4.7 Article

Porcine circovirus type 2 infection inhibits the activation of type I interferon signaling via capsid protein and host gC1qR

Related references

Note: Only part of the references are listed.
Article Immunology

Leaked Mitochondrial C1QBP Inhibits Activation of the DNA Sensor cGAS

Kun Song et al.

Summary: Pathogen DNA activates cGAS to produce an immune signal, but the mitochondrial protein C1QBP acts as an inhibitor in this process, limiting cGAS function and affecting innate immune responses and HSV-1 infection.

JOURNAL OF IMMUNOLOGY (2021)

Article Microbiology

Porcine circovirus type 2 infection attenuates the K63-linked ubiquitination of STING to inhibit IFN-β induction via p38-MAPK pathway

Xingchen Wu et al.

Summary: PCV2 infection suppresses IFN-beta expression to promote PPV infection in piglets. Additionally, PCV2 activation of p38-MAPK signaling pathway-mediated USP21 phosphorylation inhibits K63 ubiquitination of STING, leading to an increased risk of PPV infection.

VETERINARY MICROBIOLOGY (2021)

Article Microbiology

PCV2 targets cGAS to inhibit type I interferon induction to promote other DNA virus infection

Zhenyu Wang et al.

Summary: PCV2 infection promotes cGAS degradation by activating signaling pathways and regulating protein phosphorylation, which weakens host antiviral immunity and promotes DNA virus infection.

PLOS PATHOGENS (2021)

Review Immunology

Conserved strategies for pathogen evasion of cGAS-STING immunity

James B. Eaglesham et al.

CURRENT OPINION IN IMMUNOLOGY (2020)

Article Multidisciplinary Sciences

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

Lisa Miorin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Virology

Cellular p32 Is a Critical Regulator of Porcine Circovirus Type 2 Nuclear Egress

Tongtong Wang et al.

JOURNAL OF VIROLOGY (2019)

Article Multidisciplinary Sciences

Newcastle Disease Virus V Protein Targets Phosphorylated STAT1 to Block IFN-I Signaling

Xusheng Qiu et al.

PLOS ONE (2016)

Article Virology

No Love Lost Between Viruses and Interferons

Volker Fensterl et al.

ANNUAL REVIEW OF VIROLOGY, VOL 2 (2015)

Review Veterinary Sciences

Porcine circovirus 2 immunology and viral evolution

Tuija Kekarainen et al.

PORCINE HEALTH MANAGEMENT (2015)

Article Biotechnology & Applied Microbiology

Rotavirus inhibits IFN-induced STAT nuclear translocation by a mechanism that acts after STAT binding to importin-α

Gavan Holloway et al.

JOURNAL OF GENERAL VIROLOGY (2014)

Review Immunology

Regulation of type I interferon responses

Lionel B. Ivashkiv et al.

NATURE REVIEWS IMMUNOLOGY (2014)

Article Biotechnology & Applied Microbiology

Porcine Circovirus Type 2 (PCV2): Pathogenesis and Interaction with the Immune System

Xiang-Jin Meng

ANNUAL REVIEW OF ANIMAL BIOSCIENCES, VOL 1 (2013)

Article Gastroenterology & Hepatology

Suppression of interferon-α signaling by hepatitis E virus

Chen Dong et al.

HEPATOLOGY (2012)

Review Virology

Porcine circovirus: Transcription and DNA replication

Andrew K. Cheung

VIRUS RESEARCH (2012)

Review Virology

Immunology of porcine circovirus type 2 (PCV2)

Laila Darwich et al.

VIRUS RESEARCH (2012)

Editorial Material Biochemistry & Molecular Biology

Interferon-Stimulated Genes and Their Protein Products: What and How?

Ernest C. Borden et al.

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2011)

Article Virology

Interferon-stimulated genes and their antiviral effector functions

John W. Schoggins et al.

CURRENT OPINION IN VIROLOGY (2011)

Review Microbiology

Viral tricks to grid-lock the type I interferon system

Gijs A. Versteeg et al.

CURRENT OPINION IN MICROBIOLOGY (2010)

Review Biotechnology & Applied Microbiology

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

Richard E. Randall et al.

JOURNAL OF GENERAL VIROLOGY (2008)

Article Veterinary Sciences

Porcine circoviruses: a minuscule yet mammoth paradox

Sheela Ramamoorthy et al.

ANIMAL HEALTH RESEARCH REVIEWS (2008)

Review Immunology

Recognition of viruses by innate immunity

Osamu Takeuchi et al.

IMMUNOLOGICAL REVIEWS (2007)

Article Virology

Nuclear import and export of Venezuelan equine encephalitis virus nonstructural protein 2

Stephanie A. Montgomery et al.

JOURNAL OF VIROLOGY (2007)

Article Virology

Ebola virus VP24 binds karyopherin α1 and blocks STAT1 nuclear accumulation

St. Patrick Reid et al.

JOURNAL OF VIROLOGY (2006)

Article Multidisciplinary Sciences

A human cytomegalovirus antagonist of type IIFN-dependent signal transducer and activator of transcription signaling

C Paulus et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Immunology

Innate immune recognition of viral infection

T Kawai et al.

NATURE IMMUNOLOGY (2006)

Review Immunology

Mechanisms of type-I- and type-II-interferon-mediated signalling

LC Platanias

NATURE REVIEWS IMMUNOLOGY (2005)

Article Biochemistry & Molecular Biology

Karyopherins and nuclear import

YM Chook et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2001)