4.6 Article

Clinical efficacy of chitosan-based hydrocolloid dressing in the treatment of chronic refractory wounds

Journal

INTERNATIONAL WOUND JOURNAL
Volume 19, Issue 8, Pages 2012-2018

Publisher

WILEY
DOI: 10.1111/iwj.13801

Keywords

chitosan-based hydrocolloid dressing; chronic refractory wounds; itching; pain; wound healing

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This retrospective study explored the clinical efficacy of chitosan-based hydrocolloid dressing in treating chronic refractory wounds. The results showed that chitosan-based hydrocolloid dressing significantly improved wound healing, reduced pain and itching, and decreased the overall cost and frequency of dressing change.
This retrospective study aimed to explore the clinical efficacy of chitosan-based hydrocolloid dressing in treating chronic refractory wounds. A total of 80 patients with chronic refractory wounds were randomly divided into the control group (n = 40) and the study group (n = 40). The control group was given inert saline gauze, while the study group was given chitosan-based hydrocolloid dressing. After 3 weeks of treatment, the wound healing efficiency, itching pain score, changes in the wound area, dressing change frequency, and cost were measured. There was a significant difference in the wound healing effect (t = 2.738), and degree of pain (t = 4.76) between the study and control groups, after 3 weeks of treatment. Similarly, a prominent reduction in the itching frequency (t = 8.62), and wound area (t = 6.379) was observed in the study group compared to the control group (P < .05). Moreover, the frequency and total cost of dressing change in the study group were also lower than the control group and the difference was statistically significant (P < .05). To summarise, the application of chitosan-based hydrocolloid dressing in treating chronic refractory can effectively alleviate pain, accelerate wound healing, relieve itching pain, and reduce the overall cost and frequency of dressing change.

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