4.8 Article

Supraphysiological activation of TAK1 promotes skeletal muscle growth and mitigates neurogenic atrophy

Related references

Note: Only part of the references are listed.
Review Multidisciplinary Sciences

Mechanisms of muscle atrophy and hypertrophy: implications in health and disease

Roberta Sartori et al.

Summary: Skeletal muscle acts as a protein reservoir in the body and plays a key role in regulating glucose and lipid levels. The growth or loss of muscle mass can impact overall metabolism, movement, eating, and breathing. Various quality systems control muscle function, adapting cells to environmental and nutritional cues.

NATURE COMMUNICATIONS (2021)

Article Geriatrics & Gerontology

TAK1 inhibition improves myoblast differentiation and alleviates fibrosis in a mouse model of Duchenne muscular dystrophy

Dengqiu Xu et al.

Summary: This study found that TAK1 activation worsens fibrosis and muscle degeneration, while TAK1 inhibition can improve muscle quality and function, providing a potential new therapeutic approach for DMD.

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2021)

Review Immunology

TAK1-TABs Complex: A Central Signalosome in Inflammatory Responses

Yan-Ran Xu et al.

Summary: TAK1, a member of the MAPKKK family, functions by assembling with TAB1, TAB2, and TAB3 and can be activated by various stimuli. Post-translational modifications play important roles in controlling the activity, stability, and assembly of the TAK1-TABs complex.

FRONTIERS IN IMMUNOLOGY (2021)

Review Cell Biology

Neuromuscular Development and Disease: Learning From in vitro and in vivo Models

Zachary Fralish et al.

Summary: The neuromuscular junction (NMJ) is a crucial interface between motor neurons and skeletal muscle fibers that is essential for motor function. This review discusses the development of in vitro models of human NMJs derived from induced pluripotent stem cells (hiPSCs) and compares the efficacy of modeling neuromuscular diseases (NMDs) in animals and cell culture systems. Further research is needed to develop effective personalized NMD platforms using hiPSC-derived NMJ models.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Article Cell Biology

Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia

Roberta Sartori et al.

Summary: The study showed that diminished BMP signaling is associated with cancer-induced muscle wasting, and increasing BMP signaling could prevent muscle wasting. This presents an attractive strategy to counteract the loss of functional musculature in cancer patients.

SCIENCE TRANSLATIONAL MEDICINE (2021)

Article Geriatrics & Gerontology

A potential therapeutic effect of catalpol in Duchenne muscular dystrophy revealed by binding with TAK1

Dengqiu Xu et al.

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2020)

Article Biochemistry & Molecular Biology

TAK1 preserves skeletal muscle mass and mitochondrial function through redox homeostasis

Anirban Roy et al.

FASEB BIOADVANCES (2020)

Article Biochemistry & Molecular Biology

PERK regulates skeletal muscle mass and contractile function in adult mice

Yann S. Gallot et al.

FASEB JOURNAL (2019)

Article Multidisciplinary Sciences

mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4

Perrine Castets et al.

NATURE COMMUNICATIONS (2019)

Review Physiology

Revisiting the roles of protein synthesis during skeletal muscle hypertrophy induced by exercise

Vandre Casagrande Figueiredo

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2019)

Article Cell Biology

An embryonic CaVβ1 isoform promotes muscle mass maintenance via GDF5 signaling in adult mouse

Massire Traore et al.

SCIENCE TRANSLATIONAL MEDICINE (2019)

Review Physiology

SARCOPENIA: AGING-RELATED LOSS OF MUSCLE MASS AND FUNCTION

Lars Larsson et al.

PHYSIOLOGICAL REVIEWS (2019)

Article Medicine, General & Internal

Cancer-associated cachexia

Vickie E. Baracos et al.

NATURE REVIEWS DISEASE PRIMERS (2018)

Review Genetics & Heredity

The Role of the Eukaryotic Translation Initiation Factor 4E (eIF4E) in Neuropsychiatric Disorders

Ines S. Amorim et al.

FRONTIERS IN GENETICS (2018)

Article Medicine, Research & Experimental

TAK1 regulates skeletal muscle mass and mitochondrial function

Sajedah M. Hindi et al.

JCI INSIGHT (2018)

Article Biochemistry & Molecular Biology

Novel mechanisms of elF2B action and regulation by elF2α phosphorylation

Andrew M. Bogorad et al.

