4.5 Review

Cardiovascular disease risk and pathogenesis in systemic lupus erythematosus

Related references

Note: Only part of the references are listed.
Article Rheumatology

All-cause and cause-specific mortality in systemic lupus erythematosus: a population-based study

Bahar Moghaddam et al.

Summary: This study demonstrates a persistent mortality gap in all-cause and cause-specific deaths in SLE patients compared with the general population.

RHEUMATOLOGY (2022)

Article Rheumatology

Proteomic, biomechanical and functional analyses define neutrophil heterogeneity in systemic lupus erythematosus

Kathleen R. Bashant et al.

Summary: The study identified proteomic differences and rougher cell surfaces in SLE LDGs compared to SLE NDNs, suggesting potential increased retention in microvasculature networks.

ANNALS OF THE RHEUMATIC DISEASES (2021)

Article Dermatology

Use of hydroxychloroquine and risk of major adverse cardiovascular events in patients with lupus erythematosus: A Danish nationwide cohort study

Jeanette Halskou Haugaard et al.

Summary: The use of hydroxychloroquine may reduce the risk of cardiovascular events in patients with LE, especially in those with SLE and CLE.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)

Review Medicine, Research & Experimental

Bite of the wolf: innate immune responses propagate autoimmunity in lupus

Sarthak Gupta et al.

Summary: The etiopathogenesis of systemic lupus erythematosus involves a complex interplay between genetic susceptibility factors and the environment, leading to abnormal cell death and immune dysregulation. Recent research has highlighted the important roles of components of the innate immune system, such as neutrophils and interferons, in the pathogenesis of lupus and their potential for novel therapeutic strategies.

JOURNAL OF CLINICAL INVESTIGATION (2021)

Review Pediatrics

The potential role of Colchicine in preventing coronary vascular disease in childhood-onset lupus: a new view on an old drug

Dori Abel et al.

Summary: There is a need for studies to investigate the potential role of colchicine for cardiovascular protection in pediatric patients with systemic lupus erythematous.

PEDIATRIC RHEUMATOLOGY (2021)

Review Hematology

PAD4 takes charge during neutrophil activation: Impact of PAD4 mediated NET formation on immune-mediated disease

Xiaosong Liu et al.

Summary: This review provides insights into the structure-activity relationships of PAD4 and its involvement in autoimmune disorders and thrombo-inflammatory diseases, highlighting the crucial role of PAD4-mediated NET formation in the pathogenesis of various diseases. Advances in understanding PAD4 function are essential for the development of specific inhibitors to combat and prevent autoimmune disorders and inflammatory diseases.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2021)

Article Multidisciplinary Sciences

Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus

Sarfaraz A. Hasni et al.

Summary: Increased risk of premature cardiovascular disease in systemic lupus erythematosus (SLE) is mitigated by the Janus kinase inhibitor tofacitinib, demonstrated in a Phase 1 double-blind randomized trial in SLE patients where tofacitinib showed safety and improvements in cardiometabolic and immunologic parameters.

NATURE COMMUNICATIONS (2021)

Article Rheumatology

A Panel of Biomarkers Associates With Increased Risk for Cardiovascular Events in Women With Systemic Lupus Erythematosus

Brian J. Skaggs et al.

Summary: The study found that a high PREDICTS score and hypertension increase the risk of new MACEs in patients with SLE.

ACR OPEN RHEUMATOLOGY (2021)

Article Rheumatology

Hydroxychloroquine is associated with lower platelet activity and improved vascular health in systemic lupus erythematosus

MacIntosh Grant Cornwell et al.

Summary: The study showed that the use of hydroxychloroquine (HCQ) in SLE patients is associated with decreased platelet activation and expression of related transcripts, as well as improved vascular health.

LUPUS SCIENCE & MEDICINE (2021)

Article Rheumatology

Patients with SLE have higher risk of cardiovascular events and mortality in comparison with controls with the same levels of traditional risk factors and intima-media measures, which is related to accumulated disease damage and antiphospholipid syndrome: a case-control study over 10 years

Sofia Ajeganova et al.

Summary: In patients with mild SLE of more than 10 years duration, there is a threefold to fourfold increased risk of CV events and death compared with persons who do not have SLE with similar pattern of traditional CV risk factors, cIMT and presence of carotid plaque. SLICC, SLE-APS and subclinical atherosclerosis may indicate a group at risk of worse outcome in SLE.

LUPUS SCIENCE & MEDICINE (2021)

Review Pediatrics

Immunological pathogenesis and treatment of systemic lupus erythematosus

Lu Pan et al.

WORLD JOURNAL OF PEDIATRICS (2020)

Review Immunology

The Emerging Role of B Lymphocytes in Cardiovascular Disease

Luigi Adamo et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 38 (2020)

Review Cardiac & Cardiovascular Systems

T cell subsets and functions in atherosclerosis

Ryosuke Saigusa et al.

