Related references
Note: Only part of the references are listed.BBPpred: Sequence-Based Prediction of Blood-Brain Barrier Peptides with Feature Representation Learning and Logistic Regression
Ruyu Dai et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2021)
Transplantation of human dental pulp stem cells compensates for striatal atrophy and modulates neuro-inflammation in 3-nitropropionic acid rat model of Huntington's disease
Neda Eskandari et al.
NEUROSCIENCE RESEARCH (2021)
An Outside-In and Inside-Out Consideration of Complement in the Multiple Sclerosis Brain: Lessons From Development and Neurodegenerative Diseases
B. Paul Morgan et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2021)
The complement system in age-related macular degeneration
Angela Armento et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2021)
Targeting the complement system in neuromyelitis optica spectrum disorder
Nithi Asavapanumas et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2021)
Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics
Peter Garred et al.
PHARMACOLOGICAL REVIEWS (2021)
The Impact of Complement Genes on the Risk of Late-Onset Alzheimer's Disease
Sarah M. Carpanini et al.
GENES (2021)
Brain Disposition of Antibody-Based Therapeutics: Dogma, Approaches and Perspectives
Aida Kouhi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity
Emil Gregersen et al.
JOURNAL OF NEUROINFLAMMATION (2021)
LANDMARK ALZHEIMER'S DRUG APPROVAL CONFOUNDS RESEARCH COMMUNITY
Asher Mullard
NATURE (2021)
Convection-Enhanced Delivery and Principles of Extracellular Transport in the Brain
Amir H. Faraji et al.
WORLD NEUROSURGERY (2021)
The Role of Complement in Synaptic Pruning and Neurodegeneration
Angela Gomez-Arboledas et al.
IMMUNOTARGETS AND THERAPY (2021)
Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS
Sarah Waters et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2021)
Estimated Prevalence and Incidence of Amyotrophic Lateral Sclerosis and SOD1 and C9orf72 Genetic Variants
Carolyn A. Brown et al.
NEUROEPIDEMIOLOGY (2021)
Cerebrospinal fluid complement system biomarkers in demyelinating disease
Wioleta Milena Zelek et al.
MULTIPLE SCLEROSIS JOURNAL (2020)
Complement-dependent synapse loss and microgliosis in a mouse model of multiple sclerosis
Jennetta W. Hammond et al.
BRAIN BEHAVIOR AND IMMUNITY (2020)
Complement-Mediated Events in Alzheimer's Disease: Mechanisms and Potential Therapeutic Targets
Andrea J. Tenner
JOURNAL OF IMMUNOLOGY (2020)
The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration
Anne-Laure Mahul-Mellier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Blood-Brain Barrier and Delivery of Protein and Gene Therapeutics to Brain
William M. Pardridge
FRONTIERS IN AGING NEUROSCIENCE (2020)
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys
Mihalis S. Kariolis et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
The good, the bad, and the opportunities of the complement system in neurodegenerative disease
Nicole D. Schartz et al.
JOURNAL OF NEUROINFLAMMATION (2020)
Blood-Brain Barrier Leakage Is Increased in Parkinson's Disease
Sarah Al-Bachari et al.
FRONTIERS IN PHYSIOLOGY (2020)
Monoclonal Antibodies Capable of Inhibiting Complement Downstream of C5 in Multiple Species
Wioleta M. Zelek et al.
FRONTIERS IN IMMUNOLOGY (2020)
Risk Analysis of Eculizumab-Related Meningococcal Disease in Japan Using the Japanese Adverse Drug Event Report Database
Yumi Matsumura
DRUG HEALTHCARE AND PATIENT SAFETY (2020)
Inflammation in Huntington's disease: A few new twists on an old tale
Priscila Aparecida Costa Valadao et al.
JOURNAL OF NEUROIMMUNOLOGY (2020)
Inflammatory biomarkers in Alzheimer's disease plasma
Angharad R. Morgan et al.
ALZHEIMERS & DEMENTIA (2019)
Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome
Dario Tejera et al.
EMBO JOURNAL (2019)
Cognitive Impairment in Neuromyelitis Optica Spectrum Disorders: A Review of Clinical and Neuroradiological Features
Frederike Cosima Oertel et al.
FRONTIERS IN NEUROLOGY (2019)
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay
Liu Shi et al.
ALZHEIMERS & DEMENTIA (2019)
Compendium of current complement therapeutics
Wioleta M. Zelek et al.
MOLECULAR IMMUNOLOGY (2019)
Recombinant expressing angiopep-2 fused anti-VEGF single chain Fab (scFab) could cross blood-brain barrier and target glioma
Xuemei Ji et al.
AMB EXPRESS (2019)
Water-exchange MRI detects subtle blood-brain barrier breakdown in Alzheimer's disease rats
Ben R. Dickie et al.
NEUROIMAGE (2019)
Therapeutic Inhibition of the Complement System in Diseases of the Central Nervous System
Sarah M. Carpanini et al.
FRONTIERS IN IMMUNOLOGY (2019)
Amyotrophic lateral sclerosis: The complement and inflammatory hypothesis
Anne-Lene Kjaeldgaard et al.
MOLECULAR IMMUNOLOGY (2018)
MRI measurements of Blood-Brain Barrier function in dementia: A review of recent studies
Rajikha Raja et al.
NEUROPHARMACOLOGY (2018)
Current Strategies for Brain Drug Delivery
Xiaowei Dong
THERANOSTICS (2018)
Low-grade systemic inflammation is associated with functional disability in elderly people affected by dementia
Carlo Cervellati et al.
GEROSCIENCE (2018)
Plasma complement biomarkers distinguish multiple sclerosis and neuromyelitis optica spectrum disorder
Svetlana Hakobyan et al.