NUCLEIC ACIDS RESEARCH (2017)

Article Cell Biology

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice

Catherine E. Winbanks et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Review Endocrinology & Metabolism

Bone and morphogenetic protein signalling and muscle mass

Roberta Sartori et al.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2015)

Article Cell Biology

Turnover of acetylcholine receptors at the endplate revisited: novel insights into nerve-dependent behavior

Siegfried Strack et al.

JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2015)

Review Biotechnology & Applied Microbiology

Targeting the translation machinery in cancer

Mamatha Bhat et al.

NATURE REVIEWS DRUG DISCOVERY (2015)

Article Multidisciplinary Sciences

TAK1 modulates satellite stem cell homeostasis and skeletal muscle repair

Yuji Ogura et al.

NATURE COMMUNICATIONS (2015)

Review Biochemistry & Molecular Biology

TAK1 control of cell death

S. R. Mihaly et al.

CELL DEATH AND DIFFERENTIATION (2014)

Review Biochemistry & Molecular Biology

Signaling pathways controlling skeletal muscle mass

Marc A. Egerman et al.

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2014)

Review Endocrinology & Metabolism

TGFβ and BMP signaling in skeletal muscle: potential significance for muscle-related disease

Roberta Sartori et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)

Review Geriatrics & Gerontology

Degeneration of neuromuscular junction in age and dystrophy

Ruediger Rudolf et al.

FRONTIERS IN AGING NEUROSCIENCE (2014)

Article Biochemistry & Molecular Biology

Mechanism and In Vitro Pharmacology of TAK1 Inhibition by (5Z)-7-Oxozeaenol

Jiaquan Wu et al.

ACS CHEMICAL BIOLOGY (2013)

Review Cell Biology

Cellular and molecular mechanisms of muscle atrophy

Paolo Bonaldo et al.

DISEASE MODELS & MECHANISMS (2013)

Article Cell Biology

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

Catherine E. Winbanks et al.

JOURNAL OF CELL BIOLOGY (2013)

Article Genetics & Heredity

BMP signaling controls muscle mass

Roberta Sartori et al.

NATURE GENETICS (2013)

Review Urology & Nephrology

TGF-β Signaling via TAK1 Pathway: Role in Kidney Fibrosis

Mary E. Choi et al.

SEMINARS IN NEPHROLOGY (2012)

Article Multidisciplinary Sciences

TAK1 mediates BMP signaling in cartilage

Matthew B. Greenblatt et al.

SKELETAL BIOLOGY AND MEDICINE (2010)

Article Neurosciences

Differential muscle-driven synaptic remodeling in the neuromuscular junction after denervation

Pessah Yampolsky et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2010)

Review Cell Biology

The mechanism of eukaryotic translation initiation and principles of its regulation

Richard J. Jackson et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Article Cell Biology

Smad2 and 3 transcription factors control muscle mass in adulthood

Roberta Sartori et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2009)

Article Biochemistry & Molecular Biology

TAK1 is an essential regulator of BMP signalling in cartilage

Jae-Hyuck Shim et al.

EMBO JOURNAL (2009)

Review Genetics & Heredity

Nuclear factor-kappa B signaling in skeletal muscle atrophy

Hong Li et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2008)

Article Biochemistry & Molecular Biology

The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming

Todd J. Cohen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation

Philippe P. Roux et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Coping with stress: eIF2 kinases and translational control

RC Wek et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2006)

Review Cell Biology

Smad transcription factors

J Massagué et al.

GENES & DEVELOPMENT (2005)

Article Cell Biology

Wnt/β-catenin signaling activates growth-control genes during overload-induced skeletal muscle hypertrophy

DD Armstrong et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)

Review Biochemistry & Molecular Biology

eIF-4E expression and its role in malignancies and metastases

A De Benedetti et al.

ONCOGENE (2004)

Review Biochemistry & Molecular Biology

eIF4E - from translation to transformation

Y Mamane et al.

ONCOGENE (2004)

Article Biochemistry & Molecular Biology

A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase

J Ninomiya-Tsuji et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

C Wang et al.

NATURE (2001)

Article Biochemistry & Molecular Biology

Phosphorylation-dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1

H Sakurai et al.

FEBS LETTERS (2000)

Article Biochemistry & Molecular Biology

TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop

K Kishimoto et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)