NATURE REVIEWS CARDIOLOGY (2020)

Article Medicine, General & Internal

Colchicine in Patients with Chronic Coronary Disease

Stefan M. Nidorf et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Review Immunology

T Cells in Autoimmunity-Associated Cardiovascular Diseases

Daniella Muallem Schwartz et al.

FRONTIERS IN IMMUNOLOGY (2020)

Review Cardiac & Cardiovascular Systems

Imaging Risk in Multisystem Inflammatory Diseases

Ignatios Ikonomidis et al.

JACC-CARDIOVASCULAR IMAGING (2019)

Review Rheumatology

2019 update of the EULAR recommendations for the management of systemic lupus erythematosus

Antonis Fanouriakis et al.

ANNALS OF THE RHEUMATIC DISEASES (2019)

Article Medicine, General & Internal

Long-Term Hydroxychloroquine Therapy and Risk of Coronary Artery Disease in Patients with Systemic Lupus Erythematosus

Deng-Ho Yang et al.

JOURNAL OF CLINICAL MEDICINE (2019)

Article Biochemistry & Molecular Biology

Single-cell immune landscape of human atherosclerotic plaques

Dawn M. Fernandez et al.

NATURE MEDICINE (2019)

Article Medicine, General & Internal

Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction

Jean-Claude Tardif et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Multidisciplinary Sciences

Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus

Pragnesh Mistry et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Cardiac & Cardiovascular Systems

Immunity and Inflammation in Atherosclerosis

Dennis Wolf et al.

CIRCULATION RESEARCH (2019)

Article Rheumatology

Platelet-bound C4d, low C3 and lupus anticoagulant associate with thrombosis in SLE

Michelle A. Petri et al.

LUPUS SCIENCE & MEDICINE (2019)

Article Rheumatology

Development of a systemic lupus erythematosus cardiovascular risk equation

Michelle A. Petri et al.

LUPUS SCIENCE & MEDICINE (2019)

Article Cardiac & Cardiovascular Systems

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry

Holger Winkels et al.

CIRCULATION RESEARCH (2018)

Article Medicine, General & Internal

Cardiorespiratory fitness and age-related arterial stiffness in women with systemic lupus erythematosus

Cristina Montalban-Mendez et al.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2018)

Article Immunology

Myeloid-Specific Deletion of Peptidylarginine Deiminase 4 Mitigates Atherosclerosis

Yudong Liu et al.

FRONTIERS IN IMMUNOLOGY (2018)

Review Pharmacology & Pharmacy

Hydroxychloroquine in systemic lupus erythematosus (SLE)

C. Ponticelli et al.

EXPERT OPINION ON DRUG SAFETY (2017)

Article Rheumatology

Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction

Yasuko Furumoto et al.

ARTHRITIS & RHEUMATOLOGY (2017)

Article Rheumatology

Update on colchicine, 2017

Anastasia Slobodnick et al.

RHEUMATOLOGY (2017)

Review Cardiac & Cardiovascular Systems

MR/PET Imaging of the Cardiovascular System

Philip M. Robson et al.

JACC-CARDIOVASCULAR IMAGING (2017)

Article Hematology

Neutrophil Extracellular Traps Drive Endothelial-to-Mesenchymal Transition

Elmar Pieterse et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)

Article Hematology

Activated Platelets Induce Endothelial Cell Activation via an Interleukin-1 Pathway in Systemic Lupus Erythematosus

Sokha Nhek et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)

Article Immunology

Type I interferon responses drive intrahepatic T cells to promote metabolic syndrome

Magar Ghazarian et al.

SCIENCE IMMUNOLOGY (2017)

Article Hematology

Effects of Long-Term Type I Interferon on the Arterial Wall and Smooth Muscle Progenitor Cells Differentiation

Yanpeng Diao et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2016)

Article Rheumatology

Heart involvement in systemic lupus erythematosus: a systemic review and meta-analysis

Junzhe Chen et al.

CLINICAL RHEUMATOLOGY (2016)

Review Immunology

T cells in Systemic Lupus Erythematosus

Abel Suarez-Fueyo et al.

CURRENT OPINION IN IMMUNOLOGY (2016)

Article Medicine, Research & Experimental

Hydroxychloroquine, a promising choice for coronary artery disease?

Lizhe Sun et al.

MEDICAL HYPOTHESES (2016)

Review Rheumatology

New insights into the immunopathogenesis of systemic lupus erythematosus

George C. Tsokos et al.

NATURE REVIEWS RHEUMATOLOGY (2016)

Review Rheumatology

Dyslipidemia in systemic lupus erythematosus: just another comorbidity?

Konstantinos Tselios et al.

SEMINARS IN ARTHRITIS AND RHEUMATISM (2016)

Review Rheumatology

Mortality in Systemic Lupus Erythematosus: an Updated Review

Cesar E. Fors Nieves et al.

CURRENT RHEUMATOLOGY REPORTS (2016)

Article Multidisciplinary Sciences

Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

Annika Warnatsch et al.

SCIENCE (2015)

Article Cell Biology

Normalization of CD4+ T cell metabolism reverses lupus

Yiming Yin et al.

