4.4 Article

Lipoxygenase-inhibiting lignans from Clematis mandshurica

Journal

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 19, Issue 9, Pages 884-889

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2016.1251419

Keywords

Ranunculaceae; Clematis mandshurica; lignan; lipoxygenase-inhibiting activiy

Funding

  1. National Natural Science fund of China [81503234]

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The EtOH extract of the roots and rhizomes of Clematis mandshurica afforded two new lignans clemomanshurinane C (1) and clemomanshurinane D (2), and three known compounds (3-5). Their structures were elucidated on the basis of spectroscopic means and hydrolysis products. All compounds displayed moderate inhibitory activity against enzyme lipoxygenase. [GRAPHICS] .

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