4.4 Article

Total Synthesis of (+)-Tabertinggine

Journal

TETRAHEDRON
Volume 115, Issue -, Pages -

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2022.132781

Keywords

Chiral pool; Pictet-spengler reaction; Total synthesis

Funding

  1. National Natural Science Foundation of China [21732001, 21871118, 22071090, IRT_15R28]

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A concise total synthesis of (+)-tabertinggine was achieved in 12 steps with an overall yield of 6.1% through a Pictet-Spengler condensation/lactamization cascade reaction.
A concise total synthesis of (+)-tabertinggine was accomplished in 12 steps with 6.1% overall yield enabled by a Pictet-Spengler condensation/lactamization cascade reaction. (C) 2022 Elsevier Ltd. All rights reserved.

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