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Imaging the Tumor Microenvironment

Journal

CANCER JOURNAL
Volume 21, Issue 3, Pages 174-178

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/PPO.0000000000000118

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Funding

  1. NIH/NCI CCSG [P30CA016672]
  2. UT MDACC Khalifa Bin Zayed Al Nahya Foundation
  3. U.S. Department of Energy (DOE) [DE-SC0008833] Funding Source: U.S. Department of Energy (DOE)

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The tumor microenvironment (TME) is a complex, heterogeneous, and dominant component of solid tumors. Cancer imaging strategies of a subset of characteristics of the TME are under active development, and currently used modalities and novel approaches are summarized in this article. Understanding the dynamic and evolving functions of the TME is critical to accurately inform imaging and clinical care of cancer. Novel insights into distinct roles of the TME in cancer progression urge careful interpretation of imaging data and impel the development of novel modalities.

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