Journal
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 18, Issue 6, Pages 535-541Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2015.1121997
Keywords
Rhodomyrtus tomentosa; tomentosone C; myricetin-3,7,3 '-trimethyl ether 5 '-O-beta-glucopyranoside; antimicrobial activity
Funding
- National Natural Science Foundation of China [30973635, 81373293]
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Phytochemical study on the leaves of Rhodomyrtus tomentosa resulted in the isolation of fourteen compounds including a new acylphloroglucinol, named tomentosone C (1), and a new flavonol glycoside, namely myricetin-3,7,3'-trimethyl ether-5'-O-beta glucopyranoside (2). Their structures were characterized by spectral data interpretation for new structures and in comparison with published data for known compounds. The antimicrobial activity evaluation revealed that 1 and the known acylphloroglucinol rhodomyrtone (3) exhibited significant antimicrobial activity with MIC 3.66 and 1.83 mu g ml(-1), respectively, toward Staphylococcus aureus, responsible for the antimicrobial activity observed with the n-hexane and EtOAc-soluble fraction of the ethanol extract of R. tomentosa leaves.
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