4.7 Article

A biomarker (ONOO-)-activated multicolor fluorescent probe for early detection and assessment of arthritis

Related references

Note: Only part of the references are listed.
Article Chemistry, Analytical

Indication of Dynamic Peroxynitrite Fluctuations in the Rat Epilepsy Model with a Near-Infrared Two-Photon Fluorescent Probe

Xianzhu Luo et al.

Summary: Epilepsy pathology is closely related to peroxynitrite. A newly developed fluorescent probe can effectively trace and detect the changes of ONOO- in the epileptic brain, facilitating the understanding of epilepsy pathology and diagnosis.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Analytical

Monitoring the Fluctuation of Hydrogen Peroxide in Diabetes and Its Complications with a Novel Near-Infrared Fluorescent Probe

Wen-Xin Wang et al.

Summary: The novel fluorescent probe QX-B shows high sensitivity and excellent selectivity in detecting H2O2 in diabetic mice, with low cytotoxicity in cells.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Xanthene-Based NIR-II Dyes for In Vivo Dynamic Imaging of Blood Circulation

Diankai Liu et al.

Summary: This study introduces a series of xanthene-based NIR-II dyes, named VIXs, with VIX-4 showing the best performance in terms of fluorescence emission at 1210 nm and high brightness. The dye has been successfully used for dynamically imaging the blood flow of mice, allowing for direct differentiation between arteries and veins and measurement of blood flow volume through videos. The study not only provides an effective tool for high spatial and temporal resolution bioimaging, but also presents a new promising conjugated skeleton for NIR-II dyes.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Multidisciplinary

Magnesium-Based Micromotors as Hydrogen Generators for Precise Rheumatoid Arthritis Therapy

Cong Xu et al.

Summary: Hydrogen therapy is a promising strategy for inflammation-related diseases, but its efficacy is limited due to nonpolarity and low solubility. A biocompatible magnesium micromotor coated with hyaluronic acid was developed as a hydrogen generator, showing great potential for rheumatoid arthritis therapy by producing hydrogen bubbles for motion and scavenging reactive oxygen species and inflammation. Through ultrasound-guided intra-articular injection, the micromotors effectively relieved oxidative stress, reduced inflammation cytokines, and ameliorated joint damage, showing prominent therapeutic efficacy.

NANO LETTERS (2021)

Review Engineering, Biomedical

Nanomedicine Strategies for Anti-Inflammatory Treatment of Noninfectious Arthritis

Long Chen et al.

Summary: Noninfectious arthritis encompasses chronic and progressive inflammatory disorders that require early management. Common forms include osteoarthritis, rheumatoid arthritis, and nanomedicine shows promise in improving therapeutic efficacy while reducing side effects and extending drug half-life.

ADVANCED HEALTHCARE MATERIALS (2021)

Article Chemistry, Analytical

A Fast-Responsive OFF-ON Near-Infrared-II Fluorescent Probe for In Vivo Detection of Hypochlorous Acid in Rheumatoid Arthritis

Peng Wu et al.

Summary: The study introduced an OFF-ON NIR-II fluorescent probe named PTA for imaging HClO in deep-seated early RA, showing good water solubility, high photostability, and rapid response capability. The probe was able to sensitively and specifically detect HClO both in exogenous and endogenous sources, with promising potential for diagnosis of HOCl-mediated inflammatory disorders.

ANALYTICAL CHEMISTRY (2021)

Article Multidisciplinary Sciences

Metabolically engineered stem cell-derived exosomes to regulate macrophage heterogeneity in rheumatoid arthritis

Dong Gil You et al.

Summary: Metabolically engineered exosomes have been shown to effectively reprogram macrophages' immune phenotype, demonstrating potential therapeutic efficacy in treating rheumatoid arthritis.

