (HAADF-STEM), Particle-Size Distribution (PSD), and Magnetic hysteresis loops. The synthesized gold coated iron nanoparticles showed significant antioxidant potential with maximum inhibition rates, the biosynthesized nanoparticles were also found effective against Helicobacter pylori (H. pylori) and ulcer.(c) 2022 The Author(s). Published by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Automated summary

In this study, a plant-mediated synthetic method was used to synthesize gold-coated iron nanoparticles. The synthesized nanoparticles showed high stability, low toxicity, and high permeability. Additionally, the nanoparticles exhibited significant antioxidant potential and effectiveness against Helicobacter pylori and ulcers.