MULTIPLE SCLEROSIS JOURNAL (2017)
Huntington's Disease: Mechanisms of Pathogenesis and Therapeutic Strategies
Maria Jimenez-Sanchez et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Plasma complement biomarkers distinguish multiple sclerosis and neuromyelitis optica spectrum disorder
Svetlana Hakobyan et al.
MULTIPLE SCLEROSIS JOURNAL (2017)
The Correlation between Inflammatory Biomarkers and Polygenic Risk Score in Alzheimer's Disease
Angharad R. Morgan et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Routes for Drug Translocation Across the Blood-Brain Barrier: Exploiting Peptides as Delivery Vectors
Mie Kristensen et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice
Qiaoqiao Shi et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Delivery of Biologics Across the Blood-Brain Barrier with Molecular Trojan Horse Technology
William M. Pardridge
BIODRUGS (2017)
Cationization increases brain distribution of an amyloid-beta protofibril selective F(ab')2 fragment
Stina Syvanen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Inflammation in Alzheimer's disease: Lessons learned from microglia-depletion models
Elizabeth E. Spangenberg et al.
BRAIN BEHAVIOR AND IMMUNITY (2017)
Blood-brain barrier shuttle peptides: an emerging paradigm for brain delivery
Benjami Oller-Salvia et al.
CHEMICAL SOCIETY REVIEWS (2016)
Diagnosis and Treatment of Central Nervous System Infections in the Emergency Department
Maia Dorsett et al.
EMERGENCY MEDICINE CLINICS OF NORTH AMERICA (2016)
The membrane attack complex as an inflammatory trigger
B. Paul Morgan
IMMUNOBIOLOGY (2016)
Complement is activated in progressive multiple sclerosis cortical grey matter lesions
Lewis M. Watkins et al.
JOURNAL OF NEUROINFLAMMATION (2016)
Complement and microglia mediate early synapse loss in Alzheimer mouse models
Soyon Hong et al.
SCIENCE (2016)
Complement C1q-C3-associated synaptic changes in multiple sclerosis hippocampus
Iliana Michailidou et al.
ANNALS OF NEUROLOGY (2015)
Systemic inflammation and microglial activation: systematic review of animal experiments
Inge C. M. Hoogland et al.
JOURNAL OF NEUROINFLAMMATION (2015)
Complement, a target for therapy in inflammatory and degenerative diseases
B. Paul Morgan et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
Claudio Franceschi et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
Complement activation in multiple sclerosis plaques: an immunohistochemical analysis
Gillian Ingram et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2013)
Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration
V. Hugh Perry et al.
SEMINARS IN IMMUNOPATHOLOGY (2013)
Complement dysregulation and disease: From genes and proteins to diagnostics and drugs
Santiago Rodriguez de Cordoba et al.
IMMUNOBIOLOGY (2012)
Aquaporin 4 and neuromyelitis optica
Marios C. Papadopoulos et al.
LANCET NEUROLOGY (2012)
Systemic complement profiling in multiple sclerosis as a biomarker of disease state
G. Ingram et al.
MULTIPLE SCLEROSIS JOURNAL (2012)
Targeted inhibition of complement using complement receptor 2-conjugated inhibitors attenuates EAE
Xianzhen Hu et al.
NEUROSCIENCE LETTERS (2012)
Complement upregulation and activation on motor neurons and neuromuscular junction in the SOD1 G93A mouse model of familial amyotrophic lateral sclerosis
Bianca Heurich et al.
JOURNAL OF NEUROIMMUNOLOGY (2011)
Complement in the brain
Robert Veerhuis et al.
MOLECULAR IMMUNOLOGY (2011)
Innate and adaptive immunity in amyotrophic lateral sclerosis: Evidence of complement activation
M. Sta et al.
NEUROBIOLOGY OF DISEASE (2011)
A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-β Production in Vivo
Jasvinder K. Atwal et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target
Y. Joy Yu et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Penetration of Drugs through the Blood-Cerebrospinal Fluid/Blood-Brain Barrier for Treatment of Central Nervous System Infections
Roland Nau et al.
CLINICAL MICROBIOLOGY REVIEWS (2010)
Involvement of Immune Response in the Pathogenesis of Amyotrophic Lateral Sclerosis: A Therapeutic Opportunity?
A. Calvo et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2010)
Immunoglobulins and Complement in Postmortem Multiple Sclerosis Tissue
Michael H. Barnett et al.
ANNALS OF NEUROLOGY (2009)
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2009)
The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral Sclerosis
Trent M. Woodruff et al.
JOURNAL OF IMMUNOLOGY (2008)
Complement C3 deficiency leads to accelerated amyloid β plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice
Marcel Maier et al.
JOURNAL OF NEUROSCIENCE (2008)
Complement activation in the Parkinson's disease substantia nigra: an immunocytochemical study
David A. Loeffler et al.
JOURNAL OF NEUROINFLAMMATION (2006)
Inflammation, the complement system and the diseases of aging
EG McGeer et al.
NEUROBIOLOGY OF AGING (2005)
A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis
VA Lennon et al.
LANCET (2004)
High transcytosis of melanotransferrin (P97) across the blood brain barrier
M Demeule et al.
JOURNAL OF NEUROCHEMISTRY (2002)
The overlap of amyotrophic lateral sclerosis and frontotemporal dementia
C Lomen-Hoerth et al.
NEUROLOGY (2002)
β-amyloid fibrils activate the C1 complex of complement under physiological conditions:: Evidence for a binding site for Aβ on the C1q globular regions
P Tacnet-Delorme et al.
JOURNAL OF IMMUNOLOGY (2001)
Advances in osmotic opening of the blood-brain barrier to enhance CNS chemotherapy
SI Rapoport
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2001)