SCIENCE ADVANCES (2021)

Article Chemistry, Multidisciplinary

Fluorous Soluble Cyanine Dyes for Visualizing Perfluorocarbons in Living Systems

Irene Lim et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Chemistry, Analytical

Nanomolar Protein-Protein Interaction Monitoring with a Label-Free Protein-Probe Technique

Salla Valtonen et al.

ANALYTICAL CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

In vivomRNA imaging based on tripartite DNA probe mediated catalyzed hairpin assembly

Han Wu et al.

CHEMICAL COMMUNICATIONS (2020)

Article Chemistry, Multidisciplinary

Time-resolved luminescence detection of peroxynitrite using a reactivity-based lanthanide probe

Colum Breen et al.

CHEMICAL SCIENCE (2020)

Article Chemistry, Multidisciplinary

Tuned Cationic Dendronized Polymer: Molecular Scavenger for Rheumatoid Arthritis Treatment

Bo Peng et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Protein-Specific, Multicolor and 3D STED Imaging in Cells with DNA-Labeled Antibodies

Christoph Spahn et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Azulene-Derived Fluorescent Probe for Bioimaging: Detection of Reactive Oxygen and Nitrogen Species by Two-Photon Microscopy

Lloyd C. Murfin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Chemistry, Multidisciplinary

Route to Rheumatoid Arthritis by Macrophage-Derived Microvesicle-Coated Nanoparticles

Ruixiang Li et al.

NANO LETTERS (2019)

Article Biophysics

Peptide-based electrochemical biosensor for juvenile idiopathic arthritis detection

V. R. Rodovalho et al.

BIOSENSORS & BIOELECTRONICS (2018)

Article Chemistry, Multidisciplinary

Ultrabright and Fluorogenic Probes for Multicolor Imaging and Tracking of Lipid Droplets in Cells and Tissues

Mayeul Collot et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Chemistry, Multidisciplinary

Deformylation reaction-based probe for in vivo imaging of HOCl

Peng Wei et al.

CHEMICAL SCIENCE (2018)

Article Chemistry, Multidisciplinary

Perfluorocarbon-Based 19F MRI Nanoprobes for In Vivo Multicolor Imaging

Kazuki Akazawa et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

Intracellular Protein-Labeling Probes for Multicolor Single-Molecule Imaging of Immune Receptor-Adaptor Molecular Dynamics

Ryota Sato et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Article Multidisciplinary Sciences

DJ-1 controls bone homeostasis through the regulation of osteoclast differentiation

Hyuk Soon Kim et al.

NATURE COMMUNICATIONS (2017)

Article Chemistry, Multidisciplinary

Flexible Blade-Coated Multicolor Polymer Light-Emitting Diodes for Optoelectronic Sensors

Donggeon Han et al.

ADVANCED MATERIALS (2017)

Article Biophysics

In vitro and in vivo imaging of peroxynitrite by a ratiometric boronatebased fluorescent probe

Sathyadevi Palanisamy et al.

BIOSENSORS & BIOELECTRONICS (2017)

Article Chemistry, Multidisciplinary

Fluorogenic Probes for Multicolor Imaging in Living Cells

Grazvydas Lukinavicius et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Article Engineering, Biomedical

A Truncated IL-17RC Peptide Ameliorates Synovitis and Bone Destruction of Arthritic Mice

Yuxuan Du et al.

Advanced Healthcare Materials (2016)

Article Chemistry, Multidisciplinary

Development of a Sensitive Bioluminogenic Probe for Imaging Highly Reactive Oxygen Species in Living Rats

Ryosuke Kojima et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Chemistry, Multidisciplinary

Single Fluorescent Probe Responds to H2O2, NO, and H2O2/NO with Three Different Sets of Fluorescence Signals

Lin Yuan et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

Article Chemistry, Multidisciplinary

A Near-IR Reversible Fluorescent Probe Modulated by Selenium for Monitoring Peroxynitrite and Imaging in Living Cells

Fabiao Yu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Article Chemistry, Multidisciplinary

A highly selective fluorescent probe for the detection and imaging of peroxynitrite in living cells

Dan Yang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)