A new Down syndrome rat model races forward

Animal models of Down syndrome (DS) provide an essential resource for understanding genetic, cellular, and molecular contributions to traits associated with trisomy 21 (Ts21). Recent genetic enhancements in the development of DS models, including the new TcHSA21rat model (Kazuki et al.), have potential to transform our understanding of and potential therapies for Ts21.

Automated summary

Animal models of Down syndrome are crucial for studying the genetic, cellular, and molecular factors contributing to traits associated with trisomy 21. Recent advancements in genetic enhancements, such as the TcHSA21rat model, have the potential to revolutionize our understanding of and potential therapies for Down syndrome.