4.8 Article

Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer

Related references

Note: Only part of the references are listed.
Article Oncology

Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site

Maud Kamal et al.

Summary: This study analyzed the association between different viral integration signatures and clinical parameters in 272 cervical cancer patients, revealing MACROD2 gene as a hotspot of HPV integration. The type of viral integration was dependent on HPV genotype, and a high HPV copy number was associated with longer progression-free survival.

BRITISH JOURNAL OF CANCER (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Biotechnology & Applied Microbiology

Integrated analysis of virus and host transcriptomes in cervical cancer in Asian and Western populations

Qiongzi Qiu et al.

Summary: Race may play a role in influencing vulnerability to HPV variants and cervical cancer prevalence. Integrated analysis of virus and host transcriptomes reveals differences in tumor subtypes and immune infiltration between populations, shedding light on racial disparities in HPV-associated cervical cancers.

GENOMICS (2021)

Article Biochemistry & Molecular Biology

Differences in Stability of Viral and Viral-Cellular Fusion Transcripts in HPV-Induced Cervical Cancers

Franziska Ehrig et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Multidisciplinary Sciences

Patterns of somatic structural variation in human cancer genomes

Yilong Li et al.

NATURE (2020)

Article Oncology

High-resolution copy number analysis of clear cell endometrial carcinoma

Andrea J. O'Hara et al.

CANCER GENETICS (2020)

Review Cell Biology

Colon Cancer-Associated Transcripts 1 and 2: Roles and functions in human cancers

Soudeh Ghafouri-Fard et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Article Biotechnology & Applied Microbiology

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

Daehwan Kim et al.

NATURE BIOTECHNOLOGY (2019)

Article Biotechnology & Applied Microbiology

Modeling double strand break susceptibility to interrogate structural variation in cancer

Tracy J. Ballinger et al.

GENOME BIOLOGY (2019)

Article Biotechnology & Applied Microbiology

Transcriptome assembly from long-read RNA-seq alignments with StringTie2

Sam Kovaka et al.

GENOME BIOLOGY (2019)

Article Biochemical Research Methods

AnnotSV: an integrated tool for structural variations annotation

Veronique Geoffroy et al.

BIOINFORMATICS (2018)

Article Biochemical Research Methods

Accurate detection of complex structural variations using single-molecule sequencing

Fritz J. Sedlazeck et al.

NATURE METHODS (2018)

Article Biochemistry & Molecular Biology

The Papillomavirus Episteme: a major update to the papillomavirus sequence database

Koenraad Van Doorslaer et al.

NUCLEIC ACIDS RESEARCH (2017)

Review Biotechnology & Applied Microbiology

Molecular mechanisms underlying human papillomavirus E6 and E7 oncoprotein-induced cell transformation

Suruchi Mittal et al.

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2017)

Article Multidisciplinary Sciences

Integrated genomic and molecular characterization of cervical cancer

Robert D. Burk et al.

NATURE (2017)

Article Multidisciplinary Sciences

Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity

Kristen M. Turner et al.

NATURE (2017)

Article Microbiology

The role of integration in oncogenic progression of HPV-associated cancers

Alison A. McBride et al.

PLOS PATHOGENS (2017)

Article Oncology

Genomic characterization of viral integration sites in HPV-related cancers

Clara Bodelon et al.

INTERNATIONAL JOURNAL OF CANCER (2016)

Review Oncology

Genomic Landscape of Human Papillomavirus-Associated Cancers

Maria Rusan et al.

CLINICAL CANCER RESEARCH (2015)

Article Biochemistry & Molecular Biology

Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability

Keiko Akagi et al.

GENOME RESEARCH (2014)

Article Multidisciplinary Sciences

Landscape of genomic alterations in cervical carcinomas

Akinyemi I. Ojesina et al.

NATURE (2014)

Article Multidisciplinary Sciences

Characterization of HPV and host genome interactions in primary head and neck cancers

Michael a Parfenov et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Genetics & Heredity

Pan-cancer patterns of somatic copy number alteration

Travis I. Zack et al.

NATURE GENETICS (2013)

Article Multidisciplinary Sciences

The landscape of viral expression and host gene fusion and adaptation in human cancer

Ka-Wei Tang et al.

NATURE COMMUNICATIONS (2013)

Article Endocrinology & Metabolism

SNP Array Profiling of Childhood Adrenocortical Tumors Reveals Distinct Pathways of Tumorigenesis and Highlights Candidate Driver Genes

Eric Letouze et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)

Article Multidisciplinary Sciences

An integrated encyclopedia of DNA elements in the human genome

Ian Dunham et al.

NATURE (2012)

Article Multidisciplinary Sciences

Topological domains in mammalian genomes identified by analysis of chromatin interactions

Jesse R. Dixon et al.

NATURE (2012)

Article Multidisciplinary Sciences

Non-Random Integration of the HPV Genome in Cervical Cancer

Martina Schmitz et al.

PLOS ONE (2012)

Review Oncology

Genomic instability and cancer: Lessons learned from human papillomaviruses

Nina Korzeniewski et al.

CANCER LETTERS (2011)

Article Biochemical Research Methods

BEDTools: a flexible suite of utilities for comparing genomic features

Aaron R. Quinlan et al.

BIOINFORMATICS (2010)

Review Oncology

Pathology and epidemiology of HPV infection in females

Margaret Stanley

GYNECOLOGIC ONCOLOGY (2010)

Article Biochemistry & Molecular Biology

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

Kai Wang et al.

NUCLEIC ACIDS RESEARCH (2010)

Review Oncology

Human papillomavirus oncoproteins: pathways to transformation

Cary A. Moody et al.

NATURE REVIEWS CANCER (2010)

Article Biochemical Research Methods

The Sequence Alignment/Map format and SAMtools

Heng Li et al.

BIOINFORMATICS (2009)

Article Biochemistry & Molecular Biology

Identification of β1,4GalT II as a target gene of p53-mediated HeLa cell apoptosis

Jin Zhou et al.

JOURNAL OF BIOCHEMISTRY (2008)

Article Multidisciplinary Sciences

A second generation human haplotype map of over 3.1 million SNPs

Kelly A. Frazer et al.

NATURE (2007)

Review Medicine, General & Internal

Human papillomavirus and cervical cancer

Mark Schiffman et al.

LANCET (2007)

Article Biochemistry & Molecular Biology

BioGRID: a general repository for interaction datasets

Chris Stark et al.

NUCLEIC ACIDS RESEARCH (2006)

Article Oncology

Carcinogenicity of human papillomaviruses

V Cogliano et al.

LANCET ONCOLOGY (2005)

Review Virology

Classification of papillomaviruses

EM de Villiers et al.

VIROLOGY (2004)

Article Biochemistry & Molecular Biology

Common fragile sites are preferential targets for HPV16 integrations in cervical tumors

EC Thorland et al.

ONCOGENE (2003)

Article Medicine, General & Internal

Epidemiologic classification of human papillomavirus types associated with cervical cancer

N Muñoz et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)