Comparison of the effectiveness and duration of anti-RBD SARS-CoV-2 IgG antibody response between different types of vaccines: Implications for vaccine strategies

Article Public, Environmental & Occupational Health

Changes in infectivity, severity and vaccine effectiveness against delta COVID-19 variant ten months into the vaccination program: The Israeli case

Mor Saban et al.

Summary: The epidemiological data on COVID-19 trends in Israel shows that as vaccination coverage increases, there is a significant decrease in infection and hospitalization rates, with a relatively lower death rate. Following the administration of the third vaccine dose, the progression of the pandemic has been somewhat controlled.

PREVENTIVE MEDICINE (2022)

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Article Medicine, General & Internal

Waning Immune Humoral Response to BNT162b2 Covid-19 Vaccine over 6 Months

Einav G. Levin et al.

Summary: A study in Israel revealed that waning immunity after receiving two doses of the BNT162b2 vaccine led to an increase in the incidence of SARS-CoV-2 infection. Levels of spike-binding IgG and neutralizing antibodies decreased more significantly in men, individuals aged 65 or older, and immunosuppressed individuals in a longitudinal study involving nearly 4000 healthcare workers.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Public, Environmental & Occupational Health

A three-phase population based sero-epidemiological study: Assessing the trend in prevalence of SARS-CoV-2 during COVID-19 pandemic in Jordan

Saverio Bellizzi et al.

Summary: The evolution of the COVID-19 pandemic in Jordan went through three distinct phases, with a nationwide sero-prevalence survey showing a rapid increase in seroprevalence over time, reaching one-third of the population exposed to the virus by the end of 2020. Non-age-specific trends were observed in infection rates, with the majority of infected individuals being asymptomatic. The insights gained from serial cross-sectional surveys in Jordan will be valuable for planning public health mitigation measures like vaccinations and tailored restriction policies.

ONE HEALTH (2021)

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Article Medicine, General & Internal

Evolution of antibody responses up to 13 months after SARS-CoV-2 infection and risk of reinfection

Floriane Gallais et al.

Summary: The study revealed a triphasic kinetic model of SARS-CoV-2 antibodies in convalescent individuals, showing long-term persistence and reduced risk of reinfection. Vaccination significantly increased antibody titers, enhancing protection against variants.

EBIOMEDICINE (2021)

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Article Immunology

Neutralizing Anti-SARS-CoV-2 Antibody Titer and Reported Adverse Effects, in a Sample of Italian Nursing Home Personnel after Two Doses of the BNT162b2 Vaccine Administered Four Weeks Apart

Alberto Modenese et al.

Summary: A study conducted on healthcare workers at a nursing home in Northern Italy showed that all workers had high antibody titers after receiving two doses of the BNT162b2 vaccine, even when administered four weeks apart. Adverse effects were more common after the second dose, but there were no severe adverse effects observed.

VACCINES (2021)

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Article Microbiology

Differential Antibody Response to mRNA COVID-19 Vaccines in Healthy Subjects

Sarah E. Wheeler et al.

Summary: Understanding the development and duration of virus-specific antibodies after COVID-19 vaccination is important for controlling the pandemic. Postvaccination antibody testing can help in monitoring individuals after vaccination and selecting those who may require additional doses or not need vaccination.

MICROBIOLOGY SPECTRUM (2021)

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Editorial Material Microbiology