Related references
Note: Only part of the references are listed.Targeting intrinsically disordered proteins involved in cancer
Patricia Santofimia-Castano et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2020)
High intracellular stability of the spidroin N-terminal domain in spite of abundant amyloidogenic segments revealed by in-cell hydrogen/deuterium exchange mass spectrometry
Margit Kaldmae et al.
FEBS JOURNAL (2020)
Proteome-wide observation of the phenomenon of life on the edge of solubility
Giulia Vecchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
High-yield Production of Amyloid-β Peptide Enabled by a Customized Spider Silk Domain
Axel Abelein et al.
SCIENTIFIC REPORTS (2020)
Structure Determination of the Transactivation Domain of p53 in Complex with S100A4 Using Annexin A2 as a Crystallization Chaperone
Peter Ecsedi et al.
STRUCTURE (2020)
Tumor-Suppressor p53TAD1-60Forms a Fuzzy Complex with Metastasis-Associated S100A4: Structural Insights and Dynamics by an NMR/MD Approach
Erika F. Dudas et al.
CHEMBIOCHEM (2020)
Unique insights to intrinsically disordered proteins provided by ion mobility mass spectrometry
Dale Stuchfield et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2018)
A spidroin-derived solubility tag enables controlled aggregation of a designed amyloid protein
Medoune Sarr et al.
FEBS JOURNAL (2018)
Targeting Intrinsically Disordered Transcription Factors: Changing the Paradigm
K. Tsafou et al.
JOURNAL OF MOLECULAR BIOLOGY (2018)
Targeting mutant p53 for efficient cancer therapy
Vladimir J. N. Bykov et al.
NATURE REVIEWS CANCER (2018)
The Nephila clavipes genome highlights the diversity of spider silk genes and their complex expression
Paul L. Babb et al.
NATURE GENETICS (2017)
eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences
Vicent Pelechano et al.
NUCLEIC ACIDS RESEARCH (2017)
Translation and folding of single proteins in real time
Florian Wruck et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Efficient protein production inspired by how spiders make silk
Nina Kronqvist et al.
NATURE COMMUNICATIONS (2017)
The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches
Andreas C. Joerger et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 85 (2016)
Molecular insights into protein synthesis with proline residues
Sergey Melnikov et al.
EMBO REPORTS (2016)
Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein
Alexander S. Krois et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
James A. Maier et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
Pharmacological reactivation of p53 as a strategy to treat cancer
J. Zawacka-Pankau et al.
JOURNAL OF INTERNAL MEDICINE (2015)
Ensemble Methods Enable a New Definition for the Solution to Gas-Phase Transfer of Intrinsically Disordered Proteins
Antoni J. Borysik et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Mechanical force releases nascent chain-mediated ribosome arrest in vitro and in vivo
Daniel H. Goldman et al.
SCIENCE (2015)
Collision Cross Sections for Structural Proteomics
Erik G. Marklund et al.
STRUCTURE (2015)
Quantifying the stabilizing effects of protein-ligand interactions in the gas phase
Timothy M. Allison et al.
NATURE COMMUNICATIONS (2015)
Cotranslational Protein Folding inside the Ribosome Exit Tunnel
Ola B. Nilsson et al.
CELL REPORTS (2015)
Conformation transitions of eukaryotic polyribosomes during multi-round translation
Zhanna A. Afonina et al.
NUCLEIC ACIDS RESEARCH (2015)
Prion-like aggregation of mutant p53 in cancer
Jerson L. Silva et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation
Nina Kronqvist et al.
NATURE COMMUNICATIONS (2014)
Intrinsically Disordered Segments Affect Protein Half-Life in the Cell and during Evolution
Robin van der Lee et al.
CELL REPORTS (2014)
Stapled Peptides with Improved Potency and Specificity That Activate p53
Christopher J. Brown et al.
ACS CHEMICAL BIOLOGY (2013)
elF5A Promotes Translation of Polyproline Motifs
Erik Gutierrez et al.
MOLECULAR CELL (2013)
Stapled α-helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy
Yong S. Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Using chemical shift perturbation to characterise ligand binding
Mike P. Williamson
PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (2013)
The Tetramer of p53 in the Absence of DNA Forms a Relaxed Quaternary State
Nam Pham et al.
BIOCHEMISTRY (2012)
pH-Dependent Dimerization of Spider Silk N-Terminal Domain Requires Relocation of a Wedged Tryptophan Side Chain
Kristaps Jaudzems et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
Prevention of overfitting in cryo-EM structure determination
Sjors H. W. Scheres et al.
NATURE METHODS (2012)
A pH-Dependent Dimer Lock in Spider Silk Protein
Michael Landreh et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Crystal Structure of the p53 Core Domain Bound to a Full Consensus Site as a Self-Assembled Tetramer
Yongheng Chen et al.
STRUCTURE (2010)
Slow peptide bond formation by proline and other N-alkylamino acids in translation
Michael Y. Pavlov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Intrinsically disordered proteins in human diseases: Introducing the D-2 concept
Vladimir N. Uversky et al.
ANNUAL REVIEW OF BIOPHYSICS (2008)
Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain
Mark Wells et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
EMAN2: An extensible image processing suite for electron microscopy
Guang Tang et al.
JOURNAL OF STRUCTURAL BIOLOGY (2007)
A novel eIF5A complex functions as a regulator of p53 and p53-dependent apoptosis
AL Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy
PB Rosenthal et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)