SCIENCE TRANSLATIONAL MEDICINE (2015)

Article Rheumatology

Impaired serum cholesterol efflux capacity in rheumatoid arthritis and systemic lupus erythematosus

Nicoletta Ronda et al.

ANNALS OF THE RHEUMATIC DISEASES (2014)

Article Peripheral Vascular Disease

Inflammation and Cardiovascular Disease: From Pathogenesis to Therapeutic Target

Enrica Golia et al.

CURRENT ATHEROSCLEROSIS REPORTS (2014)

Article Medicine, Research & Experimental

Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus

Jason S. Knight et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Immunology

Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process

Consol Farrera et al.

JOURNAL OF IMMUNOLOGY (2013)

Article Medicine, Research & Experimental

Auto-antibodies to vascular endothelial cadherin in humans: association with autoimmune diseases

L. Bouillet et al.

LABORATORY INVESTIGATION (2013)

Article Cardiac & Cardiovascular Systems

Measurement of Arterial Activity on Routine FDG PET/CT Images Improves Prediction of Risk of Future CV Events

Amparo L. Figueroa et al.

JACC-CARDIOVASCULAR IMAGING (2013)

Article Hematology

BAFF Receptor Deficiency Reduces the Development of Atherosclerosis in Mice-Brief Report

Andrew P. Sage et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)

Article Rheumatology

Use of atorvastatin in systemic lupus erythematosus in children and adolescents

L. E. Schanberg et al.

ARTHRITIS AND RHEUMATISM (2012)

Review Immunology

Activation of PAD4 in NET formation

Amanda S. Rohrbach et al.

FRONTIERS IN IMMUNOLOGY (2012)

Article Peripheral Vascular Disease

Arterial Stiffening, Wave Reflection, and Inflammation in Habitually Exercising Systemic Lupus Erythematosus Patients

Jill N. Barnes et al.

AMERICAN JOURNAL OF HYPERTENSION (2011)

Article Rheumatology

Lupus Atherosclerosis Prevention Study (LAPS)

M. A. Petri et al.

ANNALS OF THE RHEUMATIC DISEASES (2011)

Review Biochemistry & Molecular Biology

Macrophages in the Pathogenesis of Atherosclerosis

Kathryn J. Moore et al.

Review Rheumatology

Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review

G. Ruiz-Irastorza et al.

ANNALS OF THE RHEUMATIC DISEASES (2010)

Article Cardiac & Cardiovascular Systems

Arterial Stiffness and Cardiovascular Events The Framingham Heart Study

Gary F. Mitchell et al.

CIRCULATION (2010)

Article Biochemistry & Molecular Biology

The Th17/Treg functional imbalance during atherogenesis in ApoE-/- mice

Jiang-jiao Xie et al.

CYTOKINE (2010)

Article Cardiac & Cardiovascular Systems

Prediction of Cardiovascular Events and All-Cause Mortality With Arterial Stiffness A Systematic Review and Meta-Analysis

Charalambos Vlachopoulos et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)

Review Cell Biology

Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

E. Maury et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)

Article Rheumatology

Th17 and Natural Treg Cell Population Dynamics in Systemic Lupus Erythematosus

Ji Yang et al.

ARTHRITIS AND RHEUMATISM (2009)

Article Medicine, General & Internal

Subclinical atherosclerosis in rheumatoid arthritis and systemic lupus erythematosus

Jane E. Salmon et al.

AMERICAN JOURNAL OF MEDICINE (2008)

Article Rheumatology

Accumulation of coronary artery disease risk factors actors over three years:: Data from an international inception cohort

M. B. Urowitz et al.

ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH (2008)

Article Allergy

Adiponectin and inflammation: Consensus and controversy

Giamila Fantuzzi

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2008)

Review Cardiac & Cardiovascular Systems

Cardiac involvement in systemic inflammatory diseases

Daniel C. Knockaert

EUROPEAN HEART JOURNAL (2007)

Article Multidisciplinary Sciences

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

Daniel Mucida et al.

SCIENCE (2007)

Review Cardiac & Cardiovascular Systems

Expert consensus document on arterial stiffness: methodological issues and clinical applications

Stephane Laurent et al.

EUROPEAN HEART JOURNAL (2006)

Article Medicine, General & Internal

Preclinical carotid atherosclerosis in patients with rheumatoid arthritis

MJ Roman et al.

ANNALS OF INTERNAL MEDICINE (2006)

Article Rheumatology

Platelet C4d is highly specific for systemic lupus erythematosus

JS Navratil et al.

ARTHRITIS AND RHEUMATISM (2006)

Review Cardiac & Cardiovascular Systems

Adipose tissue, inflammation, and cardiovascular disease

AH Berg et al.

CIRCULATION RESEARCH (2005)

Review Urology & Nephrology

Endothelial dysfunction

DH Endemann et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2004)

Article Medicine, General & Internal

Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosus

MJ Roman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)

Article Medicine, General & Internal

The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men

HM Lakka et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)