Circular biomanufacturing through harvesting solar energy and CO2

Using synthetic biology, it is now time to expand the biosynthetic repertoire of plants and microalgae by utilizing the chloroplast to augment the production of desired high-value compounds and of oil-, carbohydrate-, or protein-enriched biomass based on direct harvesting of solar energy and the consumption of CO2. Multistream product lines based on separate commercialization of the isolated high-value compounds and of the improved bulk products increase the economic potential of the light-driven production system and accelerate commercial scale up. Here we outline the scientific basis for the establishment of such green circular biomanufacturing systems and highlight recent results that make this a realistic option based on cross-disciplinary basic and applied research to advance long-term solutions.

Automated summary

By utilizing synthetic biology, it is now possible to expand the biosynthetic repertoire of plants and microalgae by using the chloroplast to increase the production of desired compounds. Separate commercialization of high-value compounds and improved bulk products can increase the economic potential and accelerate commercialization of the production system.